205 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion
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    1. scibot 11 Apr 2024
      RRID:AB_627678

      DOI: 10.1101/2024.03.11.583978

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979924/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NEK2 Promotes Chemosensitivity and Reduces KSHV-positive Primary Effusion Lymphoma Burden
    1
    1. scibot 11 Apr 2024
      RRID:AB_627678

      DOI: 10.1158/2767-9764.CRC-23-0430

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    ncbi.nlm.nih.gov/pmc/articles/PMC11003453/
  4. Mar 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
    1
    1. scibot 22 Mar 2024
      RRID:AB_627678

      DOI: 10.1016/j.isci.2024.109417

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    ncbi.nlm.nih.gov/pmc/articles/PMC10952034/
  6. www.sciencedirect.com www.sciencedirect.com
    Identification of key immune cells infiltrated in lung adenocarcinoma microenvironment and their related lncRNA
    2
    1. scibot 07 Mar 2024
      RRID:AB_627678

      DOI: 10.1016/j.isci.2024.109220

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    2. scibot 06 Mar 2024
      RRID:AB_627678

      DOI: 10.1016/j.isci.2024.109220

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    sciencedirect.com/science/article/pii/S2589004224004413
  7. Feb 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
    1
    1. scibot 16 Feb 2024
      RRID:AB_627678

      DOI: 10.1158/1535-7163.MCT-22-0627

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866396/
  9. elifesciences.org elifesciences.org
    Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    1
    1. scibot 03 Feb 2024
      RRID:AB_627678

      DOI: 10.7554/eLife.89176

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    elifesciences.org/articles/89176
  10. Jan 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells
    1
    1. scibot 26 Jan 2024
      AB_627678

      DOI: 10.1186/s13148-023-01477-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
  12. www.sciencedirect.com www.sciencedirect.com
    Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair
    1
    1. scibot 09 Jan 2024
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113656

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    sciencedirect.com/science/article/pii/S2211124723016674
  13. www.sciencedirect.com www.sciencedirect.com
    Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants
    1
    1. scibot 09 Jan 2024
      RRID:AB_627678

      DOI: 10.1016/j.cell.2023.12.026

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    sciencedirect.com/science/article/pii/S0092867423014009
  14. Dec 2023
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
    1
    1. scibot 29 Dec 2023
      RRID:AB_627678

      DOI: 10.1002/advs.202305620

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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  16. www.mdpi.com www.mdpi.com
    The Cysteine Protease Legumain Is Upregulated by Vitamin D and Is a Regulator of Vitamin D Metabolism in Mice
    1
    1. scibot 29 Dec 2023
      RRID:AB_627678

      DOI: 10.3390/cells13010036

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    mdpi.com/2073-4409/13/1/36
  17. www.sciencedirect.com www.sciencedirect.com
    FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression
    1
    1. scibot 21 Dec 2023
      RRID:AB_627678

      DOI: 10.1016/j.isci.2023.108580

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    sciencedirect.com/science/article/pii/S2589004223026573
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
    1
    1. scibot 28 Nov 2023
      RRID:AB_627678

      DOI: 10.1016/j.isci.2023.108399

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    sciencedirect.com/science/article/pii/S2589004223024768
  20. www.sciencedirect.com www.sciencedirect.com
    Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization
    1
    1. scibot 28 Nov 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113430

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    sciencedirect.com/science/article/pii/S2211124723014420
  21. Oct 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune evasion and membrane fusion of SARS-CoV-2 XBB subvariants EG.5.1 and XBB.2.3
    1
    1. scibot 31 Oct 2023
      RRID:AB_627678

      DOI: 10.1080/22221751.2023.2270069

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    ncbi.nlm.nih.gov/pmc/articles/PMC10606793/
  23. www.sciencedirect.com www.sciencedirect.com
    Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
    1
    1. scibot 28 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.cell.2023.09.024

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    sciencedirect.com/science/article/pii/S0092867423010784
  24. www.sciencedirect.com www.sciencedirect.com
    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
    1
    1. scibot 28 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113123

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    sciencedirect.com/science/article/pii/S221112472301135X
  25. www.sciencedirect.com www.sciencedirect.com
    N6-methyladenosine modification promotes hepatocarcinogenesis through circ-CDYL-enriched and EpCAM-positive liver tumor-initiating exosomes
    1
    1. scibot 17 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.isci.2023.108022

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    sciencedirect.com/science/article/pii/S2589004223020990
  26. www.sciencedirect.com www.sciencedirect.com
    ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation
    1
    1. scibot 14 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.molcel.2023.09.018

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    sciencedirect.com/science/article/abs/pii/S1097276523007402
  27. www.sciencedirect.com www.sciencedirect.com
    Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport
    1
    1. scibot 13 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.devcel.2023.08.030

