23 Matching Annotations
  1. Jan 2026
  2. www.nature.com www.nature.com
    CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
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    nature.com/articles/s41467-025-67865-4
  3. Dec 2025
  4. www.nature.com www.nature.com
    CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen
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    nature.com/articles/s41523-025-00851-7
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PatientProfiler: building patient-specific signaling models from proteogenomic data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12672659/
  6. Sep 2025
  7. www.sciencedirect.com www.sciencedirect.com
    A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1534580725005301
  8. Aug 2025
  9. www.sciencedirect.com www.sciencedirect.com
    A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision
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    sciencedirect.com/science/article/pii/S109727652500646X
  10. Apr 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasticity of mitotic cyclins in promoting the G2–M transition
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980681/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  14. Feb 2025
  15. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
  16. Apr 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10985479/
  18. Mar 2024
  19. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    sciencedirect.com/science/article/pii/S1097276524001291
  20. Aug 2023
  21. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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    sciencedirect.com/science/article/pii/S0092867423005329
  24. Feb 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9893022/
  26. Aug 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
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    ncbi.nlm.nih.gov/pmc/articles/PMC9403329/
  28. Nov 2021
  29. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  30. Jul 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
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    sciencedirect.com/science/article/pii/S0092867418312637
  32. Jun 2021
  33. www.nature.com www.nature.com
    The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
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    nature.com/articles/s41467-021-23550-w
  34. Sep 2020
  35. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors
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    clincancerres.aacrjournals.org/content/26/12/2997
  36. Nov 2018
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5788747/
  38. www.sciencedirect.com www.sciencedirect.com
    SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage
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    sciencedirect.com/science/article/pii/S0960982217316536
  39. Nov 2017
  40. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers
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    sciencedirect.com/science/article/pii/S1535610817301009