156 Matching Annotations
  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model
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    1. scibot 05 Oct 2024
      RRID:AB_561049

      DOI: 10.3389/fphar.2024.1377081

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    ncbi.nlm.nih.gov/pmc/articles/PMC11439770/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeated seizures lead to progressive ventilatory dysfunction in SSKcnj16−/− rats
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1152/japplphysiol.00072.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10642517/
  4. Sep 2024
  5. www.sciencedirect.com www.sciencedirect.com
    An ILK/STAT3 pathway controls glioblastoma stem cell plasticity
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1016/j.devcel.2024.09.003

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    sciencedirect.com/science/article/pii/S1534580724005318
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Expression of PACAP/VIP Receptors in the Post-Mortem CNS White Matter of Multiple Sclerosis Donors
    1
    1. scibot 30 Aug 2024
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      DOI: 10.3390/ijms25168850

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    ncbi.nlm.nih.gov/pmc/articles/PMC11354662/
  8. www.sciencedirect.com www.sciencedirect.com
    Acetate enables metabolic fitness and cognitive performance during sleep disruption
    1
    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S1550413124002900
  9. www.sciencedirect.com www.sciencedirect.com
    Regulation of Glycolysis-Derived L-lactate Production in Astrocytes Rescues the Memory Deficits and Aβ Burden in Early Alzheimer’s Disease Models
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.phrs.2024.107357

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    sciencedirect.com/science/article/pii/S1043661824003025
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human-induced pluripotent stem cell–derived neural stem cell exosomes improve blood–brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis
    1
    1. scibot 21 Aug 2024
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      DOI: 10.4103/NRR.NRR-D-23-01889

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    ncbi.nlm.nih.gov/pmc/articles/PMC11317932/
  11. www.sciencedirect.com www.sciencedirect.com
    Protocol to establish a demyelinated animal model to study hippocampal neurogenesis and cognitive function in adult rodents
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.xpro.2024.103242

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    sciencedirect.com/science/article/pii/S2666166724004076
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
    1
    1. scibot 02 Aug 2024
      3670AB_2130165Cell Signaling

      DOI: 10.1186/s13024-023-00611-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10161466/
  13. Jul 2024
  14. www.mdpi.com www.mdpi.com
    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
    1
    1. scibot 26 Jul 2024
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      DOI: 10.3390/ijms25137168

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    mdpi.com/1422-0067/25/13/7168
  15. www.sciencedirect.com www.sciencedirect.com
    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
    1
    1. scibot 24 Jul 2024
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    sciencedirect.com/science/article/pii/S155041312400192X
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 23 Jul 2024
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      DOI: 10.1002/1873-3468.14978

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14978
  17. www.sciencedirect.com www.sciencedirect.com
    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
    2
    1. scibot 04 Jul 2024
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      DOI: 10.1016/j.nbd.2024.106586

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      DOI: 10.1016/j.nbd.2024.106586

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    sciencedirect.com/science/article/pii/S0969996124001864
  18. Jun 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity
    1
    1. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110006

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    pmc.ncbi.nlm.nih.gov/articles/PMC11167441/
  20. May 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
    1
    1. scibot 21 May 2024
      Cell SignallingCat# 3670T

      DOI: 10.1016/j.immuni.2024.04.023

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    sciencedirect.com/science/article/pii/S1074761324002280
  22. www.sciencedirect.com www.sciencedirect.com
    Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.celrep.2024.114226

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    sciencedirect.com/science/article/pii/S2211124724005540
  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 09 May 2024
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      DOI: 10.1111/bph.16397

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16397
  24. 52.53.155.43 52.53.155.43
    Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke
    2
    1. scibot 09 May 2024
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      DOI: 10.1016/j.xcrm.2024.101522

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    2. scibot 07 May 2024
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      DOI: 10.1016/j.xcrm.2024.101522

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    52.53.155.43/23904a6df569543355b93537b87aff6dc46e4387/mmc2-html.html
  25. 52.53.155.43 52.53.155.43
    Physiological JNK3 Concentrations Are Higher in Motor-related and Disease-implicated Brain Regions of C57BL6/J Mice
    1
    1. scibot 03 May 2024
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      DOI: 10.1101/2024.01.17.575386

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    52.53.155.43/8c277b9c9751fad8ac729388c808cc5fc026fdfe/2024.01.17.575386v1.full-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats with α-synucleinopathy
    1
    1. scibot 01 May 2024
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      DOI: 10.4103/1673-5374.391190