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    sciencedirect.com/science/article/pii/S1534580723004458
  28. www.embopress.org www.embopress.org
    Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
    1
    1. scibot 13 Oct 2023
      RRID:AB_627678

      DOI: 10.15252/embr.202357912

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    embopress.org/doi/full/10.15252/embr.202357912
  29. www.sciencedirect.com www.sciencedirect.com
    Continued evasion of neutralizing antibody response by Omicron XBB.1.16
    1
    1. scibot 06 Oct 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113193

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    sciencedirect.com/science/article/pii/S2211124723012056
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinome reprogramming is a targetable vulnerability in ESR1 fusion-driven breast cancer
    1
    1. scibot 06 Oct 2023
      RRID:AB_627678

      DOI: 10.1158/0008-5472.CAN-22-3484

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543968/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune Evasion, Infectivity, and Fusogenicity of SARS-CoV-2 Omicron BA.2.86 and FLip Variants
    1
    1. scibot 06 Oct 2023
      RRID:AB_627678

      DOI: 10.1101/2023.09.11.557206

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    ncbi.nlm.nih.gov/pmc/articles/PMC10515800/
  32. Sep 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ESRRB inhibits the TGF-β signaling pathway to drive cell proliferation in cervical cancer
    1
    1. scibot 20 Sep 2023
      RRID:AB_627678

      DOI: 10.1158/0008-5472.CAN-23-0067

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    ncbi.nlm.nih.gov/pmc/articles/PMC10502452/
  34. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
    1. scibot 19 Sep 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  35. Aug 2023
  36. www.sciencedirect.com www.sciencedirect.com
    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
    1
    1. scibot 27 Aug 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.113045

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    sciencedirect.com/science/article/pii/S2211124723010562
  37. www.embopress.org www.embopress.org
    Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
    1
    1. scibot 23 Aug 2023
      RRID:AB_627678

      DOI: 10.15252/emmm.202217367

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    embopress.org/doi/10.15252/emmm.202217367
  38. Jul 2023
  39. www.sciencedirect.com www.sciencedirect.com
    A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development
    1
    1. scibot 27 Jul 2023
      RRID:AB_627678

      DOI: 10.1016/j.chom.2023.06.016

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    sciencedirect.com/science/article/abs/pii/S1931312823002676
  40. www.sciencedirect.com www.sciencedirect.com
    Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.ccell.2023.06.011

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    sciencedirect.com/science/article/pii/S1535610823002362
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
    1
    1. scibot 19 Jul 2023
      RRID:AB_627678

      DOI: 10.1158/0008-5472.CAN-21-4309

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    ncbi.nlm.nih.gov/pmc/articles/PMC9938728/
  42. 52.53.155.43 52.53.155.43
    Conditional lethality profiling reveals anticancer mechanisms of action and drug-nutrient interactions
    1
    1. scibot 19 Jul 2023
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      DOI: 10.1101/2023.06.04.543621

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    52.53.155.43/402e9ae446be9d7677d004a8f8e22b2d6ac49df1/2023.06.04.543621v1.full-html.html
  43. 52.53.155.43 52.53.155.43
    can-23-0067-html.html
    1
    1. scibot 08 Jul 2023
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      DOI: 10.1158/0008-5472.can-23-0067

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    52.53.155.43/1af2a0d742419295c56fc417c605df7b31cfe676/can-23-0067-html.html
  44. www.sciencedirect.com www.sciencedirect.com
    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.005

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    sciencedirect.com/science/article/pii/S0092867423006451
  45. www.embopress.org www.embopress.org
    Homotypic SCOTIN assemblies form ER-endosome membrane contacts and regulate endosome dynamics
    1
    1. scibot 05 Jul 2023
      RRID:AB_627678

      DOI: 10.15252/embr.202256538

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    embopress.org/doi/full/10.15252/embr.202256538
  46. Jun 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models
    1
    1. scibot 30 Jun 2023
      RRID:AB_627678

      DOI: 10.3389/fonc.2023.1200897

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    ncbi.nlm.nih.gov/pmc/articles/PMC10294234/
  48. www.sciencedirect.com www.sciencedirect.com
    KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres
    1
    1. scibot 30 Jun 2023
      RRID:AB_627678

      DOI: 10.1016/j.cell.2023.03.029

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    sciencedirect.com/science/article/abs/pii/S0092867423003264
  49. www.biorxiv.org www.biorxiv.org
    Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
    1
    1. scibot 27 Jun 2023
      RRID:AB_627678

      DOI: 10.1101/2023.06.12.544638

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    biorxiv.org/content/10.1101/2023.06.12.544638v3
  50. www.sciencedirect.com www.sciencedirect.com
    Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression
    1
    1. scibot 16 Jun 2023
      RRID:AB_627678

