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    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
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  3. May 2024
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    Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition
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  5. Apr 2024
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    Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids
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  7. Jan 2024
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    Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
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  9. Nov 2023
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    Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
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  11. Sep 2023
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    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10482429/
  13. Apr 2023
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    Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
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    Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes
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  16. Mar 2023
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    Protocol to generate human pluripotent stem cell-derived pancreatic β cells through methionine and zinc deprivation
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    sciencedirect.com/science/article/pii/S2666166723001417
  18. Aug 2022
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    Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
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  20. Jul 2022
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    Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization
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    sciencedirect.com/science/article/pii/S2211124722009263
  22. Jun 2022
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    SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis
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  24. Mar 2022
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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  26. Nov 2021
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    An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients
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  28. Sep 2021
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    The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production
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    Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
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  31. Aug 2021
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    Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC8378848/
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    RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish
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    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
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      DOI: 10.1210/js.2017-00081

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    ncbi.nlm.nih.gov/pmc/articles/PMC5542010/
  35. academic.oup.com academic.oup.com
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  37. Jul 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  39. May 2021
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    A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation
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    sciencedirect.com/science/article/pii/S1534580720306274
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    Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
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  42. Apr 2021
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    Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
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    sciencedirect.com/science/article/pii/S1934590921000539
  44. Feb 2021
  45. elifesciences.org elifesciences.org
    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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    elifesciences.org/articles/59067
  46. Dec 2020
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    Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans
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    sciencedirect.com/science/article/pii/S2211124720314145
  48. Nov 2020
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure
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    ncbi.nlm.nih.gov/pmc/articles/PMC7655103/
  50. Sep 2020
  51. elifesciences.org elifesciences.org
    The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
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    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
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    sciencedirect.com/science/article/pii/S1534580720300162
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    ARL13B regulates Sonic hedgehog signaling from outside primary cilia
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      DOI: 10.7554/eLife.50434

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    ncbi.nlm.nih.gov/pmc/articles/PMC7075693/
  54. Jan 2020
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    Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal
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    sciencedirect.com/science/article/pii/S2211124719310034
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    Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A
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    sciencedirect.com/science/article/pii/S1934590919303054
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    TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation
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    sciencedirect.com/science/article/pii/S2211124719309325
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
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      DOI: 10.7554/eLife.38519

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    ncbi.nlm.nih.gov/pmc/articles/PMC6294552/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6334491/
  60. Nov 2018
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors’ activity in an E-box-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC6126921/
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    https://www.ncbi.nlm.nih.gov/pubmed/29290584
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    sciencedirect.com/science/article/pii/S1534580717309887
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    Intrinsic Immunity Shapes Viral Resistance of Stem Cells
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    sciencedirect.com/science/article/pii/S009286741731365X
  64. Nov 2017
  65. www.sciencedirect.com www.sciencedirect.com
    Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord
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      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_532378
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    sciencedirect.com/science/article/pii/S1044743116301579
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
    2
    1. scibot 08 Nov 2017
      RRID:AB_532378

      Curator: @patriciaelyse_

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      (DSHB Cat# F55A10, RRID:AB_532378)

      SciCrunch record: RRID:AB_532378

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_532378 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_532378

      Curator: @chewbeccax

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      (DSHB Cat# F55A10, RRID:AB_532378)

      SciCrunch record: RRID:AB_532378

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      RRID:AB_532378 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5542010/
  67. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling
    1
    1. scibot 08 Nov 2017
      AB_532378

      Curator: @gabimpine

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      (DSHB Cat# F55A10, RRID:AB_532378)

      SciCrunch record: RRID:AB_532378

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_532378 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517301302