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    ncbi.nlm.nih.gov/pmc/articles/PMC11040301/
  27. Apr 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Prophylactic zinc and therapeutic selenium administration in adult rats prevents long-term cognitive and behavioral sequelae by a transient ischemic attack.
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.heliyon.2024.e30017

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    sciencedirect.com/science/article/pii/S2405844024060481
  29. www.sciencedirect.com www.sciencedirect.com
    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114144

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    sciencedirect.com/science/article/pii/S2211124724004728
  30. Mar 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.isci.2024.109435

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960102/
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ER-stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina
    1
    1. scibot 26 Mar 2024
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      DOI: 10.1002/glia.24514

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    onlinelibrary.wiley.com/doi/10.1002/glia.24514
  33. www.sciencedirect.com www.sciencedirect.com
    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.neuron.2024.02.017

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      DOI: 10.1016/j.neuron.2024.02.017

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    sciencedirect.com/science/article/pii/S0896627324001272
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
    1
    1. scibot 12 Mar 2024
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      DOI: 10.1016/j.xcrm.2024.101413

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897598/
  35. www.mdpi.com www.mdpi.com
    Oxygen–Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes
    1
    1. scibot 09 Mar 2024
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      DOI: 10.3390/brainsci14030244

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    mdpi.com/2076-3425/14/3/244
  36. Feb 2024
  37. link.springer.com link.springer.com
    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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    1. scibot 23 Feb 2024
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      DOI: 10.1186/s12974-024-03051-5

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    link.springer.com/article/10.1186/s12974-024-03051-5
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic adhesion molecule protocadherin-γC5 mediates β-amyloid-induced neuronal hyperactivity and cognitive deficits in Alzheimer's disease
    1
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      DOI: 10.1111/jnc.16066

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16066
  39. link.springer.com link.springer.com
    Heat Shock Protein 22 Attenuates Nerve Injury-induced Neuropathic Pain Via Improving Mitochondrial Biogenesis and Reducing Oxidative Stress Mediated By Spinal AMPK/PGC-1α Pathway in Male Rats
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      DOI: 10.1007/s11481-024-10100-6

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    link.springer.com/article/10.1007/s11481-024-10100-6
  40. www.nature.com www.nature.com
    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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      DOI: 10.1038/s41698-024-00500-5

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    nature.com/articles/s41698-024-00500-5
  41. Jan 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  43. Oct 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
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      DOI: 10.1016/j.celrep.2023.113275

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    sciencedirect.com/science/article/pii/S2211124723012871
  45. www.nature.com www.nature.com
    Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment
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      DOI: 10.1038/s41467-023-42339-7

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    nature.com/articles/s41467-023-42339-7
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of G-protein-coupled receptor 39 reduces neuropathic pain in a rat model
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    1. scibot 20 Oct 2023
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      DOI: 10.4103/1673-5374.380905

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581569/
  47. Sep 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats
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      DOI: 10.1016/j.isci.2023.107792

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    sciencedirect.com/science/article/pii/S2589004223018692
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spi1 regulates the microglial/macrophage inflammatory response via the PI3K/AKT/mTOR signaling pathway after intracerebral hemorrhage
    1
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      DOI: 10.4103/1673-5374.375343

