34 Matching Annotations
  1. Jul 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Identification and validation of novel small molecule inhibitors targeting FoxM1-DNA binding domain with anti-cancer potential
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    sciencedirect.com/science/article/pii/S0167488926000923
  3. Apr 2026
  4. aacrjournals.org aacrjournals.org
    Extrachromosomal DNA-Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers
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    aacrjournals.org/cancerdiscovery/article/15/10/2054/765955/Extrachromosomal-DNA-Driven-Oncogene-Dosage
  5. Feb 2026
  6. www.sciencedirect.com www.sciencedirect.com
    NAD+ sensing by PARP7 regulates the C/EBPβ-dependent transcription program during adipogenesis
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    sciencedirect.com/science/article/pii/S2211124726000070
  7. Sep 2025
  8. pubs.acs.org pubs.acs.org
    Multiomics Insights into the Mechanism and Enhanced Efficacy of Tumor Treating Fields (TTFields) Therapy in Glioblastoma
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    pubs.acs.org/doi/10.1021/acs.jproteome.5c00424
  9. May 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ADP-ribosylation of NuMA promotes DNA single-strand break repair and transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12187637/
  11. Apr 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Unveiling transcriptional mechanisms of B7-H3 in breast cancer stem cells through proteomic approaches
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    sciencedirect.com/science/article/pii/S2589004225004791
  13. Feb 2025
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    Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors
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    sciencedirect.com/science/article/pii/S109727652500098X
  15. aacrjournals.org aacrjournals.org
    Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma
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    aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
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    Membrane-tethered SCOTIN condensates elicit an endoplasmic reticulum stress response by sequestering luminal BiP
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    sciencedirect.com/science/article/pii/S2211124725000683
  17. aacrjournals.org aacrjournals.org
    PARP7 Inhibitors and AHR Agonists Act Synergistically Across a Wide-Range of Cancer Models
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    aacrjournals.org/mct/article/24/1/56/750662/PARP7-Inhibitors-and-AHR-Agonists-Act
  18. Jan 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
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    sciencedirect.com/science/article/pii/S2451945624005166
  20. Jul 2024
  21. www.cell.com www.cell.com
    PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00851-9
  22. May 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
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    sciencedirect.com/science/article/pii/S2211124724005333
  24. Apr 2024
  25. link.springer.com link.springer.com
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    link.springer.com/article/10.1038/s41594-024-01294-7
  26. Feb 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    sciencedirect.com/science/article/pii/S2211124724001736
  28. www.biorxiv.org www.biorxiv.org
    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    biorxiv.org/content/10.1101/2023.12.20.572718v1
  29. www.sciencedirect.com www.sciencedirect.com
    PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
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    sciencedirect.com/science/article/pii/S0092867424000527
  30. Jun 2023
  31. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  32. 52.53.155.43 52.53.155.43
    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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    52.53.155.43/333ed306ab43198840b04e278f040205d2c57b40/2023.04.17.537133v1.full-html.html
  33. Apr 2023
  34. www.sciencedirect.com www.sciencedirect.com
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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    sciencedirect.com/science/article/pii/S2211124723003832
  35. Mar 2023
  36. www.sciencedirect.com www.sciencedirect.com
    The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124723002991
  37. Oct 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
  39. Mar 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
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    sciencedirect.com/science/article/pii/S1097276522000855
  41. Dec 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8652299/
  43. Aug 2021
  44. www.sciencedirect.com www.sciencedirect.com
    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    sciencedirect.com/science/article/pii/S2211124718316838
  45. Jun 2021
  46. www.sciencedirect.com www.sciencedirect.com
    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
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    sciencedirect.com/science/article/pii/S109727652100366X
  47. Apr 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor
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    sciencedirect.com/science/article/pii/S0304383521000926
  49. Feb 2021
  50. www.sciencedirect.com www.sciencedirect.com
    CARM1 regulates replication fork speed and stress response by stimulating PARP1
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    sciencedirect.com/science/article/pii/S1097276520309023
  51. Nov 2020
  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Apoptosis, the only cell death pathway that can be measured in human diploid dermal fibroblasts following lethal UVB irradiation
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    pubmed.ncbi.nlm.nih.gov/33144600/
  53. Sep 2020
  54. www.sciencedirect.com www.sciencedirect.com
    Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion
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    sciencedirect.com/science/article/pii/S2211124719316948
  55. Jan 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
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    sciencedirect.com/science/article/pii/S2211124719306874
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1097276519301030
  58. Nov 2018
  59. www.sciencedirect.com www.sciencedirect.com
    Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
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    sciencedirect.com/science/article/pii/S1074761318300931
  60. www.sciencedirect.com www.sciencedirect.com
    ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition
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    sciencedirect.com/science/article/pii/S245194561730435X