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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Pleiotropic and Functionally Divergent RAC3 Variant Disrupts Neurodevelopment and Impacts Organogenesis

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1. scibot 21 Oct 2025
  
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  RRID:AB_591112
  
  DOI: 10.3390/cells14191499
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12523998/
Jun 2025
www.nature.com www.nature.com

PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

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1. scibot 18 Jun 2025
  
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  RRID: AB_591112
  
  DOI: 10.1038/s41388-025-03468-z
  
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nature.com/articles/s41388-025-03468-z
Apr 2025
www.sciencedirect.com www.sciencedirect.com

RabGAP1L modulates Rab7A and Rab10 to orchestrate cell-autonomous immunity

1
1. scibot 19 Apr 2025
  
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  AB_591112
  
  DOI: 10.1016/j.celrep.2025.115599
  
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sciencedirect.com/science/article/pii/S2211124725003705
Feb 2025
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A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation

1
1. scibot 27 Feb 2025
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.jbc.2025.108346
  
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sciencedirect.com/science/article/pii/S0021925825001954
aacrjournals.org aacrjournals.org

SENP1 decreases RNF168 phase separation to promote DNA damage repair and drug resistance in colon cancer

1
1. scibot 13 Feb 2025
  
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  RRID:AB_591112
  
  DOI: 10.1158/0008-5472.CAN-22-4017
  
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aacrjournals.org/cancerres/article/83/17/2908/728579/SENP1-Decreases-RNF168-Phase-Separation-to-Promote
Jan 2025
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A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification

1
1. scibot 14 Jan 2025
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.jlr.2025.100743
  
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sciencedirect.com/science/article/pii/S0022227525000033
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms

1
1. scibot 22 Dec 2024
  
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  RRID:AB_591112
  
  DOI: 10.3390/cells13232032
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11640247/
Sep 2024
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Pathophysiological significance of the p.E31G variant in RAC1 responsible for a neurodevelopmental disorder with microcephaly

1
1. scibot 26 Sep 2024
  
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  AB_591112
  
  DOI: 10.1016/j.bbadis.2024.167520
  
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sciencedirect.com/science/article/pii/S0925443924005143
Jul 2024
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Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer

1
1. scibot 12 Jul 2024
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.celrep.2024.114487
  
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sciencedirect.com/science/article/pii/S2211124724008167
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions

1
1. scibot 02 Jun 2024
  
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  RRID:AB_591112
  
  DOI: 10.1038/s41467-024-48446-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11133436/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis

1
1. scibot 10 Apr 2024
  
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  RRID:AB_591112
  
  DOI: 10.1038/s41467-024-47289-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10998861/
Aug 2023
52.53.155.43 52.53.155.43

can-22-4017-html.html

2
1. scibot 04 Aug 2023
  
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  RRID:AB_591112
  
  DOI: 10.1158/0008-5472.can-22-4017
  
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2. scibot 04 Aug 2023
  
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  RRID:AB_591112
  
  DOI: 10.1158/0008-5472.CAN-22-4017
  
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52.53.155.43/9095f2133470165b212e6a97c53f24a603903e15/can-22-4017 (1)-html.html
Jul 2023
link.springer.com link.springer.com

Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development

1
1. scibot 08 Jul 2023
  
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  RRID:AB_591112
  
  DOI: 10.1007/s00795-023-00364-x
  
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link.springer.com/article/10.1007/s00795-023-00364-x
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association

1
1. scibot 21 Jun 2023
  
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  RRID:AB_591112
  
  DOI: 10.1038/s41598-023-36381-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10275923/
May 2023
academic.oup.com academic.oup.com

Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes

1
1. scibot 05 May 2023
  
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  RRID:AB_591112
  
  DOI: 10.1093/brain/awac106
  
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academic.oup.com/brain/advance-article/doi/10.1093/brain/awac106/6628315
Apr 2023
www.karger.com www.karger.com

Expression analyses of Rich2/Arhgap44, a Rho family GTPase-activating protein, during mouse brain development

1
1. scibot 21 Apr 2023
  
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  AB_591112
  
  DOI: 10.1159/000529051
  
  Resource: (MBL International Cat# M047-3, RRID:AB_591112)
  
