285 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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    1. scibot 14 Nov 2024
      RRID:AB_621847

      DOI: 10.1016/j.cub.2024.10.061

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    sciencedirect.com/science/article/pii/S096098222401457X
  3. Sep 2024
  4. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry
    1
    1. scibot 27 Sep 2024
      RRID:AB_621847

      DOI: 10.1096/fj.202302501RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302501RR
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses
    1
    1. scibot 25 Sep 2024
      RRID:AB_10715072

      DOI: 10.7554/eLife.53406

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    ncbi.nlm.nih.gov/pmc/articles/PMC6984820/
  6. www.sciencedirect.com www.sciencedirect.com
    IRTKS (BAIAP2L1) Elongates Epithelial Microvilli Using EPS8-Dependent and Independent Mechanisms
    1
    1. scibot 25 Sep 2024
      RRID:AB_62184

      DOI: 10.1016/j.cub.2018.07.022

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    sciencedirect.com/science/article/pii/S0960982218309217
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fetal sex and the relative reactivity of human umbilical vein and arteries are key determinants in potential beneficial effects of phosphodiesterase inhibitors
    1
    1. scibot 06 Sep 2024
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      DOI: 10.1152/japplphysiol.00540.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC11365547/
  8. Aug 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
    1
    1. scibot 21 Aug 2024
      RRID:AB_621847

      DOI: 10.1083/jcb.202305003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857907/
  10. 52.53.155.43 52.53.155.43
    nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html
    1
    1. scibot 20 Aug 2024
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      DOI: 10.25833/g4qt-3356

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    52.53.155.43/b68deb9c62e0885cf46c9d0e6108ed17561f8fea/nemeth-et-al-2024-adiponectin-suppresses-stiffness-dependent-pro-fibrotic-activation-of-lung-fibroblasts-html.html
  11. www.sciencedirect.com www.sciencedirect.com
    The FXR1 network acts as a signaling scaffold for actomyosin remodeling
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.015

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    sciencedirect.com/science/article/pii/S009286742400775X
  12. Jul 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of small molecule inhibitors of G3BP-driven stress granule formation
    1
    1. scibot 30 Jul 2024
      RRID:AB_621847

      DOI: 10.1083/jcb.202308083

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    ncbi.nlm.nih.gov/pmc/articles/PMC10824102/
  14. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017851-main-html.html
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    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.isci.2024.110560

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    52.53.155.43/28f1f0cd51770599356cfb72d036c0e468b38b34/1-s2.0-S2589004224017851-main-html.html
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    Swi/Snf chromatin remodeling regulates transcriptional interference and gene repression
    1
    1. scibot 25 Jul 2024
      AB_621847

      DOI: 10.1016/j.molcel.2024.06.029

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    sciencedirect.com/science/article/pii/S1097276524005367
  16. www.cell.com www.cell.com
    Monitoring melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance
    1
    1. scibot 23 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101611

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00315-X
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective targeting of mu opioid receptors to primary cilia
    1
    1. scibot 20 Jul 2024
      RRID:AB_621847

      DOI: 10.1016/j.celrep.2024.114164

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257377/
  18. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.molcel.2024.06.006

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    sciencedirect.com/science/article/pii/S1097276524004842
  19. www.cell.com www.cell.com
    Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure
    1
    1. scibot 19 Jul 2024
      RRID:AB_621847

      DOI: 10.1016/j.celrep.2024.114395

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    cell.com/cell-reports/fulltext/S2211-1247(24)00723-X
  20. www.cell.com www.cell.com
    Reproductive regulation of the mitochondrial stress response in Caenorhabditis elegans
    1
    1. scibot 18 Jul 2024
      RRID:AB_621847

      DOI: 10.1016/j.celrep.2024.114336

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    cell.com/cell-reports/abstract/S2211-1247(24)00664-8
  21. www.sciencedirect.com www.sciencedirect.com
    CCAR1 promotes DNA repair via alternative splicing
    1
    1. scibot 18 Jul 2024
      RRID:AB_621847

