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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00246-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00240-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574021/
  4. Sep 2024
  5. www.sciencedirect.com www.sciencedirect.com
    The Role of MFN2 in Regulating Endothelial Cell Senescence: Implications for Vascular Aging
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    sciencedirect.com/science/article/pii/S2589004224020340
  6. Aug 2024
  7. www.sciencedirect.com www.sciencedirect.com
    On the role of p53 in the cellular response to aneuploidy
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    sciencedirect.com/science/article/pii/S2211124721002060
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    Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice
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    1. scibot 19 Aug 2024
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      DOI: 10.1101/2024.07.30.605784

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    biorxiv.org/content/10.1101/2024.07.30.605784v1
  9. Jul 2024
  10. www.cell.com www.cell.com
    Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance
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    cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
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    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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    Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11214290/
  13. Apr 2024
  14. www.sciencedirect.com www.sciencedirect.com
    TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
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    sciencedirect.com/science/article/pii/S1550413124001232
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    Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
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    1. scibot 23 Apr 2024
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    sciencedirect.com/science/article/pii/S0092867424003970
  16. Feb 2024
  17. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    1. scibot 22 Feb 2024
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  19. Jan 2024
  20. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    1. scibot 10 Jan 2024
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  21. Oct 2023
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    A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells
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    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S1097276523007037
  23. Sep 2023
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    Defective uterine spiral artery remodelling and placental senescence in a pregnant rat model of polycystic ovary syndrome
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    sciencedirect.com/science/article/pii/S0002944023003152
  25. Aug 2023
  26. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S2211124723009476
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
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      DOI: 10.3390/ijms241411821

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  29. Jul 2023
  30. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Patterns of senescence and apoptosis during development of branchial arches, epibranchial placodes, and pharyngeal pouches
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    1. scibot 05 Jul 2023
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      DOI: 10.1002/dvdy.637

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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.637
  31. Jun 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
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    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.isci.2023.107028

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    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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    sciencedirect.com/science/article/pii/S0092867423005329
  34. May 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
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      DOI: 10.1016/j.celrep.2023.112520

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    sciencedirect.com/science/article/pii/S2211124723005314
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10173299/
  37. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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    sciencedirect.com/science/article/pii/S2211124723004904
  38. Feb 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
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      DOI: 10.1158/2159-8290.CD-22-0528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
  40. Nov 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Biosensor Cell-Fit-HD4D for correlation of single-cell fate and microscale energy deposition in complex ion beams
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    sciencedirect.com/science/article/pii/S2666166722006785
  42. Sep 2022
  43. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
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    Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors
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    sciencedirect.com/science/article/pii/S2211124722012335
  45. Aug 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Increasing cell size remodels the proteome and promotes senescence
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    sciencedirect.com/science/article/pii/S1097276522007134
  47. Jun 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  49. Apr 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Functional elements of the cis-regulatory lincRNA-p21
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    sciencedirect.com/science/article/pii/S2211124722004454
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
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    sciencedirect.com/science/article/pii/S153458072200079X
  53. link.springer.com link.springer.com
    Partial p53 reactivation is sufficient to induce cancer regression
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      DOI: 10.1186/s13046-022-02269-6

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    link.springer.com/article/10.1186/s13046-022-02269-6
  54. Feb 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Biosensor for deconvolution of individual cell fate in response to ion beam irradiation
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      DOI: 10.1016/j.crmeth.2022.100169

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    sciencedirect.com/science/article/pii/S2667237522000212
  56. Nov 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing
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      DOI: 10.7554/eLife.70153

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    ncbi.nlm.nih.gov/pmc/articles/PMC8592571/
  58. www.sciencedirect.com www.sciencedirect.com
    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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      DOI: 10.1016/j.isci.2021.103327

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    sciencedirect.com/science/article/pii/S2589004221012967
  59. Aug 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.stem.2017.09.004

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