Hypothesis

15 Matching Annotations

Aug 2026
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Inhibitory TIGIT signaling is dependent on T cell receptor activation

1
1. scibot 08 Aug 2026
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.celrep.2026.117787
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
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sciencedirect.com/science/article/pii/S221112472600865X
Jun 2026
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Design optimization of antibody-ligand motifs to enhance CAR-T redirection activity against solid tumors

1
1. scibot 26 Jun 2026
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.xcrm.2026.102885
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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sciencedirect.com/science/article/pii/S2666379126003022
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PD-1 suppresses CAR signaling by forming the inhibitory signalosome colocalizing to CAR microclusters

1
1. scibot 04 Feb 2026
  
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  RRID:AB_627020
  
  DOI: 10.1038/s42003-025-09415-8
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12855910/
Oct 2025
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Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs

1
1. scibot 08 Oct 2025
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.molcel.2025.09.005
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276525007464
Jul 2025
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Human brain vascular multi-omics elucidates disease-risk associations

1
1. scibot 29 Jul 2025
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.neuron.2025.07.001
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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sciencedirect.com/science/article/pii/S0896627325005082
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function

1
1. scibot 02 Apr 2025
  
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  RRID:AB_627020
  
  DOI: 10.1158/2767-9764.CRC-24-0125
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11955954/
Aug 2024
www.cell.com www.cell.com

Calcineurin is an adaptor required for assembly of the TCR signaling complex

1
1. scibot 18 Aug 2024
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.celrep.2024.114568
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
www.mdpi.com www.mdpi.com

Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells

1
1. scibot 02 Aug 2024
  
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  1239
  
  DOI: 10.3390/vaccines9121446
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627020
  
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  RRID:AB_627020 RRIDCUR:Missing
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mdpi.com/2076-393X/9/12/1446/htm
May 2024
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Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity

1
1. scibot 17 May 2024
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.chembiol.2024.04.005
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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  RRID:AB_627020
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sciencedirect.com/science/article/pii/S2451945624001673
Feb 2024
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Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity

1
1. scibot 13 Feb 2024
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.xcrm.2024.101422
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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sciencedirect.com/science/article/pii/S2666379124000454
Oct 2023
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Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer

1
1. scibot 14 Oct 2023
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.xcrm.2023.101224
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
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  SciCrunch record: RRID:AB_627020
  
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sciencedirect.com/science/article/pii/S2666379123003981
May 2023
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Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

1
1. scibot 27 May 2023
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.ccell.2023.04.016
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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  RRID:AB_627020
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sciencedirect.com/science/article/pii/S1535610823001423
Mar 2022
www.cell.com www.cell.com

Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility

1
1. scibot 18 Mar 2022
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.molcel.2022.02.017
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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  RRID:AB_627020
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cell.com/molecular-cell/fulltext/S1097-2765(22)00155-1
Jul 2021
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Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

1
1. scibot 14 Jul 2021
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.celrep.2021.109375
  
  Resource: (Santa Cruz Biotechnology Cat# sc-1239, RRID:AB_627020)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_627020
  
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  RRID:AB_627020
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sciencedirect.com/science/article/pii/S2211124721007737
Sep 2020
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Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy

1
1. scibot 26 Sep 2020
  
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  RRID:AB_627020
  
  DOI: 10.1016/j.cell.2020.07.018
  
  Resource: AB_627020
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_627020
  
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  RRIDCUR:Validated RRID:AB_627020
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RRIDCUR:Validated

RRID:AB_627020

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scibot

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sciencedirect.com/science/article/pii/S0092867420308837