Hypothesis

86 Matching Annotations

Aug 2025
52.53.155.43 52.53.155.43

2025.08.13.669552v1.full-html.html

1
1. scibot 22 Aug 2025
  
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  RRID:AB_493731
  
  DOI: 10.1101/2025.08.13.669552
  
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52.53.155.43/cbef6d49734833e21d46745b8a2764b4c745ed76/2025.08.13.669552v1.full-html.html
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

1
1. scibot 01 Jul 2025
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Gut microbiota dysbiosis induced by brain tumors modulates the efficacy of immunotherapy

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115825
  
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sciencedirect.com/science/article/pii/S2211124725005960
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

1
1. scibot 03 Jun 2025
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

1
1. scibot 29 May 2025
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
Apr 2025
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Protocol for investigating the impact of transcription regulator deficiency on tumor-specific CD8+ T cell responses via adoptive cell transfer

1
1. scibot 03 Apr 2025
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.xpro.2025.103703
  
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sciencedirect.com/science/article/pii/S2666166725001091
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

1
1. scibot 04 Mar 2025
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
Dec 2024
www.sciencedirect.com www.sciencedirect.com

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

1
1. scibot 02 Dec 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2024.10.010
  
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sciencedirect.com/science/article/pii/S1074761324004904
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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

1
1. scibot 02 Dec 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2024.115023
  
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sciencedirect.com/science/article/pii/S2211124724013743
Oct 2024
www.biorxiv.org www.biorxiv.org

Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy

1
1. scibot 02 Oct 2024
  
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  AB_493731
  
  DOI: 10.1101/2024.09.09.612140
  
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biorxiv.org/content/10.1101/2024.09.09.612140v1
Sep 2024
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Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

1
1. scibot 25 Sep 2024
  
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  RRID:AB_493730
  
  DOI: 10.1016/j.cell.2019.07.032
  
  Resource: (BioLegend Cat# 109821, RRID:AB_493730)
  
  Curator: @ethanbadger
  
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  RRID:AB_493730 RRID:AB_493731 RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S0092867419308311
www.sciencedirect.com www.sciencedirect.com

The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

1
1. scibot 04 Sep 2024
  
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  AB_493731
  
  DOI: 10.1016/j.celrep.2024.114690
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S2211124724010416
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment

1
1. scibot 04 Sep 2024
  
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  AB_493731
  
  DOI: 10.1016/j.isci.2024.110810
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11404196/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

1
1. scibot 20 Aug 2024
  
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  AB_493731
  
  DOI: 10.1016/j.cell.2024.07.018
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S0092867424007785
www.science.org www.science.org

Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics

1
1. scibot 02 Aug 2024
  
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  RRID:AB_493731
  
  DOI: 10.1126/sciadv.adk2298
  
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science.org/doi/10.1126/sciadv.adk2298
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

2
1. scibot 25 Jul 2024
  
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  AB_493731
  
  DOI: 10.1016/j.celrep.2024.114542
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
  Curator: @scibot
  
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  RRID:AB_493731
2. scibot 25 Jul 2024
  
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  AB_493731
  
  DOI: 10.1016/j.celrep.2024.114542
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_493731
  
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sciencedirect.com/science/article/pii/S2211124724008714
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol to study the immune profile of syngeneic mouse tumor models

1
1. scibot 14 Jul 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.xpro.2024.103139
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11234017/
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers

1
1. scibot 05 Jun 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2024.05.009
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S1074761324002632
Apr 2024
www.sciencedirect.com www.sciencedirect.com

LKB1 prevents ILC2 exhaustion to enhance antitumor immunity

1
1. scibot 26 Apr 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.113579
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S2211124723015917
www.sciencedirect.com www.sciencedirect.com

Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

1
1. scibot 05 Apr 2024
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.ccell.2024.03.005
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S1535610824000904
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics

1
1. scibot 09 Mar 2024
  
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  RRID:AB_493731
  
  DOI: 10.1126/sciadv.adk2298
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10917351/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas

1
1. scibot 06 Feb 2024
  
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  RRID:AB_493731
  
  DOI: 10.1158/2159-8290.CD-22-1401
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

1
1. scibot 29 Dec 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2023.11.018
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S1074761323005009
www.sciencedirect.com www.sciencedirect.com

Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

1
1. scibot 17 Dec 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2023.11.005
  
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sciencedirect.com/science/article/pii/S1074761323004879
www.sciencedirect.com www.sciencedirect.com

Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation

1
1. scibot 13 Oct 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.113220
  
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sciencedirect.com/science/article/pii/S2211124723012329
Sep 2023
www.sciencedirect.com www.sciencedirect.com

CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

1
1. scibot 19 Sep 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.113084
  
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sciencedirect.com/science/article/pii/S2211124723010951
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy

1
1. scibot 25 Aug 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.ccell.2023.08.001
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/abs/pii/S1535610823002738
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues

2
1. scibot 12 Aug 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.112924
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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  RRID:AB_493731
2. scibot 04 Aug 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.celrep.2023.112924
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10504686/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells

1
1. scibot 23 Jun 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2023.05.008
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S107476132300225X
May 2023
www.sciencedirect.com www.sciencedirect.com

M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch

1
1. scibot 03 May 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2023.04.002
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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sciencedirect.com/science/article/pii/S107476132300170X
Mar 2023
europepmc.org europepmc.org

Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

1
1. scibot 28 Mar 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.stem.2023.02.010
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
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europepmc.org/article/med/36948186
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Dopamine inhibits group 2 innate lymphoid cell-driven allergic lung inflammation by dampening mitochondrial activity

1
1. scibot 18 Feb 2023
  
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  RRID:AB_49373
  
  DOI: 10.1016/j.immuni.2022.12.017
  
  Resource: (BioLegend Cat# 109822, RRID:AB_493731)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_493731
  
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  RRID:AB_493731 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1074761322006756
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing

1
1. scibot 12 Jan 2023
  
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  RRID:AB_493731
  
  DOI: 10.1016/j.immuni.2022.12.004
  
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A culture platform to study quiescent hematopoietic stem cells following genome editing

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Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells

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Identification and characterization of innate lymphoid cells generated from pluripotent stem cells

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Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

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Epigenetic modifier SMCHD1 maintains a normal pool of long-term hematopoietic stem cells.

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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

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IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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Untitled document

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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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Untitled document

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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

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Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth

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DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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Functional characterization of the dural sinuses as a neuroimmune interface

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A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

1
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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

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Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells

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C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

1
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Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction

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Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice

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Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles

1
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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

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Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

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Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting

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  RRID:AB_493731
  
  DOI: 10.1016/j.cell.2019.11.032
  
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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.08.003
  
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Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.ccell.2019.10.008
  
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IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.077
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.105
  
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.04.001
  
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Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

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Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation

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1. scibot 05 Nov 2018
  
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Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism

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1. scibot 05 Nov 2018
  
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Segmented Filamentous Bacteria Provoke Lung Autoimmunity by Inducing Gut-Lung Axis Th17 Cells Expressing Dual TCRs

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Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction

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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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1. scibot 08 Nov 2017
  
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Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase

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1. scibot 08 Nov 2017
  
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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

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1. scibot 08 Nov 2017
  
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Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

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1. scibot 08 Nov 2017
  
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