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  1. Last 7 days
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    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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    sciencedirect.com/science/article/pii/S1097276524003290
  3. Apr 2024
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    The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
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    sciencedirect.com/science/article/pii/S1534580724002284
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    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    link.springer.com/article/10.1038/s41594-024-01294-7
  6. Feb 2024
  7. www.biorxiv.org www.biorxiv.org
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    1. scibot 15 Feb 2024
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      DOI: 10.1101/2023.12.20.572718

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    biorxiv.org/content/10.1101/2023.12.20.572718v1
  8. Jan 2024
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    The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo
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    sciencedirect.com/science/article/pii/S2211124723016625
  10. Dec 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  12. Jun 2023
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    Identification of XAF1 as an endogenous AKT inhibitor
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    sciencedirect.com/science/article/pii/S2211124723007015
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    sciencedirect.com/science/article/pii/S2211124723007040
  15. Feb 2023
  16. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
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    nature.com/articles/s41467-023-36058-2
  17. Nov 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    sciencedirect.com/science/article/pii/S2211124722015297
  19. Mar 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass
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    1. scibot 09 Mar 2022
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    sciencedirect.com/science/article/pii/S1097276522001393
  21. Jan 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase
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    sciencedirect.com/science/article/pii/S2589004221016205
  23. Oct 2021
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    1. scibot 21 Oct 2021
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    sciencedirect.com/science/article/pii/S2211124721013371
  25. Aug 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
  27. www.sciencedirect.com www.sciencedirect.com
    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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    1. scibot 07 Aug 2021
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    sciencedirect.com/science/article/pii/S0092867418315162
  28. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1097276518309857
  29. europepmc.org europepmc.org
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      DOI: 10.7554/eLife.38771

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    europepmc.org/articles/PMC6037479/
  30. Jul 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6202423/
  32. rupress.org rupress.org
    Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination
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    1. scibot 23 Jul 2021
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      DOI: 10.1083/jcb.202006043

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    rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
  33. Jun 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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    sciencedirect.com/science/article/pii/S2211124721005635
  35. Mar 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling
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      RRID:AB_61093

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    sciencedirect.com/science/article/pii/S1097276521000095
  37. Jan 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
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    1. scibot 27 Jan 2021
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    sciencedirect.com/science/article/pii/S2211124720316697
  39. Oct 2020
  40. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Proximity Ligation Assay for Detecting Protein‐Protein Interactions and Protein Modifications in Cells and Tissues in Situ
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      DOI: 10.1002/cpcb.115

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpcb.115
  41. Sep 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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      DOI: 10.1016/j.stem.2019.12.006

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    sciencedirect.com/science/article/pii/S1934590919305247
  43. Jan 2020
  44. www.sciencedirect.com www.sciencedirect.com
    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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      DOI: 10.1016/j.chembiol.2019.11.004

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    sciencedirect.com/science/article/pii/S2451945619303629
  45. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
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      DOI: 10.7554/eLife.44502

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    elifesciences.org/articles/44502
  46. www.sciencedirect.com www.sciencedirect.com
    ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response
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      DOI: 10.1016/j.celrep.2019.09.008

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    sciencedirect.com/science/article/pii/S2211124719311854
  47. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718319570
  48. Nov 2018
  49. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1097276518306804
  50. academic.oup.com academic.oup.com
    Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling
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    academic.oup.com/endo/article/159/8/2966/5035244
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6037479/
  52. www.jneurosci.org www.jneurosci.org
    USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-dependent Protein Levels
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    1. scibot 05 Nov 2018
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    jneurosci.org/content/38/23/5289
  53. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
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    europepmc.org/articles/PMC5663478/
  54. academic.oup.com academic.oup.com
    Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response
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    academic.oup.com/endo/article/158/11/4000/4093568
  55. Nov 2017
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5640506/
  57. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
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    1. scibot 08 Nov 2017
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    sciencedirect.com/science/article/pii/S1097276517306172
  58. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
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    sciencedirect.com/science/article/pii/S1097276517306184