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    Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1-/- mice
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    Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction
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    LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
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    An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway
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    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
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  60. Jun 2023
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    ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer’s disease-like mouse model
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  63. May 2023
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    Ventrolateral periaqueductal gray astrocytes regulate nociceptive sensation and emotional motivation in diabetic neuropathic pain
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  68. Apr 2023
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  70. Mar 2023
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    (+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission
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    Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
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  74. Feb 2023
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    Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat
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  77. Jan 2023
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  83. Nov 2022
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  90. Sep 2022
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  96. Jul 2022
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    Somatostatin interneurons inhibit excitatory transmission mediated by astrocytic GABAB and presynaptic GABAB and adenosine A1 receptors in the hippocampus
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  99. Jun 2022
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    Basolateral amygdala astrocytes modulate of diabetic neuropathic pain and may be a potential therapeutic target for koumine
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  101. May 2022
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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    Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage
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  104. Apr 2022
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    Hedgehog signaling plays a crucial role in hyperalgesia associated with neuropathic pain in mice
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    Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT-1 expression and impairment of NKA1A2 function
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    Dihydromyricetin improves social isolation-induced cognitive impairments and astrocytic changes in mice
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  108. Mar 2022
  109. 52.53.155.43 52.53.155.43
    Vitamin C Inhibits Ubiquitination of Glutamate Transporter 1 (GLT-1) in Astrocytes by Downregulating HECTD1
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  113. Feb 2022
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  115. Jan 2022
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    Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons
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  118. Dec 2021
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    Bioactive Foods Decrease Liver and Brain Alterations Induced by a High-Fat-Sucrose Diet through Restoration of Gut Microbiota and Antioxidant Enzymes
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    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
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    Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A
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  123. Nov 2021
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    Proteomic Profiling of Astrocytic O-GlcNAc Transferase-Related Proteins in the Medial Prefrontal Cortex
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    Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study
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    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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    Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease
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  128. Sep 2021
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    Generation of a CRISPR/Cas9-corrected-hiPSC (NCCDFWi001-A-1) from a Marfan syndrome patient hiPSC with a heterozygous c.2613A > C variant in the fibrillin 1 (FBN1) gene
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    Sex-Specific Acute and Chronic Neurotoxicity of Acute Diisopropylfluorophosphate (DFP)-Intoxication in Juvenile Sprague-Dawley Rats
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    Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
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  132. Aug 2021
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sphingosine kinase 2 is essential for remyelination following cuprizone intoxication
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    Screening the expression characteristics of several miRNAs in G93A‐SOD1 transgenic mouse: altered expression of miRNA‐124 is associated with astrocyte differentiation by targeting Sox2 and Sox9
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  140. Jul 2021
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    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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    TRPV1 translocated to astrocytic membrane to promote migration and inflammatory infiltration thus promotes epilepsy after hypoxic ischemia in immature brain
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    The low levels of nerve growth factor and its upstream regulatory kinases in prion infection is reversed by resveratrol
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    Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome
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  148. May 2021
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    Role of mass effect and trehalose on early erythrolysis after experimental intracerebral haemorrhage
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    Stimulation of astrocytic sigma-1 receptor is sufficient to ameliorate inflammation- induced depression
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    The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis
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    A Role for Astroglial Calcium in Mammalian Sleep and Sleep Regulation
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  153. Feb 2021
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Spinal Cord Akt-mTOR Signaling Pathways in Postoperative Hyperalgesia Induced by Plantar Incision in Mice
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  155. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distribution and localization of phosphatidylinositol 5‐phosphate, 4‐kinase alpha and beta in the brain
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  156. Dec 2020
  157. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  158. Oct 2020
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction
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  160. Sep 2020
  161. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Noradrenaline protects neurons against H2O2‐induced death by increasing the supply of glutathione from astrocytes via β3‐adrenoceptor stimulation
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  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distribution of Aromatase in the Brain of the African Cichlid Fish Astatotilapia burtoni: Aromatase Expression, But Not Estrogen Receptors, Varies with Female Reproductive‐State
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  163. www.sciencedirect.com www.sciencedirect.com
    Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate
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    Injectable PLGA-coated ropivacaine produces a long-lasting analgesic effect on incisional pain and neuropathic pain
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    Activation of astrocytic sigma‐1 receptor exerts antidepressant‐like effect via facilitating CD38‐driven mitochondria transfer
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    A cell type‐specific expression map of NCoR1 and SMRT transcriptional co‐repressors in the mouse brain
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    Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Spinal Cord Akt-mTOR Signaling Pathways in Postoperative Hyperalgesia Induced by Plantar Incision in Mice
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  170. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria
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  171. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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  172. Jan 2020
  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury
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  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting aurora kinase B alleviates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury
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  175. www.jneurosci.org www.jneurosci.org
    Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors
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      DOI: 10.1523/JNEUROSCI.3069-18.2019

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  176. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PPARγ participates in the acquisition of brain ischemic tolerance induced by ischemic preconditioning via GLT‐1 in vivo and in vitro
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  177. www.sciencedirect.com www.sciencedirect.com
    A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism
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      DOI: 10.1016/j.chom.2019.02.013

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    Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders
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  180. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity
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  182. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture
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  183. Nov 2018
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation
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    Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA
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    Status epilepticus triggers long-lasting activation of complement C1q-C3 signaling in the hippocampus that correlates with seizure frequency in experimental epilepsy
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  191. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  192. Nov 2017
  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT‐1 by a Notch‐dependent mechanism
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    Autophagy impairment by caspase‐1‐dependent inflammation mediates memory loss in response to β‐Amyloid peptide accumulation
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  195. link.springer.com link.springer.com
    Neuroprotective effect of bee venom is mediated by reduced astrocyte activation in a subchronic MPTP-induced model of Parkinson’s disease
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