      DOI: 10.1016/j.celrep.2023.112587

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    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
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    Dihydroartemisinin inhibited stem cell-like properties and enhanced oxaliplatin sensitivity of colorectal cancer via AKT/mTOR signaling
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    Tiam1 coordinates synaptic structural and functional plasticity underpinning the pathophysiology of neuropathic pain
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    Enhanced Evasion of Neutralizing Antibody Response by Omicron XBB.1.5, CH.1.1 and CA.3.1 Variants
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    SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways
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    The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia
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    Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis
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    Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer
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    E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
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    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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    Extraordinary Evasion of Neutralizing Antibody Response by Omicron XBB.1.5, CH.1.1 and CA.3.1 Variants
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    Nicotinamide Nucleotide Transhydrogenase (NNT) is essential for adrenal steroidogenesis: clinical and in vitro lessons
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    A rapid RIG-I signaling relay mediates efficient antiviral response
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    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
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    Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing
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    Angiotensin II regulates mitochondrial mTOR pathway activity dependent on acyl CoA synthetase 4 in adrenocortical cells
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    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
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    Histone deacetylase-2 controls IL-1β production through the regulation of NLRP3 expression and activation in tuberculosis infection
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    High sodium reduced the expression of PTH1R and Klotho by inhibiting 1,25(OH)2D3 synthesis in cultured proximal tubule epithelial cells
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    C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus
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  104. Apr 2022
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    Characterization and functional interrogation of the SARS-CoV-2 RNA interactome
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    The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain
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  107. Mar 2022
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    Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models
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  109. rupress.org rupress.org
    Gap junctions and connexin hemichannels both contribute to the electrical properties of retinal pigment epithelium
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    Differential off-target glucocorticoid activity of progestins used in endocrine therapy
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    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
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    Wnt7a inhibits transformed cell proliferation while promoting migration and invasion in non-small cell lung cancer
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    Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
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    Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection
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  118. Dec 2021
  119. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
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    Anorexia disrupts glutamate-glutamine homeostasis associated with astrocytes in the prefrontal cortex of young female rats
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    Cell adhesion molecule L1 interacts with the chromo shadow domain of heterochromatin protein 1 isoforms α, β, and ɣ via its intracellular domain
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  123. Nov 2021
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    Parp1 promotes sleep, which enhances DNA repair in neurons
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  126. Oct 2021
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    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
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    Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
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    NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson’s Disease
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    Generation of two gene corrected human isogenic iPSC lines (NCATS-CL6104 and NCATS-CL6105) from a patient line (NCATS-CL6103) carrying a homozygous p.R401X mutation in the NGLY1 gene using CRISPR/Cas9
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  131. Sep 2021
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    The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation
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    Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
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    ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer
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  135. Aug 2021
  136. academic.oup.com academic.oup.com
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    Breast tumor kinase (Brk/PTK6) mediates advanced cancer phenotypes via SH2-domain dependent activation of RhoA and aryl hydrocarbon receptor (AhR) signaling
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  143. Jul 2021
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    Changes in cellular Ca2+ and Na+ regulation during the progression towards heart failure in the guinea pig
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      glyceraldehyde 3u2010phosphate dehydrogenase (GAPDH) primary antibody

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    Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics
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    Stratification of clear cell renal cell carcinoma patients to facilitate drug repositioning
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    Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms
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    CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells
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    Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
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  152. Jun 2021
  153. www.cell.com www.cell.com
    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  155. www.sciencedirect.com www.sciencedirect.com
    PRRT2 modulates presynaptic Ca2+ influx by interacting with P/Q-type channels
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    Stress granules inhibit fatty acid oxidation by modulating mitochondrial permeability
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    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
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    ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells
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  159. May 2021
  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer
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    LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway
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    Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs
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    Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
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    Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage
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    Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications
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    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
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  167. Apr 2021
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    Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation
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    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
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    An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
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    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
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    Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms
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  174. Mar 2021
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    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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  176. Feb 2021
  177. www.nature.com www.nature.com
    Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats
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      mouse anti-GAPDH

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  178. www.cell.com www.cell.com
    Cryo-EM Structure of CtBP2 Confirms Tetrameric Architecture
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    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
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  180. Jan 2021
  181. www.jneurosci.org www.jneurosci.org
    Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content
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      DOI: 10.1523/JNEUROSCI.1284-20.2020

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    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
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  183. Dec 2020
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    Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
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    Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
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  186. Oct 2020
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    Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
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    CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
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    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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    Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling
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    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
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    Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells
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    Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori
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    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
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    hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation
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    Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism
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    Conformational Dynamics and Functional Implications of Phosphorylated β-Arrestins
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    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
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    Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP
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    The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family
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    A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis
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    TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation
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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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    Melleolides from Honey Mushroom Inhibit 5-Lipoxygenase via Cys159
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    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission
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    Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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    METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
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    The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse
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    Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation
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    R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
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    Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity
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