180 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    2025.07.29.667421v1.full-html.html
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    52.53.155.43/b596bd38105568fb5cf99ba7e532b5190556003c/2025.07.29.667421v1.full-html.html
  3. www.biorxiv.org www.biorxiv.org
    Distinct 2-phenyl-imidazo[1, 2α] pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor
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    biorxiv.org/content/10.1101/2025.07.28.666967v1
  4. Jul 2025
  5. www.sciencedirect.com www.sciencedirect.com
    Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling
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    sciencedirect.com/science/article/pii/S2211124725008617
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    Topoisomerase IIIα controls alternative lengthening of telomeres
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    sciencedirect.com/science/article/pii/S221112472500837X
  7. journals.biologists.com journals.biologists.com
    CDX2 inducible microRNAs sustain colon cancer by targeting multiple DNA damage response pathway factors
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    journals.biologists.com/jcs/article/134/15/jcs258601/271222/CDX2-inducible-microRNAs-sustain-colon-cancer-by
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    ERRα and HIF-1α Cooperate to Enhance Breast Cancer Aggressiveness and Chemoresistance Under Hypoxic Conditions
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    mdpi.com/2072-6694/17/14/2382
  9. 52.53.155.43 52.53.155.43
    Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15
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    52.53.155.43/afb5e6b037ad2f349bd7a3112c88e9d2144c43dd/2023.03.16.533020v1.full-html.html
  10. www.nature.com www.nature.com
    Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases
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    nature.com/articles/s41419-025-07812-9
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    Cloche/Npas4l is a pro-regenerative platelet factor during zebrafish heart regeneration
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    sciencedirect.com/science/article/pii/S1534580725003703
  12. Jun 2025
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    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    sciencedirect.com/science/article/pii/S1097276525005040
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    The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells
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    sciencedirect.com/science/article/pii/S1097276525005027
  15. May 2025
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    Pituitary folliculo-stellate cells modulate tumor vasculature and extracellular matrix composition in experimental lactosomatotropinomas.
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    sciencedirect.com/science/article/pii/S0006291X2500590X
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adult Neurogenesis in the Subventricular Zone of Patients with Huntington's and Parkinson's Diseases and following Long‐Term Treatment with Deep Brain Stimulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010058/
  18. Mar 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Protocol for single-cell analysis of DNA double-strand break production and repair in cell-cycle phases by automated high-content microscopy
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    sciencedirect.com/science/article/pii/S2666166725000681
  20. Feb 2025
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    Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors
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    sciencedirect.com/science/article/pii/S109727652500098X
  22. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225002809-main-html.html
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  23. Jan 2025
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    A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance
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    sciencedirect.com/science/article/pii/S1534580725000012
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705766/
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    Intestinal Akkermansia muciniphila complements the efficacy of PD1 therapy in MAFLD-related hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2666379124006712
  27. Dec 2024
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microphthalmia and Disrupted Retinal Development Due to a LacZ Knock-in/Knock-Out Allele at the Vsx2 Locus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11603386/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532483/
  30. www.sciencedirect.com www.sciencedirect.com
    Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 activation at stalled forks by RNAPII and DDX39A
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    sciencedirect.com/science/article/pii/S1097276524009894
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    DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance
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    sciencedirect.com/science/article/pii/S1097276524009547
  32. Nov 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
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    sciencedirect.com/science/article/pii/S0092867424011887
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    E2F3a Activates Gadd45b Gene Expression Through PPARα-Mediated Transcriptional Regulation in Hepatic Cells
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    sciencedirect.com/science/article/pii/S1016847824001730
  35. Oct 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
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    sciencedirect.com/science/article/pii/S1097276524007767
  37. Sep 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388196/
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    sciencedirect.com/science/article/pii/S1534580724004921
  40. Aug 2024
  41. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
  42. Jul 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Blending and separating dynamics of RNA-binding proteins develop architectural splicing networks spreading throughout the nucleus
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    sciencedirect.com/science/article/pii/S1097276524005446
  44. Jun 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microphthalmia and disrupted retinal development due to a LacZ knock-in/knock-out allele at the Vsx2 locus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185793/
  46. May 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
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    sciencedirect.com/science/article/pii/S2211124724005333
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    Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization
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    sciencedirect.com/science/article/pii/S1534580724002375
  49. Apr 2024
  50. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
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    ncbi.nlm.nih.gov/pmc/articles/PMC11017726/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10999478/
  53. Mar 2024
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  55. Feb 2024
  56. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
  57. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    sciencedirect.com/science/article/pii/S2211124724001062
  58. Dec 2023
  59. www.sciencedirect.com www.sciencedirect.com
    Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
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    sciencedirect.com/science/article/pii/S0092867423012229
  60. www.sciencedirect.com www.sciencedirect.com
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    sciencedirect.com/science/article/pii/S2211124723014249
