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    N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
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    sciencedirect.com/science/article/pii/S1074761324002097
  3. Apr 2024
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    BPS Publications
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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    sciencedirect.com/science/article/pii/S2666379124001666
  8. Mar 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960275/
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    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    sciencedirect.com/science/article/pii/S0092867424002253
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    Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer’s disease
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  13. Feb 2024
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    sciencedirect.com/science/article/pii/S2211124724001232
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
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  18. Jan 2024
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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  20. Nov 2023
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    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis
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  22. Oct 2023
  23. 52.53.155.43 52.53.155.43
    CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
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  25. www.cell.com www.cell.com
    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
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    cell.com/iscience/abstract/S2589-0042(23)02074-6
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    ERK1-mediated immunomodulation of mesenchymal stem cells ameliorates inflammatory disorders
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  27. Aug 2023
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    Hedgehog receptors exert immune-surveillance roles in the epidermis across species
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    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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  31. Jul 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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    Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
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  34. Jun 2023
  35. www.microbiologyresearch.org www.microbiologyresearch.org
    IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia
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    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
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  37. May 2023
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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  41. Apr 2023
  42. www.cell.com www.cell.com
    Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation
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    cell.com/cancer-cell/abstract/S1535-6108(23)00081-8
  43. Feb 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    sciencedirect.com/science/article/pii/S2589004223002468
  45. Jan 2023
  46. academic.oup.com academic.oup.com
    ERRα attenuates vascular inflammation via enhanced NFκB degradation pathway
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      DOI: 10.1210/endocr/bqac212

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    academic.oup.com/endo/article/164/3/bqac212/6936569
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    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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    sciencedirect.com/science/article/pii/S2211124722018654
  48. www.sciencedirect.com www.sciencedirect.com
    ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
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  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor necrosis factor is a necroptosis-associated alarmin
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    ncbi.nlm.nih.gov/pmc/articles/PMC9791252/
  51. www.karger.com www.karger.com
    Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA
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  52. 52.53.155.43 52.53.155.43
    cd-22-0561-html.html
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vagus nerve stimulation is a potential treatment for ischemic stroke
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  54. Aug 2022
  55. www.sciencedirect.com www.sciencedirect.com
    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
    1
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      RRID:AB_561111

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  56. Jun 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
    1
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      DOI: 10.7554/eLife.78044

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  58. journals.lww.com journals.lww.com
    Muse cells decrease the neuroinflammatory response by... : Neural Regeneration Research
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Undercarboxylated, but not Carboxylated, Osteocalcin suppresses TNF-α induced inflammatory signaling pathway in Myoblast
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  60. May 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Ripple-selective GABAergic projection cells in the hippocampus
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  62. Apr 2022
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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  64. Mar 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone erosion in inflammatory arthritis is attenuated by Trichinella spiralis through inhibiting M1 monocyte/macrophage polarization
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  67. Feb 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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  69. Dec 2021
  70. www.sciencedirect.com www.sciencedirect.com
    CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
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    Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation
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  72. Nov 2021
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    m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity
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  74. Oct 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior
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  76. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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  77. Aug 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease
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  80. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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      RRID:AB_561111

      DOI: 10.1016/j.chom.2018.11.001

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  82. Jul 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
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      Rabbit monoclonal anti-p-IκBα

      DOI: 10.1016/j.celrep.2019.11.014

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  84. www.sciencedirect.com www.sciencedirect.com
    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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      2859

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  85. www.jneurosci.org www.jneurosci.org
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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      DOI: 10.1523/JNEUROSCI.2238-14.2014

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  87. elifesciences.org elifesciences.org
    Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2
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  88. Jun 2021
  89. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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  90. www.cell.com www.cell.com
    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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  92. www.cell.com www.cell.com
    Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior
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  93. May 2021
  94. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis
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  96. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer
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    Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors
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      pIκB (Ser23; 14D4)

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    Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells
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  99. Apr 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
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  101. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  102. Mar 2021
  103. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  104. www.sciencedirect.com www.sciencedirect.com
    IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression
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      RRID:AB_561

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  106. Feb 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits
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  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression
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      DOI: 10.1111/jnc.15184

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15184
  109. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Iron Potentiates Microglial Interleukin‐1β Secretion Induced by Amyloid‐β
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  110. Sep 2020
  111. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells
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      DOI: 10.1016/j.celrep.2020.03.038

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  112. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      DOI: 10.1016/j.cell.2020.03.040

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  113. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A marine fungus‐derived nitrobenzoyl sesquiterpenoid suppresses RANKL‐induced osteoclastogenesis and attenuates inflammatory bone destruction
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      DOI: 10.1111/bph.15179

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  114. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  115. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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  116. Jan 2020
  117. www.sciencedirect.com www.sciencedirect.com
    In Vivo Single-Cell Genotyping of Mouse Cortical Neurons Transfected with CRISPR/Cas9
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  118. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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  119. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy
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  120. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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  121. www.sciencedirect.com www.sciencedirect.com
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  122. www.sciencedirect.com www.sciencedirect.com
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  123. www.sciencedirect.com www.sciencedirect.com
    Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis
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      DOI: 10.1016/j.ebiom.2018.12.037

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  124. Nov 2018
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  126. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling
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  128. molmed.biomedcentral.com molmed.biomedcentral.com
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  129. link.springer.com link.springer.com
    IDH2 Deficiency in Microglia Decreases the Pro-inflammatory Response <Emphasis Type="Italic">via</Emphasis> the ERK and NF-κB Pathways
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  130. www.sciencedirect.com www.sciencedirect.com
    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function
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  131. www.sciencedirect.com www.sciencedirect.com
    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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  132. elifesciences.org elifesciences.org
    Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron
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  133. www.sciencedirect.com www.sciencedirect.com
    Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling
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  134. www.sciencedirect.com www.sciencedirect.com
    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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  135. www.sciencedirect.com www.sciencedirect.com
    Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
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  136. www.sciencedirect.com www.sciencedirect.com
    β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
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  137. Nov 2017
  138. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
    1
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  139. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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  140. www.sciencedirect.com www.sciencedirect.com
    The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior
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  141. www.sciencedirect.com www.sciencedirect.com
    Time-lapse imaging of p65 and IκBα translocation kinetics following Ca2 +-induced neuronal injury reveals biphasic translocation kinetics in surviving neurons
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF-κB regulates neuronal ankyrin-G via a negative feedback loop
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  143. www.sciencedirect.com www.sciencedirect.com
    Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
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