      DOI: 10.1016/j.molcel.2024.06.011

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    sciencedirect.com/science/article/pii/S1097276524005148
  22. www.sciencedirect.com www.sciencedirect.com
    Evolution of ion transporter Na+/K+-ATPase expression in the osmoregulatory maxillary glands of an invasive copepod
    1
    1. scibot 18 Jul 2024
      RRID:AB_621847

      DOI: 10.1016/j.isci.2024.110278

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    sciencedirect.com/science/article/pii/S2589004224015037
  23. www.biorxiv.org www.biorxiv.org
    An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation
    1
    1. scibot 16 Jul 2024
      RRID:AB_621847

      DOI: 10.1101/2024.07.08.602551

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    biorxiv.org/content/10.1101/2024.07.08.602551v1
  24. www.sciencedirect.com www.sciencedirect.com
    The hydrophobicity of the CARD8 N-terminus tunes inflammasome activation
    1
    1. scibot 11 Jul 2024
      AB_621847

      DOI: 10.1016/j.chembiol.2024.06.004

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    sciencedirect.com/science/article/pii/S245194562400223X
  25. Jun 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
    1
    1. scibot 07 Jun 2024
      LI-COR BiosciencesCat#926-32212

      DOI: 10.1016/j.cell.2024.05.001

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    sciencedirect.com/science/article/pii/S0092867424004914
  27. Apr 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of human centromeric arrays in cells undergoing break-induced replication
    1
    1. scibot 30 Apr 2024
      RRID:AB_621847

      DOI: 10.1016/j.celrep.2024.113851

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034957/
  29. www.sciencedirect.com www.sciencedirect.com
    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
    1
    1. scibot 20 Apr 2024
      RRID:AB_621847

      DOI: 10.1016/j.devcel.2024.03.032

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    sciencedirect.com/science/article/pii/S1534580724002004
  30. www.sciencedirect.com www.sciencedirect.com
    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
    1
    1. scibot 11 Apr 2024
      LicorCAT#926-32212

      DOI: 10.1016/j.xgen.2024.100537

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    sciencedirect.com/science/article/pii/S2666979X24000934
  31. www.sciencedirect.com www.sciencedirect.com
    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.004

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    sciencedirect.com/science/article/pii/S1934590924000857
  32. Mar 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1083/jcb.202307092

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959120/
  34. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.037

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    sciencedirect.com/science/article/pii/S1097276524001801
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of meiotic entry by dual inhibition of a key mitotic transcription factor
    1
    1. scibot 16 Mar 2024
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      DOI: 10.7554/eLife.90425

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    ncbi.nlm.nih.gov/pmc/articles/PMC10939502/
  36. Feb 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113740

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    sciencedirect.com/science/article/pii/S2211124724000688
  38. 52.53.155.43 52.53.155.43
    RAS isoform specific activities are disrupted by disease associated mutations during cell differentiation
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      DOI: 10.1101/2023.10.05.561021

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    52.53.155.43/19126de606c776a10e00c0c9a385ef3636eaaf16/2023.10.05.561021v2.full (1)-html.html
  39. 52.53.155.43 52.53.155.43
    Identification of an H-Ras nanocluster disrupting peptide
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      DOI: 10.1101/2023.09.07.556635

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      DOI: 10.1101/2023.09.07.556635

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    52.53.155.43/50febc729cb1f3f2f29f241e3592121bf7d8fba9/2023.09.07.556635v1.full-html.html
  40. 52.53.155.43 52.53.155.43
    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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      DOI: 10.1101/2023.08.23.554263

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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
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    Sound-evoked adenosine release in cooperation with neuromodulatory circuits permits auditory cortical plasticity and perceptual learning
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      DOI: 10.1016/j.celrep.2024.113758

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    sciencedirect.com/science/article/pii/S2211124724000871
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    C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line
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      DOI: 10.1016/j.molcel.2024.01.014

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      DOI: 10.1016/j.molcel.2024.01.014

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    sciencedirect.com/science/article/pii/S1097276524000509
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
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      DOI: 10.1016/j.isci.2024.108907

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839966/
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    Hydroxypyridone anti-fungals selectively induce myofibroblast apoptosis in an in vitro model of hypertrophic scars
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      DOI: 10.1016/j.ejphar.2024.176369

