48 Matching Annotations
  1. Dec 2024
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    Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells
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    sciencedirect.com/science/article/pii/S2211124724013457
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    Self-organized pattern formation in the developing mouse neural tube by a temporal relay of BMP signaling
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    sciencedirect.com/science/article/pii/S1534580724006646
  4. Oct 2024
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    The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin
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    sciencedirect.com/science/article/pii/S2211124724011653
  6. Jul 2024
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    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
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  8. May 2024
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    Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition
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    sciencedirect.com/science/article/pii/S1534580724002971
  10. Apr 2024
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    Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids
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    sciencedirect.com/science/article/pii/S1934590924000894
  12. Jan 2024
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    Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
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  14. Nov 2023
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    Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
    1
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    sciencedirect.com/science/article/pii/S2589004223024410
  16. Sep 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
    1
    1. scibot 08 Sep 2023
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      DOI: 10.7554/eLife.90006

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    ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
  18. Apr 2023
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    Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
    1
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    sciencedirect.com/science/article/pii/S089662732300034X
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    Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes
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  21. Mar 2023
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    Protocol to generate human pluripotent stem cell-derived pancreatic β cells through methionine and zinc deprivation
    1
    1. scibot 28 Mar 2023
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    sciencedirect.com/science/article/pii/S2666166723001417
  23. Aug 2022
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    Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
    1
    1. scibot 23 Aug 2022
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    sciencedirect.com/science/article/pii/S1534580722005317
  25. Jul 2022
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    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
    1
    1. scibot 27 Jul 2022
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    sciencedirect.com/science/article/pii/S2211124722009263
  27. Jun 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis
    1
    1. scibot 30 Jun 2022
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      DOI: 10.1016/j.isci.2022.104594

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    ncbi.nlm.nih.gov/pmc/articles/PMC9212970/
  29. Mar 2022
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
    1
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    sciencedirect.com/science/article/pii/S2211124722001498
  31. Nov 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103221

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    ncbi.nlm.nih.gov/pmc/articles/PMC8554488/
  33. Sep 2021
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    The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production
    1
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    sciencedirect.com/science/article/pii/S1534580721006730
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    Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
    1
    1. scibot 04 Sep 2021
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      DOI: 10.1016/j.stem.2021.08.001

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    sciencedirect.com/science/article/pii/S1934590921003386
  36. Aug 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner
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    1. scibot 25 Aug 2021
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      DOI: 10.7554/eLife.67121

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    ncbi.nlm.nih.gov/pmc/articles/PMC8378848/
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    RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish
    1
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    sciencedirect.com/science/article/pii/S1534580721006043
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
    1
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      DOI: 10.1210/js.2017-00081

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    ncbi.nlm.nih.gov/pmc/articles/PMC5542010/
  40. academic.oup.com academic.oup.com
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      DOI: 10.1210/js.2017-00081

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    academic.oup.com/jes/article/1/5/385/3084588
  41. www.frontiersin.org www.frontiersin.org
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      DOI: 10.3389/fendo.2018.00791

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    frontiersin.org/article/10.3389/fendo.2018.00791/full
  42. Jul 2021
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.cell.2017.11.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC5786493/
  44. May 2021
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    A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation
    1
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      DOI: 10.1016/j.devcel.2020.08.003

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    sciencedirect.com/science/article/pii/S1534580720306274
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    Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
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      DOI: 10.1016/j.devcel.2020.06.034

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    sciencedirect.com/science/article/pii/S1534580720305426
  47. Apr 2021
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    Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
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      DOI: 10.1016/j.stem.2021.02.003

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  49. Feb 2021
  50. elifesciences.org elifesciences.org
    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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      DOI: 10.7554/eLife.59067

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    elifesciences.org/articles/59067
  51. Dec 2020
  52. www.sciencedirect.com www.sciencedirect.com
    Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans
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    sciencedirect.com/science/article/pii/S2211124720314145
  53. Nov 2020
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
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      DOI: 10.7554/eLife.60234

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    ncbi.nlm.nih.gov/pmc/articles/PMC7655103/
  55. Sep 2020
  56. elifesciences.org elifesciences.org
    The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
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      DOI: 10.7554/eLife.57381

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    elifesciences.org/articles/57381
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    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
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    sciencedirect.com/science/article/pii/S1534580720300162
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    ARL13B regulates Sonic hedgehog signaling from outside primary cilia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7075693/
  59. Jan 2020
  60. www.sciencedirect.com www.sciencedirect.com
    Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal
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      DOI: 10.1016/j.celrep.2019.07.087

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    sciencedirect.com/science/article/pii/S2211124719310034
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    Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A
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      DOI: 10.1016/j.stem.2019.07.007

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    sciencedirect.com/science/article/pii/S1934590919303054
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    TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation
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      DOI: 10.1016/j.celrep.2019.07.035

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
    1
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      DOI: 10.7554/eLife.38519

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    ncbi.nlm.nih.gov/pmc/articles/PMC6294552/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.3389/fendo.2018.00791

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    ncbi.nlm.nih.gov/pmc/articles/PMC6334491/
  65. Nov 2018
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors’ activity in an E-box-dependent manner
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      RRID:AB_532378

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6126921/
  67. www.sciencedirect.com www.sciencedirect.com
    https://www.ncbi.nlm.nih.gov/pubmed/29290584
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    1. scibot 05 Nov 2018
      RRID:AB_532378

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1534580717309887
  68. www.sciencedirect.com www.sciencedirect.com
    Intrinsic Immunity Shapes Viral Resistance of Stem Cells
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S009286741731365X
  69. Nov 2017
  70. www.sciencedirect.com www.sciencedirect.com
    Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord
    1
    1. scibot 08 Nov 2017
      RRID_AB532378

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1044743116301579
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
    2
    1. scibot 08 Nov 2017
      RRID:AB_532378

      Curator: @patriciaelyse_

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    2. scibot 08 Nov 2017
      AB_532378

      Curator: @chewbeccax

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    ncbi.nlm.nih.gov/pmc/articles/PMC5542010/
  72. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling
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    1. scibot 08 Nov 2017
      AB_532378

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1097276517301302