66 Matching Annotations
  1. Feb 2024
  2. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    1. scibot 27 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  3. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101434

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    sciencedirect.com/science/article/pii/S2666379124000570
  4. Jan 2024
  5. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    1. scibot 10 Jan 2024
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      DOI: 10.1158/2767-9764.CRC-23-0308

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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  6. Oct 2023
  7. www.sciencedirect.com www.sciencedirect.com
    A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells
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    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.006

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    sciencedirect.com/science/article/pii/S1097276523007037
  8. Sep 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Defective uterine spiral artery remodelling and placental senescence in a pregnant rat model of polycystic ovary syndrome
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    1. scibot 08 Sep 2023
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    sciencedirect.com/science/article/pii/S0002944023003152
  10. Aug 2023
  11. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    2. scibot 16 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112984

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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
  12. www.sciencedirect.com www.sciencedirect.com
    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
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    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112936

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    sciencedirect.com/science/article/pii/S2211124723009476
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    1. scibot 01 Aug 2023
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      DOI: 10.3390/ijms241411821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  14. Jul 2023
  15. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Patterns of senescence and apoptosis during development of branchial arches, epibranchial placodes, and pharyngeal pouches
    1
    1. scibot 05 Jul 2023
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      DOI: 10.1002/dvdy.637

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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.637
  16. Jun 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.isci.2023.107028

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    ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
  18. www.sciencedirect.com www.sciencedirect.com
    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
    1
    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.013

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    sciencedirect.com/science/article/pii/S0092867423005329
  19. May 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
    1
    1. scibot 18 May 2023
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      DOI: 10.1016/j.celrep.2023.112520

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    sciencedirect.com/science/article/pii/S2211124723005314
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
    1
    1. scibot 16 May 2023
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      DOI: 10.1016/j.omtn.2023.04.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC10173299/
  22. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.celrep.2023.112479

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    sciencedirect.com/science/article/pii/S2211124723004904
  23. Feb 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
    1
    1. scibot 10 Feb 2023
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      DOI: 10.1158/2159-8290.CD-22-0528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
  25. Nov 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Biosensor Cell-Fit-HD4D for correlation of single-cell fate and microscale energy deposition in complex ion beams
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.xpro.2022.101798

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    sciencedirect.com/science/article/pii/S2666166722006785
  27. Sep 2022
  28. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
    1
    1. scibot 27 Sep 2022
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      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  29. www.sciencedirect.com www.sciencedirect.com
    Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111396

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    sciencedirect.com/science/article/pii/S2211124722012335
  30. Aug 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Increasing cell size remodels the proteome and promotes senescence
    1
    1. scibot 22 Aug 2022
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      DOI: 10.1016/j.molcel.2022.07.017

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    sciencedirect.com/science/article/pii/S1097276522007134
  32. Jun 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
    1
    1. scibot 25 Jun 2022
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      DOI: 10.1016/j.isci.2022.104518

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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  34. Apr 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Functional elements of the cis-regulatory lincRNA-p21
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    1. scibot 20 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110687

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    sciencedirect.com/science/article/pii/S2211124722004454
  36. Mar 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
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    1. scibot 04 Mar 2022
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      DOI: 10.1016/j.devcel.2022.02.013

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    sciencedirect.com/science/article/pii/S153458072200079X
  38. link.springer.com link.springer.com
    Partial p53 reactivation is sufficient to induce cancer regression
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    1. scibot 03 Mar 2022
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      DOI: 10.1186/s13046-022-02269-6

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    link.springer.com/article/10.1186/s13046-022-02269-6
  39. Feb 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Biosensor for deconvolution of individual cell fate in response to ion beam irradiation
    1
    1. scibot 18 Feb 2022
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      DOI: 10.1016/j.crmeth.2022.100169

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    sciencedirect.com/science/article/pii/S2667237522000212
  41. Nov 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing
    1
    1. scibot 19 Nov 2021
      RRID:AB_628073

      DOI: 10.7554/eLife.70153

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    ncbi.nlm.nih.gov/pmc/articles/PMC8592571/
  43. www.sciencedirect.com www.sciencedirect.com
    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1016/j.isci.2021.103327

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    sciencedirect.com/science/article/pii/S2589004221012967
  44. Aug 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
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    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109568

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    sciencedirect.com/science/article/pii/S2211124721010020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
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      DOI: 10.1016/j.stem.2017.09.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC5658514/
  47. www.ebiomedicine.com www.ebiomedicine.com
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      DOI: 10.1016/j.ebiom.2016.11.021

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    ebiomedicine.com/article/S2352-3964(16)30525-4/abstract
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.12.071

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    ncbi.nlm.nih.gov/pmc/articles/PMC6334229/
  49. Jul 2021
  50. www.nature.com www.nature.com
    α-Ketoglutarate links p53 to cell fate during tumour suppression
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    1. scibot 30 Jul 2021
      p21

      DOI: 10.1038/s41586-019-1577-5

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    nature.com/articles/s41586-019-1577-5
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.09.060

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    ncbi.nlm.nih.gov/pmc/articles/PMC6205844/
  52. www.sciencedirect.com www.sciencedirect.com
    Early Molecular Stratification of High-risk Primary Biliary Cholangitis
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      Santa Cruz Biotechnology #CatSc-6246; RRID:AB_628073

      DOI: 10.1016/j.ebiom.2016.11.021

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    sciencedirect.com/science/article/pii/S2352396416305254
  53. www.sciencedirect.com www.sciencedirect.com
    Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
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      DOI: 10.1016/j.celrep.2021.109337

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    sciencedirect.com/science/article/pii/S2211124721007130
  54. Jun 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology
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      DOI: 10.1016/j.celrep.2021.109228

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    sciencedirect.com/science/article/pii/S2211124721005799
  56. www.sciencedirect.com www.sciencedirect.com
    Bacterial genotoxins induce T cell senescence
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    1. scibot 09 Jun 2021
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      DOI: 10.1016/j.celrep.2021.109220

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    sciencedirect.com/science/article/pii/S2211124721005714
  57. www.sciencedirect.com www.sciencedirect.com
    ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells
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      DOI: 10.1016/j.exphem.2021.05.006

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    sciencedirect.com/science/article/pii/S0301472X21001995
  58. May 2021
  59. mcr.aacrjournals.org mcr.aacrjournals.org
    Metabolic regulator IAPP (Amylin) is required for BRAF and RAS oncogene-induced senescence
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      DOI: 10.1158/1541-7786.MCR-20-0879

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    mcr.aacrjournals.org/content/19/5/874
  60. www.sciencedirect.com www.sciencedirect.com
    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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      DOI: 10.1016/j.devcel.2020.07.005

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  61. Mar 2021
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    PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
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  64. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
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  71. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration
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  74. Jan 2020
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    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
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    Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
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  81. Nov 2018
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    The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression
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    Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models
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  89. Nov 2017
  90. www.nature.com www.nature.com
    Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism
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    Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System
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