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    Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
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  3. Jan 2026
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    Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells
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    Plasma extracellular vesicle sampling from Glioblastoma demonstrates a small RNA signature indicative of disease and identifies lncRNA RPPH1 as a biomarker
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  6. Dec 2025
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    SMURF2 facilitates GAP17 Isoform 1 membrane displacement to promote mutant p53-KRAS oncogenic synergy
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    Wnt10b signaling regulates replication stress–induced chromosomal instability in human cancer
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  12. Jul 2025
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    Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    AQP1- A regulatory factor associated with brown adipose tissue-silencing
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    Cdk6’s functions are critically regulated by its unique C-terminus
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    Microvascular endothelial cells display organ-specific responses to extracellular matrix stiffness
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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  25. Jul 2024
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    Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance
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    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
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    Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells
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  30. May 2024
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    Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo
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    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
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    Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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  39. Dec 2023
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    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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  42. Nov 2023
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  44. Oct 2023
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    Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination
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    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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  48. Aug 2023
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    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
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  53. Apr 2023
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  55. Mar 2023
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    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
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  57. Feb 2023
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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  60. Jan 2023
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    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
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    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
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  63. Dec 2022
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    Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER
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    Systematic analysis of the MAPK signaling network reveals MAP3K-driven control of cell fate
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  67. Jul 2022
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    Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells
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    Sex Differentially Alters Secretion of Brain Extracellular Vesicles During Aging: A Potential Mechanism for Maintaining Brain Homeostasis
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  70. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
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    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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  73. May 2022
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    Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
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  76. Mar 2022
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    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
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  79. Jan 2022
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    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
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    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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  82. Nov 2021
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  84. Aug 2021
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    Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes
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  89. Jul 2021
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    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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    Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease
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    Nuclear translocation promotes proteasomal degradation of human Rad17 protein through the N-terminal destruction boxes
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  93. Jun 2021
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    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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  95. May 2021
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    A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression
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  97. Apr 2021
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    SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis
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    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
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    DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
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  101. Feb 2021
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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  103. Dec 2020
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    UBE1a Suppresses Herpes Simplex Virus-1 Replication
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  105. Sep 2020
  106. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
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    The integrated stress response induces R-loops and hinders replication fork progression
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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    Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP
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    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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  112. Jan 2020
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    Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress
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    Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment
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    An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons
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  117. Nov 2018
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    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
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    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
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    The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair
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    LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia
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  123. Nov 2017
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    A Rapid Induction Mechanism for Lin28a in Trophic Responses
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