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    sciencedirect.com/science/article/pii/S0014299924000578
  45. Jan 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Live-cell imaging defines a threshold in CDK activity at the G2/M transition
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      DOI: 10.1016/j.devcel.2023.12.014

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    Transient anticonvulsant effects of time-restricted feeding in the 6-Hz mouse model
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    Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
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  49. Dec 2023
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    Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry
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    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors
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    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
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    Universal features of Nsp1-mediated translational shutdown by coronaviruses
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    The transcriptional regulator Ume6 is a major driver of early gene expression during gametogenesis
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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    A Zpr1 co-chaperone mediates folding of eukaryotic translation elongation factor 1A via a GTPase cycle
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    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
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    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
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    52.53.155.43/7a1276d45430138c9432ff25359932d8ef5aed01/British J Pharmacology - 2023 - Mazzotta - BQ788 Reveals Glial ETBR Modulation of Neuronal Cholinergic and Nitrergic-html.html
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    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
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    The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
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    APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
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    Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
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    The Transcriptional Regulator Ume6 is a Major Driver of Early Gene Expression during Gametogenesis
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    Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus
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    C9ORF72 suppresses JAK-STAT mediated inflammation
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    MeCP2 Represses the Activity of Topoisomerase IIβ in Long Neuronal Genes
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain
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  95. Mar 2023
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD
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    Transient receptor potential canonical type 6 (TRPC6) O-GlcNAcylation at Threonine-221 plays potent role in channel regulation
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    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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    Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line
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    N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on α-dystroglycan and prevents muscular dystrophy
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    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
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    SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS
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  105. Jan 2023
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    Microglial reprogramming by Hv1 antagonism protects neurons from inflammatory and glutamate toxicity
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    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
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    Vitamin B12 deficiency induces glucose intolerance, delays peak insulin levels and promotes ketogenesis in female rats
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    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    Zinc-finger protein Zpr1 is a bespoke chaperone essential for eEF1A biogenesis
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  112. Dec 2022
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    Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization
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    Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT
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    The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation
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  116. Nov 2022
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    TES-1/Tes and ZYX-1/Zyxin protect junctional actin networks under tension during epidermal morphogenesis in the C. elegans embryo
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    Phenotypic screening identifies hydroxypyridone anti-fungals as novel medicines for the prevention of hypertrophic scars
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  119. Oct 2022
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    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein
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    Selenium modulates cancer cell response to pharmacologic ascorbate
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  122. Sep 2022
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    Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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    Vaccination-based immunotherapy to target profibrotic cells in liver and lung
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    Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    From guide to guard—activation mechanism of the stress-sensing chaperone Get3
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    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
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    Context-dependent regulation of ferroptosis sensitivity
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    Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila
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    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    Antigenic and virological properties of an H3N2 variant that continues to dominate the 2021–22 Northern Hemisphere influenza season
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  137. May 2022
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    Non-canonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemiaNovel non-canonical function of AGO2 in T-PLL
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    Aging Alters the Formation and Functionality of Signaling Microdomains Between L-type Calcium Channels and β2-Adrenergic Receptors in Cardiac Pacemaker Cells
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    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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  141. Apr 2022
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    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
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    Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function
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    Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock
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  145. Mar 2022
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    Linkage reprogramming by tailor-made E3s reveals polyubiquitin chain requirements in DNA-damage bypass
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    Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3
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  149. Feb 2022
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    A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing
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    Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A
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  154. Jan 2022
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    Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons
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  156. Dec 2021
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    Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1
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  160. Nov 2021
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    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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    Programmed cortical ER collapse drives selective ER degradation and inheritance in yeast meiosis
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  164. Oct 2021
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    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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    Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability
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    c-FOS drives reversible basal to squamous cell carcinoma transition
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    SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
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  169. Sep 2021
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    Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing
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    Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
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  173. Aug 2021
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    Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
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    Quantitative live-cell imaging and computational modeling shed new light on endogenous WNT/CTNNB1 signaling dynamics
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    A fluorescent reporter assay of differential gene expression response to insulin in hepatocytes
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    Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation
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    Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis
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  182. Jul 2021
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    Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events
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    Pathogenic <i>FAM83G</i> palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
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      IRDye 800CW Donkey anti-Mouse IgG

