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Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Spatial and single-cell transcriptomics reveal the reorganization of cerebellar microglia with aging

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116624
  
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sciencedirect.com:5037/science/article/pii/S2211124725013968
Sep 2025
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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116350
  
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sciencedirect.com/science/article/pii/S2211124725011210
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.neuron.2024.07.015
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11446403/
Aug 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Colony Stimulating Factor-1 (CSF-1) and Interleukin-34 (IL-34) Differentially Alter White Matter and Gray Matter Microglia and Oligodendrocyte Progenitor Cells

1
1. scibot 15 Aug 2025
  
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  DOI: 10.1111/jnc.70186
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70186
www.biorxiv.org www.biorxiv.org

Spared cognitive and social function following perinatal ablation of ATRX despite transient microglia dysregulation

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1. scibot 13 Aug 2025
  
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  DOI: 10.1101/2025.08.06.668920
  
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biorxiv.org/content/10.1101/2025.08.06.668920v1
May 2025
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Ultrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102155
  
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sciencedirect.com/science/article/pii/S2666379125002289
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

1
1. scibot 27 Mar 2025
  
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  DOI: 10.1038/s41467-025-57684-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
Nov 2024
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Inhibiting AMPA receptor signaling in oligodendrocytes rescues synapse loss in a model of autoimmune demyelination

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1. scibot 26 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111226
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11577175/
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Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency

1
1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114985
  
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sciencedirect.com/science/article/pii/S2211124724013366
jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate

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1. scibot 08 Nov 2024
  
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  DOI: 10.1186/s12974-024-03272-8
  
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jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-024-03272-8
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Macrophage-mediated myelin recycling fuels brain cancer malignancy

1
1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.07.030
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11429458/
Aug 2024
link.springer.com link.springer.com

Sigma-1 receptor targeting inhibits connexin 43 based intercellular communication in chronic neuropathic pain

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1007/s00011-024-01926-0
  
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link.springer.com/article/10.1007/s00011-024-01926-0
Jul 2024
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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

1
1. scibot 27 Jul 2024
  
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  AB_2224398
  
  DOI: 10.1016/j.neuron.2024.06.029
  
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sciencedirect.com/science/article/pii/S0896627324004914
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Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression

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1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114488
  
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sciencedirect.com/science/article/pii/S2211124724008179
Jun 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity

1
1. scibot 14 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11167441/
May 2024
52.53.155.43 52.53.155.43

Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke

2
1. scibot 09 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101522
  
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2. scibot 07 May 2024
  
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  RRID:AB_521594
  
  DOI: 10.1016/j.xcrm.2024.101522
  
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52.53.155.43/23904a6df569543355b93537b87aff6dc46e4387/mmc2-html.html
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice

1
1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114144
  
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sciencedirect.com/science/article/pii/S2211124724004728
Feb 2024
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The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes

1
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113813
  
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sciencedirect.com/science/article/pii/S2211124724001414
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice

1
1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108872
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10839647/
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PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome

1
1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.cell.2024.01.009
  
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sciencedirect.com/science/article/pii/S0092867424000114
Jan 2024
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Tissue-resident macrophages specifically express Lactotransferrin and Vegfc during ear pinna regeneration in spiny mice

1
1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.12.017
  
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sciencedirect.com/science/article/pii/S1534580723006974
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing

1
1. scibot 10 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108688
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770728/
Dec 2023
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APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

2
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.029
  
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2. scibot 17 Dec 2023
  
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  RRID:AB_521594
  
  DOI: 10.1016/j.cell.2023.11.029
  
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sciencedirect.com/science/article/pii/S0092867423013156
Nov 2023
link.springer.com link.springer.com

Upregulation of Spinal MDGA1 in Rats After Nerve Injury Alters Interactions Between Neuroligin-2 and Postsynaptic Scaffolding Proteins and Increases GluR1 Subunit Surface Delivery in the Spinal Cord Dorsal Horn

1
1. scibot 17 Nov 2023
  
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  DOI: 10.1007/s11064-023-04049-w
  
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link.springer.com/article/10.1007/s11064-023-04049-w
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Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

1
1. scibot 04 Nov 2023
  
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  RRID:AB_521594
  
  DOI: 10.1007/s12035-023-03717-w
  
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link.springer.com/article/10.1007/s12035-023-03717-w
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling

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1. scibot 12 Oct 2023
  
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  RRID:AB_521594
  
  DOI: 10.1101/2023.07.13.548459
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
Sep 2023
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Tracking cell-type-specific temporal dynamics in human and mouse brains

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.cell.2023.08.042
  
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sciencedirect.com/science/article/pii/S0092867423009765
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Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease

1
1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.immuni.2023.08.008
  
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sciencedirect.com/science/article/pii/S1074761323003643
Jul 2023
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AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice

1
1. scibot 15 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107247
  
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sciencedirect.com/science/article/pii/S258900422301324X
May 2023
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Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice

1
1. scibot 14 May 2023
  
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  DOI: 10.1016/j.isci.2023.106698
  
