203 Matching Annotations
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    Early transcriptomic perturbations highlight the spinal cord as a key pathogenic region in spinocerebellar ataxia type 3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12846992/
  3. Jan 2026
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    Caveolin-1 Regulates Ultrastructural Alterations of Astrocytes in Chronic Cerebral Hypoperfusion
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    A positive feedback loop between FGR and p65 sustains satellite glial cell activation and chronic neuropathic pain
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    sciencedirect.com/science/article/pii/S2211124725016717
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    IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma
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    CLN3 mediates chloride efflux from lysosomes
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    Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome
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    sciencedirect.com/science/article/pii/S2211124725016298
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    Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas
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  10. Dec 2025
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    Metabolic reprogramming in the spinal cord drives the transition to pain chronicity
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    Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice
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    Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender
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  15. Nov 2025
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    PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features
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    Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
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    Repurposing Nelfinavir: AIM2 Inflammasome-Driven Anti-tumor Effects in Glioblastoma
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    Fc-Modified IVIG with Enhanced Blood–Brain Barrier Penetration Ameliorates Cognitive Deficits and Neuropathology in A53T α-Synuclein Transgenic Mice
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  20. Oct 2025
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    Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism
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  22. Sep 2025
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    Impaired macroautophagy in oligodendrocyte precursor cells suppresses neuronal plasticity via a senescence-associated signaling
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    Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate
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    Corticotropin-releasing hormone signaling from piriform cortex to amygdala mediates social homophily in opioid addiction
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    Spatially resolved transcriptomics identifies intercellular signaling post-ischemic stroke that controls neural stem cell proliferation
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  28. Aug 2025
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  30. Jul 2025
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    Astrocytes Contribute to Motor Neuron Degeneration in ALS via the TRAIL‐DR5 Signaling Pathway
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  33. Jun 2025
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    Impaired Synaptic Plasticity Mediated by Decreased GLUT1 in Hippocampal Astrocytes is Involved in Postoperative Cognitive Dysfunction in Elderly Mice
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    IL-33 secreted from astrocytes alleviates cognitive impairment associated with neuropathic pain via oxidative stress in mice
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  41. May 2025
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    Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau
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  43. Apr 2025
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  47. Mar 2025
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    Ginsenoside Rg1 alleviates chronic stress-induced depression in rats by targeting Cx43-YAP axis
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    ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity
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  50. Feb 2025
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    Distinct Roles of Astrocytes and GABAergic Neurons in the Paraventricular Thalamic Nucleus in Modulating Diabetic Neuropathic Pain
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    APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease
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  55. Jan 2025
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    Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway
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  57. Dec 2024
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    Sex-dimorphic glucose transporter-2 regulation of cAMP-protein kinase A (PKA) C-alpha pathway activity and phosphorylation in rat hypothalamic primary astrocyte cultures
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  63. Oct 2024
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    Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model
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  66. Sep 2024
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  68. Aug 2024
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  75. Jul 2024
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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  80. Jun 2024
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  82. May 2024
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    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
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    Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
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    Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke
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    Physiological JNK3 Concentrations Are Higher in Motor-related and Disease-implicated Brain Regions of C57BL6/J Mice
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  89. Apr 2024
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    Prophylactic zinc and therapeutic selenium administration in adult rats prevents long-term cognitive and behavioral sequelae by a transient ischemic attack.
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  92. Mar 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway
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    ER-stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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    TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
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    Oxygen–Glucose Deprivation Increases NR4A1 Expression and Promotes Its Extranuclear Translocation in Mouse Astrocytes
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  98. Feb 2024
  99. link.springer.com link.springer.com
    SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury
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    Synaptic adhesion molecule protocadherin-γC5 mediates β-amyloid-induced neuronal hyperactivity and cognitive deficits in Alzheimer's disease
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    Heat Shock Protein 22 Attenuates Nerve Injury-induced Neuropathic Pain Via Improving Mitochondrial Biogenesis and Reducing Oxidative Stress Mediated By Spinal AMPK/PGC-1α Pathway in Male Rats
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    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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  103. Jan 2024
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    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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  105. Oct 2023
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    Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion
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