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
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    Menin Associates with the Mitotic Spindle and is Important for Cell Division
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    Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signaling
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  191. www.nature.com www.nature.com
    Quantification of phosphoinositides reveals strong enrichment of PIP 2 in HIV-1 compared to producer cell membranes
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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Aspirin upregulates Suppressor of Cytokine Signaling 3 in glial cells via PPARα
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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model
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  194. Jun 2021
  195. www.sciencedirect.com www.sciencedirect.com
    NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
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    Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles
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  198. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response
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  199. May 2021
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    NADPH Oxidase 5 and Melatonin: Involvement in Ram Sperm Capacitation
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    α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology
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    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy
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    Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex
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    Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease
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  207. Apr 2021
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    The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions
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    β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors
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    Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
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    Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression
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    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
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  213. Mar 2021
  214. journals.sagepub.com journals.sagepub.com
    Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain - Ariel Diaz, Paola Merino, Patrick McCann, Manuel A Yepes, Laura G Quiceno, Enrique Torre, Amelia Tomkins, Xiaodong Zhang, Chadwick M Hales, Frank C Tong, Manuel Yepes, 2021
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      IRDye 800CW donkey anti-mouse

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    Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
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  216. elifesciences.org elifesciences.org
    In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates
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    SUMO is a pervasive regulator of meiosis
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    Optic nerve regeneration screen identifies multiple genes restricting adult neural repair
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    The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types
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    MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage
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    Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
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  222. Feb 2021
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    Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis
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  224. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deficiency of Meis1, a transcriptional regulator, in mice and worms: neurochemical and behavioral characterizations with implications in the restless legs syndrome
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    A fluorescent reporter assay of differential gene expression response to insulin in hepatocytes
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    TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47
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    Neuronal non-CG methylation is an essential target for MeCP2 function
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  228. Jan 2021
  229. www.micropublication.org www.micropublication.org
    Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis
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  230. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cilium Axoneme Internalization and Degradation in Chytrid Fungi
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    TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei
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  232. Nov 2020
  233. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation
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    Cerebellum-Specific Deletion of the GABAA Receptor δ Subunit Leads to Sex-Specific Disruption of Behavior
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    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
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    1. scibot 05 Nov 2020
      RRID:AB_621847

      DOI: 10.1016/j.cell.2020.10.030

      Resource: (LI-COR Biosciences Cat# 926-32212, RRID:AB_621847)

      Curator: @evieth

      SciCrunch record: RRID:AB_621847

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      RRID:AB_621847 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7584921/
  237. Oct 2020
  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan
    1
    1. scibot 24 Oct 2020
      RRID:AB_621847

      DOI: 10.7554/eLife.61388

      Resource: (LI-COR Biosciences Cat# 926-32212, RRID:AB_621847)

      Curator: @evieth

      SciCrunch record: RRID:AB_621847

      What is this?
      RRIDCUR:Validated RRID:AB_621847
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556876/
  239. Sep 2020
  240. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant
    1
    1. scibot 26 Sep 2020
      RRID:AB_621847

      DOI: 10.1016/j.celrep.2020.108131

      Resource: (LI-COR Biosciences Cat# 926-32212, RRID:AB_621847)

      Curator: @Naa003

      SciCrunch record: RRID:AB_621847

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      RRIDCUR:Validated RRID:AB_621847
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    pubmed.ncbi.nlm.nih.gov/32937126/
  241. www.sciencedirect.com www.sciencedirect.com
    Involvement of progesterone and estrogen receptors in the ram sperm acrosome reaction
    1
    1. scibot 25 Sep 2020
      RRID:AB_621847

      DOI: 10.1016/j.domaniend.2020.106527

      Resource: (LI-COR Biosciences Cat# 926-32212, RRID:AB_621847)

      Curator: @Naa003

      SciCrunch record: RRID:AB_621847

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      RRIDCUR:Validated RRID:AB_621847
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    sciencedirect.com/science/article/pii/S0739724020300941