59 Matching Annotations
  1. Last 7 days
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    Hyperoside protects against poly-GR-mediated neurodegeneration via regulation of mitochondrial fission and oxidative stress in C9orf72-associated ALS
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    pmc.ncbi.nlm.nih.gov/articles/PMC13235191/
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    Suppression of ATM kinase signaling accelerates cellular senescence
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    sciencedirect.com/science/article/pii/S2213671126001670
  4. May 2026
  5. link.springer.com link.springer.com
    Eugenol Mitigates Mercuric Chloride–Induced Renal Injury by Attenuating Oxidative Stress, Ferroptosis, ER Stress, Apoptosis, and Autophagy
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    link.springer.com/article/10.1007/s12011-026-05115-4
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    Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02340-z
  7. Apr 2026
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    QW-5-70 targets the colchicine site and demonstrates antitumor activity in P-gp–overexpressing cancer models
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    aacrjournals.org/mct/article/doi/10.1158/1535-7163.MCT-25-1013/784192/QW-5-70-Targets-the-Colchicine-Site-and
  9. Nov 2025
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    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    sciencedirect.com/science/article/pii/S1097276525008913
  11. Oct 2025
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  13. Sep 2025
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    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  15. May 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JNK1 inhibitors target distal B cell receptor signaling and overcome BTK-inhibitor resistance in CLL
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    pmc.ncbi.nlm.nih.gov/articles/PMC11586660/
  17. Dec 2024
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fingolimod Inhibits C6 Rat Glioma Proliferation and Migration, Induces Sub-G1 Cell Cycle Arrest, Mitochondrial and Extrinsic Apoptosis In Vitro and Reduces Tumour Growth In Vivo
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    onlinelibrary.wiley.com/doi/10.1111/1440-1681.70012
  19. Sep 2024
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    Synergistic Anti-tumorigenic Effect of Diosmetin in Combination with 5-Fluorouracil on Human Colon Cancer Xenografts in Nude Mice
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    sciencedirect.com/science/article/pii/S0006291X24012130
  21. Aug 2024
  22. www.mdpi.com www.mdpi.com
    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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    mdpi.com/1422-0067/22/24/13398/htm
  23. Jul 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
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    sciencedirect.com/science/article/pii/S2451945624002745
  25. Apr 2024
  26. 52.53.155.43 52.53.155.43
    TSPYL2 induces renal ischemia-reperfusion injury through SREBP-2/ACMSD signaling
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  27. Mar 2024
  28. www.futuremedicine.com www.futuremedicine.com
    Epigenetic disruption of histone deacetylase-2 accelerated apoptotic signaling and retarded malignancy in gastric cells
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    futuremedicine.com/doi/10.2217/epi-2023-0350
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    sciencedirect.com/science/article/pii/S2666379123005591
  31. Sep 2023
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    A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium
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    Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge
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    ncbi.nlm.nih.gov/pmc/articles/PMC10512556/
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    Early protection against bone stress injuries by mobilization of endogenous targeted bone remodeling
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  35. Aug 2023
  36. 52.53.155.43 52.53.155.43
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  37. Jul 2023
  38. dx.doi.org dx.doi.org
    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis
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  42. May 2023
  43. 52.53.155.43 52.53.155.43
    A novel EGFR Inhibitor, HNPMI regulates apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in colon cancer
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    52.53.155.43/b51f94c49df43022b2f6198ee4b9b06582c4cb71/British J Pharmacology - 2023 - Kandhavelu - A novel EGFR Inhibitor HNPMI regulates apoptosis and oncogenesis by-html.html
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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  46. Sep 2022
  47. www.tandfonline.com www.tandfonline.com
    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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    tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
  48. Aug 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke
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  50. Apr 2022
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    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    sciencedirect.com/science/article/pii/S0092867422003403
  53. Mar 2022
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GABA-containing compound gammapyrone protects against brain impairments in Alzheimer’s disease model male rats and prevents mitochondrial dysfunction in cell culture
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24396
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    F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells
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    sciencedirect.com/science/article/pii/S0041008X22001181
  56. Jan 2022
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    Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro
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    sciencedirect.com/science/article/pii/S0891584922000223
  58. Dec 2021
  59. link.springer.com link.springer.com
    Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis
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    link.springer.com/article/10.1186/s12906-019-2456-1
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15720
  61. Nov 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC8584852/
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    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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    sciencedirect.com/science/article/pii/S2211124721014078
  64. Aug 2021
  65. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14537
  68. Jun 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Protective effects of Da-cheng-qi decoction in rats with intracerebral hemorrhage
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    sciencedirect.com/science/article/pii/S0944711321001732
  70. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy
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    sciencedirect.com/science/article/pii/S0028390820303944
  73. Apr 2021
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    From the gut to the heart: L. plantarum and inulin administration as a novel approach to control cardiac apoptosis via 5-HT2B and TrkB receptors in diabetes
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    sciencedirect.com/science/article/pii/S026156142030220X
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    A selective p53 activator and anticancer agent to improve colorectal cancer therapy
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  76. Mar 2021
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  78. Dec 2020
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC7700684/
  80. Sep 2020
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    CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs
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  82. Jan 2020
  83. link.springer.com link.springer.com
    Autophagy as a consequence of seasonal functions of testis and epididymis in adult male European bison ( Bison bonasus, Linnaeus 1758)
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    Klotho-mediated changes in the expression of Atg13 alter formation of ULK1 complex and thus initiation of ER- and Golgi-stress response mediated autophagy
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    link.springer.com/article/10.1007/s10495-019-01579-z
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    Three kinds of corneal host cells contribute differently to corneal neovascularization
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    sciencedirect.com/science/article/pii/S2352396419303275
  88. Nov 2018
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    A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network
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    Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    sciencedirect.com/science/article/pii/S1535610817305020
  92. Nov 2017
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC5127641/
  94. academic.oup.com academic.oup.com
    Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis
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    academic.oup.com/endo/article/158/6/1612/3072148/Aberrant-TGF-Signaling-Drives-Castration-Resistant
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    Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation
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    journals.plos.org/plosone/article