28 Matching Annotations
  1. Jan 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  5. Nov 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827889/
  7. Oct 2025
  8. www.nature.com www.nature.com
    Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms
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    nature.com/articles/s41416-025-03216-w
  9. Jul 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  11. Apr 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Addiction States Differentially Influence MTH1 Expression and 8-oxodGTPase Activity in Lung Adenocarcinoma
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    sciencedirect.com/science/article/pii/S2213231725001235
  13. Nov 2024
  14. www.sciencedirect.com www.sciencedirect.com
    USP7 deubiquitinates KRAS and promotes non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124724012683
  15. May 2024
  16. www.cell.com www.cell.com
    Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders
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    cell.com/iscience/abstract/S2589-0042(24)01024-1
  17. Jun 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
  19. May 2023
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  21. Apr 2023
  22. link.springer.com link.springer.com
    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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    link.springer.com/article/10.1186/s12935-023-02884-z
  23. Nov 2022
  24. www.sciencedirect.com www.sciencedirect.com
    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124722014942
  25. Feb 2022
  26. www.tandfonline.com www.tandfonline.com
    GTP-binding protein Di-RAS3 diminishes the migration and invasion of non-small cell lung cancer by inhibiting the RAS/extracellular-regulated kinase pathway
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    tandfonline.com/doi/abs/10.1080/21655979.2022.2031671
  27. Sep 2021
  28. www.sciencedirect.com www.sciencedirect.com
    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
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    sciencedirect.com/science/article/pii/S1097276521007140
  29. Jul 2021
  30. mcr.aacrjournals.org mcr.aacrjournals.org
    KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis
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    mcr.aacrjournals.org/content/17/9/1945
  31. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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    sciencedirect.com/science/article/pii/S153561081730555X
  32. Apr 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    sciencedirect.com/science/article/pii/S1535610821001185
  34. www.sciencedirect.com www.sciencedirect.com
    Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
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    sciencedirect.com/science/article/pii/S0092867421003627
  35. Nov 2020
  36. www.sciencedirect.com www.sciencedirect.com
    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S2666379120301737
  37. Sep 2020
  38. www.sciencedirect.com www.sciencedirect.com
    WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion
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    sciencedirect.com/science/article/pii/S1534580720300563
  39. www.sciencedirect.com www.sciencedirect.com
    Defining and Targeting Adaptations to Oncogenic KRASG12C Inhibition Using Quantitative Temporal Proteomics
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    sciencedirect.com/science/article/pii/S2211124720303284
  40. Jan 2020
  41. www.sciencedirect.com www.sciencedirect.com
    EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis
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    sciencedirect.com/science/article/pii/S153458071930485X
  42. Nov 2018
  43. www.sciencedirect.com www.sciencedirect.com
    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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    sciencedirect.com/science/article/pii/S0092867418303088
  44. www.sciencedirect.com www.sciencedirect.com
    KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS
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    sciencedirect.com/science/article/pii/S0092867417315003
  45. Nov 2017
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  47. www.sciencedirect.com www.sciencedirect.com
    RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma
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    sciencedirect.com/science/article/pii/S1535610817301575
  48. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    sciencedirect.com/science/article/pii/S2405471216304082
  49. www.sciencedirect.com www.sciencedirect.com
    Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules
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    sciencedirect.com/science/article/pii/S0092867416316075