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Tobemstomig, a novel bispecific antibody, preferentially blocks PD-1 and LAG-3 on CD8 TILs to expand stem-like T-cells for sustained tumor control

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0207
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13347385/
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Engineering T Cells with a Tumor-Reactive Chimeric T Cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0777
  
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aacrjournals.org/cancerres/article/86/11/2688/785304/Engineering-T-Cells-with-a-Tumor-Reactive-Chimeric
Jun 2026
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Integrating complementary approaches reveals antigen-reactive CD4+ T cell states after SARS-CoV-2 vaccination

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1. scibot 09 Jun 2026
  
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  DOI: 10.1016/j.isci.2026.116175
  
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sciencedirect.com/science/article/pii/S2589004226015506
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Exosome-like biogenesis from the Golgi releases extracellular vesicles lacking conventional tetraspanins that mediate immune evasion in cancer

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1. scibot 06 Jun 2026
  
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  DOI: 10.64898/2026.05.13.719612
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13192941/
May 2026
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Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC

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1. scibot 14 May 2026
  
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  DOI: 10.1016/j.crmeth.2026.101339
  
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sciencedirect.com/science/article/pii/S2667237526000391
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Glucocorticoid receptor and RUNX transcription factors cooperatively drive CD8 T cell dysfunction in human cancer

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1. scibot 07 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117367
  
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sciencedirect.com/science/article/pii/S2211124726004456
Feb 2026
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Polystyrene microplastic-induced pathophysiology is driven by disruption of efferocytosis

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.009
  
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sciencedirect.com/science/article/pii/S1074761326000300
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Fungal-derived cellobiose metabolic pathway fuels T cells to bypass intratumoral glucose competition

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.cell.2026.01.015
  
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sciencedirect.com/science/article/pii/S0092867426001029
Jan 2026
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EBV infection and HLA-DR15 jointly drive multiple sclerosis by myelin peptide presentation

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1. scibot 15 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.046
  
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sciencedirect.com/science/article/pii/S0092867425014953
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Microbial-derived immunostimulatory small molecule augments anti-PD-1 therapy in lung cancer

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102519
  
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sciencedirect.com:5037/science/article/pii/S2666379125005920
Sep 2025
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Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102324
  
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sciencedirect.com/science/article/pii/S2666379125003970
Aug 2025
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Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.046
  
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sciencedirect.com/science/article/pii/S0092867425009109
link.springer.com link.springer.com

Immunotherapeutic targeting of NY-ESO-1 in malignant meningiomas with TCR-transduced T-cells

1
1. scibot 20 Aug 2025
  
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  RRID:AB_571927
  
  DOI: 10.1007/s11060-025-05200-z
  
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link.springer.com/article/10.1007/s11060-025-05200-z
Feb 2025
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Coronavirus replicase epitopes induce cross-reactive CD8 T cell responses in SARS-CoV-2-naive people with HIV-1

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111949
  
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sciencedirect.com/science/article/pii/S2589004225002093
Jun 2024
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Intergenic risk variant rs56258221 skews the fate of naive CD4+ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis

1
1. scibot 21 Jun 2024
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.xcrm.2024.101620
  
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sciencedirect.com/science/article/pii/S2666379124003240
May 2024
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Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation

1
1. scibot 21 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.023
  
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sciencedirect.com/science/article/pii/S1074761324002280
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect

1
1. scibot 15 May 2024
  
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  RRID:AB_571927
  
  DOI: 10.1084/jem.20221122
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function

1
1. scibot 12 Mar 2024
  
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  RRID:AB_571927
  
  DOI: 10.1186/s13046-024-02985-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10921725/
Dec 2023
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Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy

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1. scibot 22 Dec 2023
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.ccell.2023.11.011
  
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sciencedirect.com/science/article/pii/S1535610823004026
Nov 2023
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TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108401
  
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sciencedirect.com/science/article/pii/S2589004223024781
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Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype

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1. scibot 11 Nov 2023
  
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  RRID:AB_571927
  
  DOI: 10.26508/lsa.202302332
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10628041/
Apr 2023
aacrjournals.org aacrjournals.org

Targeting MDSC differentiation using ATRA: a phase I/II clinical trial combining pembrolizumab and all-trans retinoic acid for metastatic melanoma

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1. scibot 21 Apr 2023
  
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  DOI: 10.1158/1078-0432.CCR-22-2495
  
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aacrjournals.org/clincancerres/article/29/7/1209/718765/Targeting-MDSC-Differentiation-Using-ATRA-A-Phase
Mar 2023
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The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis

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1. scibot 02 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112165
  
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sciencedirect.com/science/article/pii/S2211124723001766
Jul 2022
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https://medrxiv.org/cgi/content/10.1101/2022.01.04.21268586

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1. scibot 15 Jul 2022
  
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  DOI: 10.1101/2022.01.04.21268586
  
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medrxiv.org/content/10.1101/2022.01.04.21268586v1
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

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1. scibot 04 Mar 2022
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.cell.2022.01.029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8810349/
Feb 2022
www.nature.com www.nature.com

Mass cytometry profiling of human dendritic cells in blood and tissues

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1. scibot 23 Feb 2022
  
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  AB_571927
  
  DOI: 10.1038/s41596-021-00599-x
  
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nature.com/articles/s41596-021-00599-x
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Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

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1. scibot 05 Feb 2022
  
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  DOI: 10.1038/s41467-022-28172-4
  
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nature.com/articles/s41467-022-28172-4
Dec 2021
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Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair

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1. scibot 15 Dec 2021
  
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  DOI: 10.1016/j.xpro.2021.101031
  
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sciencedirect.com/science/article/pii/S2666166721007371
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses

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1. scibot 17 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.06.029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8241654/
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T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

1
1. scibot 03 Jul 2021
  
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  RRID:AB_571927
  
  DOI: 10.7554/eLife.67123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8225385/
Jun 2021
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Bifidobacteria-mediated immune system imprinting early in life

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1. scibot 18 Jun 2021
  
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  DOI: 10.1016/j.cell.2021.05.030
  
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sciencedirect.com/science/article/pii/S0092867421006607
Feb 2021
www.frontiersin.org www.frontiersin.org

Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure

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1. scibot 27 Feb 2021
  
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  RRID:AB_571927
  
  DOI: 10.3389/fimmu.2020.574839
  
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frontiersin.org/article/10.3389/fimmu.2020.574839/full
www.cell.com www.cell.com

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

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1. scibot 24 Feb 2021
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.ccell.2020.11.005
  
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  RRID:AB_571927 RRIDCUR:Validated
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cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A distinct innate immune signature marks progression from mild to severe COVID-19

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1. scibot 28 Jan 2021
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.xcrm.2020.100166
  
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  RRID:AB_571927 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7817872/
Sep 2020
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Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity

1
1. scibot 25 Sep 2020
  
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  RRID:AB_571927
  
  DOI: 10.1016/j.celrep.2020.108180
  
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The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells

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Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19

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ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation

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  DOI: 10.1016/j.celrep.2020.02.069
  
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Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells

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Untitled document

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Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy

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