70 Matching Annotations
  1. Aug 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
    1
    1. scibot 21 Aug 2024
      RRID:AB_627761

      DOI: 10.1158/2767-9764.CRC-24-0077

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.isci.2024.109912

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    ncbi.nlm.nih.gov/pmc/articles/PMC11225835/
  5. www.cell.com www.cell.com
    Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers
    1
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101648

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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
  6. Jun 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.ydbio.2024.06.003

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    sciencedirect.com/science/article/pii/S0012160624001477
  8. May 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo
    2
    1. scibot 23 May 2024
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      DOI: 10.1007/s00018-024-05266-4

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    2. scibot 23 May 2024
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      DOI: 10.1007/s00018-024-05266-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11106054/
  10. www.sciencedirect.com www.sciencedirect.com
    Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.immuni.2024.04.023

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    sciencedirect.com/science/article/pii/S1074761324002280
  11. Apr 2024
  12. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1111/jnc.16114

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16114
  13. www.sciencedirect.com www.sciencedirect.com
    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
    1
    1. scibot 20 Apr 2024
      RRID:AB_27761

      DOI: 10.1016/j.devcel.2024.03.032

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    sciencedirect.com/science/article/pii/S1534580724002004
  14. link.springer.com link.springer.com
    Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity
    1
    1. scibot 17 Apr 2024
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      DOI: 10.1186/s13024-024-00721-z

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    link.springer.com/article/10.1186/s13024-024-00721-z
  15. Feb 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113845

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    sciencedirect.com/science/article/pii/S2211124724001736
  17. Dec 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
    1
    1. scibot 28 Dec 2023
      RRID:AB_627761

      DOI: 10.1158/0008-5472.CAN-23-1252

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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  19. www.sciencedirect.com www.sciencedirect.com
    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.ccell.2023.11.004

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    sciencedirect.com/science/article/pii/S1535610823003951
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Solubility phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.devcel.2023.10.005

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    sciencedirect.com/science/article/pii/S1534580723005245
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.devcel.2023.09.002

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    sciencedirect.com/science/article/pii/S1534580723004896
  24. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  25. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41467-023-41927-x

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    nature.com/articles/s41467-023-41927-x
  26. Aug 2023
  27. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  28. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1158/0008-5472.can-23-1252

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    52.53.155.43/ea1e2390c2d37ea00d2075acaef6f5d93e41dc17/can-23-1252-html.html
  29. Jul 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
    1
    1. scibot 08 Jul 2023
      AB_627761

      DOI: 10.1158/2643-3230.BCD-22-0029

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    ncbi.nlm.nih.gov/pmc/articles/PMC9816815/
  31. Apr 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
    1
    1. scibot 08 Apr 2023
      AB_627761

      DOI: 10.7554/eLife.86971

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  33. Mar 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
    1
    1. scibot 29 Mar 2023
      RRID:AB_627761

      DOI: 10.1158/2767-9764.CRC-22-0250

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    ncbi.nlm.nih.gov/pmc/articles/PMC10036134/
  35. Feb 2023
  36. www.sciencedirect.com www.sciencedirect.com
    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1016/j.devcel.2023.01.006

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    sciencedirect.com/science/article/pii/S1534580723000370
  37. www.nature.com www.nature.com
    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1038/s41531-023-00465-5

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    nature.com/articles/s41531-023-00465-5
  38. Jan 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
    1
    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112028

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    ncbi.nlm.nih.gov/pmc/articles/PMC10010011/
  40. www.sciencedirect.com www.sciencedirect.com
    Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy
    1
    1. scibot 04 Jan 2023
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      DOI: 10.1016/j.molcel.2022.12.002

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    sciencedirect.com/science/article/pii/S1097276522011376
  41. Dec 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111802

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    sciencedirect.com/science/article/pii/S2211124722016904
  43. Nov 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of the MAPK signaling network reveals MAP3K-driven control of cell fate
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.cels.2022.10.003

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    sciencedirect.com/science/article/pii/S2405471222004306
  45. Jul 2022
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells
    1
    1. scibot 30 Jul 2022
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      DOI: 10.3390/cells11152298

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    ncbi.nlm.nih.gov/pmc/articles/PMC9331440/
  47. link.springer.com link.springer.com
    Sex Differentially Alters Secretion of Brain Extracellular Vesicles During Aging: A Potential Mechanism for Maintaining Brain Homeostasis
    1
    1. scibot 30 Jul 2022
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      DOI: 10.1007/s11064-022-03701-1

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    link.springer.com/article/10.1007/s11064-022-03701-1
  48. Jun 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
    1
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      DOI: 10.1016/j.devcel.2022.06.003

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    sciencedirect.com/science/article/pii/S1534580722004129
  50. www.sciencedirect.com www.sciencedirect.com
    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
    1
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      DOI: 10.1016/j.celrep.2022.110879

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    sciencedirect.com/science/article/pii/S2211124722006544
  51. May 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibitors of dihydroorotate dehydrogenase cooperate with molnupiravir and N4-hydroxycytidine to suppress SARS-CoV-2 replication
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      DOI: 10.1016/j.isci.2022.104293

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    ncbi.nlm.nih.gov/pmc/articles/PMC9035612/
  53. link.springer.com link.springer.com
    Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner
    1
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      DOI: 10.1007/s11064-022-03612-1

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    link.springer.com/article/10.1007/s11064-022-03612-1
  54. Mar 2022
  55. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
    1
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      DOI: 10.7554/eLife.76554

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    ncbi.nlm.nih.gov/pmc/articles/PMC8853661/
  57. Jan 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
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      DOI: 10.1016/j.celrep.2021.110227

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    sciencedirect.com/science/article/pii/S2211124721017319
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
    1
    1. scibot 07 Jan 2022
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      DOI: 10.7554/eLife.69843

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    ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
  60. Nov 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
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    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103264

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    sciencedirect.com/science/article/pii/S2589004221012335
  62. Aug 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes
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      DOI: 10.3389/fimmu.2021.616215

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  67. Jul 2021
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    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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    Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease
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    Nuclear translocation promotes proteasomal degradation of human Rad17 protein through the N-terminal destruction boxes
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  71. Jun 2021
  72. cancerres.aacrjournals.org cancerres.aacrjournals.org
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  73. May 2021
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  75. Apr 2021
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  79. Feb 2021
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  81. Dec 2020
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  83. Sep 2020
  84. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
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    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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    Marine Actinomycetes-Derived Secondary Metabolites Overcome TRAIL-Resistance via the Intrinsic Pathway through Downregulation of Survivin and XIAP
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      HSC70

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    Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells
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  90. Jan 2020
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    Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress
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    Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment
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    An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons
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  95. Nov 2018
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    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
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    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
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    The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair
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    LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia
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  101. Nov 2017
  102. www.sciencedirect.com www.sciencedirect.com
    A Rapid Induction Mechanism for Lin28a in Trophic Responses
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