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    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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    sciencedirect.com/science/article/pii/S2211124723015097
  62. Nov 2023
  63. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
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    sciencedirect.com/science/article/pii/S2211124723006708
  64. Oct 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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    sciencedirect.com/science/article/pii/S221112472301210X
  66. 52.53.155.43 52.53.155.43
    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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    52.53.155.43/d563fd7ff9ccb7e893aacc6907b2423987643d5e/bqad152-html.html
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    The structural mechanism of dimeric DONSON in replicative helicase activation
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  68. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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  69. Sep 2023
  70. academic.oup.com academic.oup.com
    bvad117-html.html
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    academic.oup.com/jes/article/7/10/bvad117/7274808
  71. Aug 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425727/
  73. 52.53.155.43 52.53.155.43
    ioad095-html.html
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    Small molecule targeting of transcription-replication conflict for selective chemotherapy
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    sciencedirect.com/science/article/pii/S2451945623002210
  75. Jul 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL
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    sciencedirect.com/science/article/pii/S2211124723008987
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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    sciencedirect.com/science/article/pii/S1097276523004720
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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    sciencedirect.com/science/article/pii/S1535610823002179
  79. Jun 2023
  80. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    sciencedirect.com/science/article/pii/S2211124723006794
  81. www.embopress.org www.embopress.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
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    embopress.org/doi/full/10.15252/embr.202256399
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  83. Apr 2023
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    ncbi.nlm.nih.gov/pmc/articles/PMC10104471/
  85. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    science.org/doi/10.1126/sciadv.ade7997
  86. Feb 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
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    ncbi.nlm.nih.gov/pmc/articles/PMC9943068/
  88. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
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    mdpi.com/2073-4409/12/4/555
  89. Dec 2022
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC9781674/
  91. www.sciencedirect.com www.sciencedirect.com
    Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development
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    sciencedirect.com/science/article/pii/S1074761322005933
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9718532/
  93. www.sciencedirect.com www.sciencedirect.com
    POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
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    sciencedirect.com/science/article/pii/S109727652201070X
  94. Nov 2022
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9637995/
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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    sciencedirect.com/science/article/pii/S2211124722014292
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    The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state
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    sciencedirect.com/science/article/pii/S2211124722014395
  98. Sep 2022
  99. www.sciencedirect.com www.sciencedirect.com
    Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
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    sciencedirect.com/science/article/pii/S2211124722011573
  100. Jul 2022
  101. link.springer.com link.springer.com
    Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells
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    link.springer.com/article/10.1007/s11010-022-04504-2
  102. May 2022
  103. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
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    sciencedirect.com/science/article/pii/S2211124722006295
  104. Apr 2022
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic instability from a single S phase after whole-genome duplication
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    ncbi.nlm.nih.gov/pmc/articles/PMC8986533/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cells differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9118116/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8959598/
  108. Mar 2022
  109. www.embopress.org www.embopress.org
    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
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    embopress.org/doi/abs/10.15252/embj.2021110145
  110. www.sciencedirect.com www.sciencedirect.com
    Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression
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    sciencedirect.com/science/article/pii/S155041312200050X
  111. Feb 2022
  112. www.sciencedirect.com www.sciencedirect.com
    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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    sciencedirect.com/science/article/pii/S1097276522000041
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    Gfap transgenic medaka as a novel reporter line for neural stem cells
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    sciencedirect.com/science/article/pii/S0378111922000324
  114. Dec 2021
  115. www.sciencedirect.com www.sciencedirect.com
    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    sciencedirect.com/science/article/pii/S2589004221014747
  116. Nov 2021
  117. www.sciencedirect.com www.sciencedirect.com
    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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    sciencedirect.com/science/article/pii/S1934590921004161
  118. www.sciencedirect.com www.sciencedirect.com
    The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states
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    sciencedirect.com/science/article/pii/S2211124721014170
  119. Oct 2021
  120. www.sciencedirect.com www.sciencedirect.com
    RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair
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    academic.oup.com/endo/article/159/1/297/4210434
  223. europepmc.org europepmc.org
    Life-Long Neurogenic Activity of Individual Neural Stem Cells and Continuous Growth Establish an Outside-In Architecture in the Teleost Pallium
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    europepmc.org/articles/PMC5678050/
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    europepmc.org/articles/PMC5644667/
  225. Nov 2017
  226. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
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    sciencedirect.com/science/article/pii/S1535610817304063
  227. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GSK‐3β Inhibition Suppresses Instability‐induced Osteolysis by a Dual Action on Osteoblast and Osteoclast Differentiation
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26111/full
  228. www.sciencedirect.com www.sciencedirect.com
    Unprotected Replication Forks Are Converted into Mitotic Sister Chromatid Bridges
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    sciencedirect.com/science/article/pii/S1097276517302320