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Tumors exploit interclonal Hedgehog-Wnt crosstalk to drive tumor-promoting cell competition

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  DOI: 10.1016/j.devcel.2026.07.018
  
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54.241.53.176 54.241.53.176

An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

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1. scibot 19 Aug 2026
  
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  DOI: 10.1371/journal.pgen.1011387
  
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54.241.53.176/6d9de9560e18dc1772c142fd048e71fe9aa1ba15/PMID_39226333-html.html
Jul 2026
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Asperous coordinates regeneration timing by regulating damage-induced WNT signaling

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1. scibot 17 Jul 2026
  
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  DOI: 10.1016/j.isci.2026.116823
  
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journal.pgen.1011387.s009-html.html

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54.241.53.176/6baf3e6a8c7a828ab95a4371c54a0422dad9c85f/journal.pgen.1011387.s009-html.html
May 2026
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Bendless-mediated K63 ubiquitination modulates cellular signalling to regulate Drosophila hematopoiesis

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1. scibot 19 May 2026
  
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  DOI: 10.1186/s12964-026-02887-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13173845/
Nov 2025
54.241.53.176 54.241.53.176

Cross-Species Insights from ART-D to Uncover Evolutionarily Conserved Oncogenic Mechanisms

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1. scibot 26 Nov 2025
  
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  DOI: 10.1101/2025.10.20.683390
  
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54.241.53.176/1b85b62c56ae96f2aa62f29a380b5548c688b747/2025.10.20.683390v1.full-html.html
Sep 2025
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Pp1-87B/PPP1CC-JNK axis integrates apoptosis and ferroptosis-like cell death to regulate cell competition and tumorigenesis

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1. scibot 04 Sep 2025
  
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Aug 2025
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zhao-et-al-hemocytes-facilitate-interclonal-cooperation-induced-tumor-malignancy-by-hijacking-the-innate-immune-system-html.html

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1. scibot 27 Aug 2025
  
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  DOI: 10.1038/s44318-025-00547-5
  
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54.241.53.176/7da1eb3af3e6ce644fa025de82baea3bf865997c/Book3-html.html
Jun 2025
52.53.155.43 52.53.155.43

kong-et-al-adipose-tissue-secreted-spz5-promotes-distal-tumor-progression-via-toll-6-mediated-hh-pathway-activation-in-html.html

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52.53.155.43/f797b68cc578c5707d96baf6b2dcdbd6b1b6aadb/kong-et-al-adipose-tissue-secreted-spz5-promotes-distal-tumor-progression-via-toll-6-mediated-hh-pathway-activation-in-html.html
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Adipose tissue-secreted Spz5 promotes distal tumor progression via Toll-6-mediated Hh pathway activation in Drosophila

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1. scibot 28 Jun 2025
  
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embopress.org/doi/10.1038/s44318-025-00489-y
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Macrophages promote tumor growth by phagocytosis-mediated cytokine amplification in Drosophila

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.cub.2025.05.068
  
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Feb 2025
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1-s2.0-S2589004225003086-main-html.html

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112048
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11928871/
Nov 2024
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Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44318-024-00290-3
  
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embopress.org/doi/10.1038/s44318-024-00290-3
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wang-et-al-2024-nuclear-receptor-e75-nr1d2-promotes-tumor-malignant-transformation-by-integrating-hippo-and-notch-html.html

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pmc.ncbi.nlm.nih.gov/articles/PMC11649922/
Aug 2024
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The JNK and Hippo pathways control epithelial integrity and prevent tumor initiation by regulating an overlapping transcriptome

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  DOI: 10.1016/j.cub.2024.07.060
  
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Jul 2024
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A novel injury paradigm in the central nervous system of adult Drosophila: molecular, cellular and functional aspects

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1. scibot 24 Jul 2024
  
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  DOI: 10.1242/dmm.044669
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8214735/
May 2024
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An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

3
1. scibot 29 May 2024
  
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  DOI: 10.1101/2024.03.14.585098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10980049/
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Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114251
  
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sciencedirect.com/science/article/pii/S2211124724005795
Mar 2024
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Xrp1 governs the stress response program to spliceosome dysfunction

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1. scibot 23 Mar 2024
  
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  DOI: 10.1093/nar/gkae055
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954486/
Nov 2023
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Differential Ire1 determines loser cell fate in tumor-suppressive cell competition

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113303
  
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sciencedirect.com/science/article/pii/S2211124723013153
Apr 2023
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Coordinated growth of linked epithelia is mediated by the Hippo pathway

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1. scibot 12 Apr 2023
  
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  DOI: 10.1101/2023.02.26.530099
  
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52.53.155.43/e9974913cd84f9faae90a857e541a21f2c05b84f/2023.02.26.530099v2.full-html.html
Jan 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Specialized cells that sense tissue mechanics to regulate Drosophila morphogenesis

1
1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.devcel.2023.01.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11345685/
Jul 2022
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Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.cub.2022.06.040
  
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sciencedirect.com/science/article/pii/S0960982222010028
Jun 2022
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Fat body-derived Spz5 remotely facilitates tumor-suppressive cell competition through Toll-6-α-Spectrin axis-mediated Hippo activation

1
1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110980
  
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Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila

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  DOI: 10.1016/j.devcel.2022.05.015
  
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sciencedirect.com/science/article/pii/S1534580722003720
May 2022
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Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila

1
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sciencedirect.com/science/article/pii/S2211124722005885
Apr 2022
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Non-apoptotic activation of Drosophila caspase-2/9 modulates JNK signaling, the tumor microenvironment, and growth of wound-like tumors

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  DOI: 10.1016/j.celrep.2022.110718
  
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sciencedirect.com/science/article/pii/S221112472200479X
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

1
1. scibot 30 Nov 2021
  
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  DOI: 10.7554/eLife.67516
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8610493/
Oct 2021
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Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation

1
1. scibot 09 Oct 2021
  
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  DOI: 10.1016/j.devcel.2021.09.015
  
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sciencedirect.com/science/article/pii/S1534580721007334
Jul 2021
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Oncogenic Notch Triggers Neoplastic Tumorigenesis in a Transition-Zone-like Tissue Microenvironment

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1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.devcel.2019.03.015
  
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sciencedirect.com/science/article/pii/S1534580719302266
Nov 2018
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Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation

1
1. scibot 05 Nov 2018
  
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nature.com/articles/ncb3631
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Apical and Basal Matrix Remodeling Control Epithelial Morphogenesis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S153458071830460X
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Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0960982218304500
Nov 2017
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Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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jove.com/video/55901/induction-diagnosis-tumors-drosophila-imaginal-disc