39 Matching Annotations
  1. Last 7 days
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    Harmine suppresses pancreatic cancer through DYRK1A-mediated hyper-activated RAS/MAPK inhibition
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    sciencedirect.com/science/article/pii/S0006295225005568
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12286604/
  5. Jan 2025
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    DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1534580724007755
  7. Jul 2024
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    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
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    sciencedirect.com/science/article/pii/S2211124724007307
  9. Feb 2024
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    Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875621/
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    Mechanical Netrin-1-DCC Coupling Mediates Netrin-1–induced Axonal Haptotaxis
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    biorxiv.org/content/10.1101/2023.12.03.569828v1
  12. Aug 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility
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    ncbi.nlm.nih.gov/pmc/articles/PMC10438455/
  14. www.science.org www.science.org
    XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility
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    science.org/doi/10.1126/sciadv.adg5211
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    Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis
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    science.org/doi/10.1126/sciadv.adf6895
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    Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403219/
  17. Jun 2023
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    sciencedirect.com/science/article/pii/S2211124723007040
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    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression
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    sciencedirect.com/science/article/pii/S2211124723006654
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15789
  21. May 2023
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    The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy
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    sciencedirect.com/science/article/pii/S1097276523003167
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy–linked E40K mutation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10248865/
  24. Nov 2022
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    Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella
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    sciencedirect.com/science/article/pii/S2211124722015571
  26. Feb 2022
  27. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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    pubmed.ncbi.nlm.nih.gov/35172162/
  28. Aug 2021
  29. www.sciencedirect.com www.sciencedirect.com
    The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S1074761321002521
  30. Jul 2021
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    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
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    embopress.org/doi/full/10.15252/embr.201947728
  32. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
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    elifesciences.org/articles/48318
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    Nuclear translocation promotes proteasomal degradation of human Rad17 protein through the N-terminal destruction boxes
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    sciencedirect.com/science/article/pii/S0021925821006293
  34. Jun 2021
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    Extreme deformability of insect cell membranes is governed by phospholipid scrambling
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    sciencedirect.com/science/article/pii/S2211124721005702
  36. May 2021
  37. elifesciences.org elifesciences.org
    Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay
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    elifesciences.org/articles/66290
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    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
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    sciencedirect.com/science/article/pii/S1931312821001827
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    The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors
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    sciencedirect.com/science/article/pii/S1097276520305025
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    Actin Polymerization and ESCRT Trigger Recruitment of the Fusogens Syntaxin-2 and EFF-1 to Promote Membrane Repair in C. elegans
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    sciencedirect.com/science/article/pii/S1534580720305062
  41. Feb 2021
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    Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia
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    sciencedirect.com/science/article/pii/S0092867420314550
  43. elifesciences.org elifesciences.org
    Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase
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    elifesciences.org/articles/60969
  44. Jan 2021
  45. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
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    sciencedirect.com/science/article/pii/S221112472031620X
  46. Nov 2020
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast
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    ncbi.nlm.nih.gov/pmc/articles/PMC7609059/
  48. Sep 2020
  49. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
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    rupress.org/jcb/article/219/9/e201912144/151863/Critical-role-of-mitochondrial-ubiquitination-and
  50. Jan 2020
  51. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers
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    sciencedirect.com/science/article/pii/S1931312819304196
  52. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718320813
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    Untitled document
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    sciencedirect.com/science/article/pii/S1534580719302990
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6361614/
  55. Nov 2018
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6080949/
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    NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
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    sciencedirect.com/science/article/pii/S1097276517307931
  58. Nov 2017
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    TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence
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    sciencedirect.com/science/article/pii/S1535610817301617