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sciencedirect.com/science/article/pii/S2589004223007757
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VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection

1
1. scibot 12 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112489
  
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sciencedirect.com/science/article/pii/S2211124723005004
onlinelibrary.wiley.com onlinelibrary.wiley.com

Social isolation produces a sex and brain-region specific alteration of microglia state

1
1. scibot 05 May 2023
  
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  RRID:AB_521594
  
  DOI: 10.1111/ejn.15966
  
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onlinelibrary.wiley.com/doi/10.1111/ejn.15966
Apr 2023
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Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation

1
1. scibot 22 Apr 2023
  
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  AB_521594
  
  DOI: 10.1016/j.isci.2023.106613
  
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sciencedirect.com/science/article/pii/S2589004223006909
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Modulation of microglial metabolism facilitates regeneration in demyelination

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N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1

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Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1

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Massive Loss of Proprioceptive Ia Synapses in Rat Spinal Motoneurons after Nerve Crush Injuries in the Postnatal Period

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Microglia and astrocytes mediate synapse engulfment in a... : Neural Regeneration Research

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Culture Protocol and Transcriptomic Analysis of Murine SVZ NPCs and OPCs

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Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity

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Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models

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A reference human induced pluripotent stem cell line for large-scale collaborative studies

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Table 1 Antibodies and dyes compatible with mLSR-3D

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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

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Neutrophil-derived interleukin-17A participates in... : Neural Regeneration Research

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Microglial control of neuronal development via somatic purinergic junctions

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TMEM16F may be a new therapeutic target for Alzheimer’s... : Neural Regeneration Research

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Prenatal environmental stressors impair postnatal microglia function and adult behavior in males

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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

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Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain

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The E3 ubiquitin ligase RNF216/TRIAD3 is a key coordinator of the hypothalamic-pituitary-gonadal axis

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Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

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Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system

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Enhanced oxidative stress and the treatment by edaravone in mice model of amyotrophic lateral sclerosis

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Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease

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Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis

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The Multimodal MOPr/DOPr Agonist LP2 Reduces Allodynia in Chronic Constriction Injured Rats by Rescue of TGF-β1 Signalling

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Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

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PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination

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Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor to suppress microgliosis and macrophage accumulation

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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

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BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

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MicroRNA 223 Targeting ATG16L1 Affects Microglial Autophagy in the Kainic Acid Model of Temporal Lobe Epilepsy

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Untitled document

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Untitled document

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Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

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Targeting microglia using Cx3cr1-cre lines: revisiting the specificity

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Loss of APP in mice increases thigmotaxis and is associated with elevated brain expression of IL-13 and IP-10/CXCL10

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sciencedirect.com/science/article/pii/S0031938421002237
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Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

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Spinal A3 adenosine receptor activation acutely restores morphine antinociception in opioid tolerant male rats

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  DOI: 10.1002/jnr.24869
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24869
May 2021
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Hyaluronidase inhibition accelerates functional recovery from stroke in the mouse brain

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  DOI: 10.1111/jnc.15279
  
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Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M

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Apr 2021
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Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation

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Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease

1
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Jan 2021
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Microglial mTOR is neuronal protective and anti-epileptogenic in the pilocarpine model of temporal lobe epilepsy

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  DOI: 10.1523/JNEUROSCI.2754-19.2020
  
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Dec 2020
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Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy

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1. scibot 22 Dec 2020
  
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  DOI: 10.1016/j.ebiom.2020.103156
  
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Nov 2020
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Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease

1
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ncbi.nlm.nih.gov/pmc/articles/PMC7664057/
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A new genetic strategy for targeting microglia in development and disease

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  DOI: 10.7554/eLife.54590
  
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Temporal evolution of heme oxygenase-1 expression in reactive astrocytes and microglia in response to traumatic brain injury

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The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain

1
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  DOI: 10.1002/glia.23831
  
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Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss

1
1. scibot 04 Sep 2020
  
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  DOI: 10.18632/aging.103561
  
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Jan 2020
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LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease

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  DOI: 10.1016/j.cell.2019.05.056
  
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cell.com/cell/fulltext/S0092-8674(19)30627-0
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Removal of the potassium chloride co-transporter from the somatodendritic membrane of axotomized motoneurons is independent of BDNF/TrkB signaling but is controlled by neuromuscular innervation

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eneuro.org/content/6/5/ENEURO.0172-19.2019
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Inhibition of Piezo1 attenuates demyelination in the central nervous system

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  DOI: 10.1002/glia.23722
  
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Targeting microglia using Cx3cr1-cre lines: revisiting the specificity

2
1. scibot 13 Jan 2020
  
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TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease

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Valproic acid affects neuronal fate and microglial function via enhancing autophagic flux in mice after traumatic brain injury

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onlinelibrary.wiley.com/doi/10.1111/jnc.14892
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Untitled document

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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.085
  
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Untitled document

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  DOI: 10.1523/JNEUROSCI.2152-17.2018
  
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Untitled document

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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

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Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog

1
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nature.com/articles/s41598-017-05864-2

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