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karger.com/Article/FullText/529051
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Thymidine kinase 1 drives hepatocellular carcinoma in enzyme-dependent and -independent manners

1
1. scibot 19 Apr 2023
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.cmet.2023.03.017
  
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sciencedirect.com/science/article/pii/S1550413123000955
Jan 2023
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hCINAP regulates the differentiation of embryonic stem cells by regulating NEDD4 liquid-liquid phase-separation-mediated YAP1 activation

1
1. scibot 28 Jan 2023
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.celrep.2022.111935
  
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sciencedirect.com/science/article/pii/S2211124722018368
52.53.155.43 52.53.155.43

SSRN-id4189094-html.html

1
1. scibot 06 Jan 2023
  
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  RRID:AB_591112
  
  DOI: 10.2139/ssrn.4189094
  
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52.53.155.43/5871da1393eb1add03cb96eebf51fc601cd15759/SSRN-id4189094-html.html
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival

1
1. scibot 05 Oct 2022
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.celrep.2022.111435
  
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sciencedirect.com/science/article/pii/S2211124722012761
Sep 2022
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S-palmitoylation of tyrosinase at cysteine500 regulates melanogenesis

1
1. scibot 10 Sep 2022
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.jid.2022.08.040
  
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sciencedirect.com/science/article/pii/S0022202X22018929
Jul 2022
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Acetylation of p62 regulates base excision repair through interaction with APE1

1
1. scibot 27 Jul 2022
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.celrep.2022.111116
  
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sciencedirect.com/science/article/pii/S2211124722009226
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Deubiquitinase OTUD6A promotes breast cancer progression by increasing TopBP1 stability and rendering tumor cells resistant to DNA-damaging therapy

1
1. scibot 01 Jul 2022
  
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  RRID:AB_591112
  
  DOI: 10.1038/s41418-022-01036-6
  
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nature.com/articles/s41418-022-01036-6
Jun 2022
jmg.bmj.com jmg.bmj.com

Gain-of-function p.F28S variant in RAC3 disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder

1
1. scibot 18 Jun 2022
  
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  RRID:AB_591112
  
  DOI: 10.1136/jmedgenet-2022-108483
  
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jmg.bmj.com/content/early/2022/05/24/jmedgenet-2022-108483
Apr 2022
www.karger.com www.karger.com

Expression Analyses of Rac3, a Rho Family Small GTPase, during Mouse Brain Development

1
1. scibot 22 Apr 2022
  
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  RRID:AB_591112
  
  DOI: 10.1159/000521168
  
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karger.com/Article/FullText/521168
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes

1
1. scibot 04 Mar 2022
  
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  RRID:AB_591112
  
  DOI: 10.3390/cells11040696
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8870177/
Oct 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 26 Oct 2021
  
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  RRID:AB_591112
  
  DOI: 10.1002/prp2.749
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.749
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An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

1
1. scibot 21 Oct 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.chembiol.2021.10.008
  
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sciencedirect.com/science/article/pii/S2451945621004426
Sep 2021
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Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species

1
1. scibot 18 Sep 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.cmet.2021.08.014
  
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sciencedirect.com/science/article/pii/S1550413121003776
Jun 2021
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OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin

1
1. scibot 22 Jun 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.molcel.2021.05.031
  
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sciencedirect.com/science/article/pii/S1097276521004445
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Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1

1
1. scibot 19 Jun 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.cmet.2021.05.019
  
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sciencedirect.com/science/article/pii/S1550413121002709
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TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

1
1. scibot 09 Jun 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.cmet.2021.05.014
  
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sciencedirect.com/science/article/pii/S155041312100231X
May 2021
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A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis

1
1. scibot 05 May 2021
  
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  RRID:AB_591112
  
  DOI: 10.1016/j.cmet.2021.04.006
  
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sciencedirect.com/science/article/pii/S1550413121001728
Nov 2018
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Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication

1
1. scibot 05 Nov 2018
  
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  RRID:AB_591112
  
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  (MBL International Cat# M047-3, RRID:AB_591112)
  
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sciencedirect.com/science/article/pii/S1931312817305504
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A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size

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1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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europepmc.org/articles/PMC5722641/
Nov 2017
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TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence

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1. scibot 08 Nov 2017
  
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  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S1535610817301617