157 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
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    1. scibot 16 Nov 2024
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      DOI: 10.1016/j.cell.2024.10.012

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    sciencedirect.com/science/article/pii/S0092867424011887
  3. Nov 2024
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    E2F3a Activates Gadd45b Gene Expression Through PPARα-Mediated Transcriptional Regulation in Hepatic Cells
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      DOI: 10.1016/j.mocell.2024.100148

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    sciencedirect.com/science/article/pii/S1016847824001730
  5. Oct 2024
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    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
    1
    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S1097276524007767
  7. Sep 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
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    1. scibot 26 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388196/
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    1. scibot 04 Sep 2024
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    sciencedirect.com/science/article/pii/S1534580724004921
  10. Aug 2024
  11. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
    1
    1. scibot 13 Aug 2024
      Santa Cruz Cat# sc-56

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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
  12. Jul 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Blending and separating dynamics of RNA-binding proteins develop architectural splicing networks spreading throughout the nucleus
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    1. scibot 25 Jul 2024
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    sciencedirect.com/science/article/pii/S1097276524005446
  14. Jun 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microphthalmia and disrupted retinal development due to a LacZ knock-in/knock-out allele at the Vsx2 locus
    1
    1. scibot 27 Jun 2024
      AB_628110

      DOI: 10.1101/2024.06.08.597937

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185793/
  16. May 2024
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    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
    1
    1. scibot 16 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005333
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    Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization
    1
    1. scibot 03 May 2024
      AB_6281

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    sciencedirect.com/science/article/pii/S1534580724002375
  19. Apr 2024
  20. 52.53.155.43 52.53.155.43
    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
    1
    1. scibot 18 Apr 2024
      Santa CruzCat# sc-56

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    52.53.155.43/96a93e3423f1799636791061d7a89146b9cf3fe1/andronikou-et-al-2024-parg-deficient-tumor-cells-have-an-increased-dependence-on-exo1-fen1-mediated-dna-repair (1)-html.html
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species
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    1. scibot 18 Apr 2024
      RRID:AB_628110

      DOI: 10.4081/ejh.2024.3977

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    ncbi.nlm.nih.gov/pmc/articles/PMC11017726/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
    1
    1. scibot 10 Apr 2024
      RRID:AB_628110

      DOI: 10.1016/j.isci.2024.109456

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    ncbi.nlm.nih.gov/pmc/articles/PMC10999478/
  23. Mar 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1038/s41467-024-45947-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  25. Feb 2024
  26. 52.53.155.43 52.53.155.43
    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
    1
    1. scibot 22 Feb 2024
      RRID:AB_628110

      DOI: 10.1101/2023.09.27.559698

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    52.53.155.43/9b07aa3872d935df1f2ff4d73fc96f76996bcf22/2023.09.27.559698v1.full-html.html
  27. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    sciencedirect.com/science/article/pii/S2211124724001062
  28. Dec 2023
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    Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.cell.2023.11.006

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    sciencedirect.com/science/article/pii/S0092867423012229
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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      RRID:AB_628110

      DOI: 10.1016/j.celrep.2023.113412

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    sciencedirect.com/science/article/pii/S2211124723014249
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    YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
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      RRID:AB_628110

      DOI: 10.1016/j.celrep.2023.113497

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    sciencedirect.com/science/article/pii/S2211124723015097
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
      RRID:AB_628110

      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
  34. Oct 2023
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    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113198

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    sciencedirect.com/science/article/pii/S221112472301210X
  36. 52.53.155.43 52.53.155.43
    BCAS2 participates in insulin synthesis and secretion via mRNA alternative splicing in mice
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      DOI: 10.1210/endocr/bqad152

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    52.53.155.43/d563fd7ff9ccb7e893aacc6907b2423987643d5e/bqad152-html.html
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    The structural mechanism of dimeric DONSON in replicative helicase activation
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  38. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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      DOI: 10.1038/s41586-023-06657-6

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  39. Sep 2023
  40. academic.oup.com academic.oup.com
    bvad117-html.html
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      DOI: 10.1210/jendso/bvad117

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      RRID:AB_628110

      DOI: 10.1210/jendso/bvad117

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    academic.oup.com/jes/article/7/10/bvad117/7274808
  41. Aug 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk
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      RRID:AB_628110

      DOI: 10.1158/1078-0432.CCR-23-0212

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425727/
  43. 52.53.155.43 52.53.155.43
    ioad095-html.html
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      DOI: 10.1093/biolre/ioad095

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      RRID:AB_628110

      DOI: 10.1093/biolre/ioad095

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    52.53.155.43/6e8a0553b999d4f2f4f17e23268d82d8bf190b47/ioad095-html.html
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    Small molecule targeting of transcription-replication conflict for selective chemotherapy
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      DOI: 10.1016/j.chembiol.2023.07.001

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    sciencedirect.com/science/article/pii/S2451945623002210
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL
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      DOI: 10.1016/j.celrep.2023.112887

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    sciencedirect.com/science/article/pii/S2211124723008987
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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      DOI: 10.1016/j.molcel.2023.06.025

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    sciencedirect.com/science/article/pii/S1097276523004720
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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      DOI: 10.1016/j.ccell.2023.06.007

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    sciencedirect.com/science/article/pii/S1535610823002179
  49. Jun 2023
  50. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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      DOI: 10.1016/j.celrep.2023.112668

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    sciencedirect.com/science/article/pii/S2211124723006794
  51. www.embopress.org www.embopress.org
    PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
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    1. scibot 23 Jun 2023
      RRID:AB_628110

      DOI: 10.15252/embr.202256399

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    embopress.org/doi/full/10.15252/embr.202256399
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  53. Apr 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    1. scibot 20 Apr 2023
      RRID:AB_628110

      DOI: 10.1126/sciadv.ade7997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10104471/
  55. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
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    1. scibot 20 Apr 2023
      RRID:AB_628110

      DOI: 10.1126/sciadv.ade7997

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    science.org/doi/10.1126/sciadv.ade7997
  56. Feb 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
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    1. scibot 23 Feb 2023
      RRID:AB_628110

      DOI: 10.7554/eLife.79013

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    ncbi.nlm.nih.gov/pmc/articles/PMC9943068/
  58. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
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    1. scibot 15 Feb 2023
      RRID:AB_628110

      DOI: 10.3390/cells12040555

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    mdpi.com/2073-4409/12/4/555
  59. Dec 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
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    Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development
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    Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
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    POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
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  64. Nov 2022
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    Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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    The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state
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  68. Sep 2022
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    Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner
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  70. Jul 2022
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    Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells
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  72. May 2022
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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  74. Apr 2022
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cells differentiation
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  78. Mar 2022
  79. www.embopress.org www.embopress.org
    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation
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    Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression
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    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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    Gfap transgenic medaka as a novel reporter line for neural stem cells
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  84. Dec 2021
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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  86. Nov 2021
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    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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    The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states
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  89. Oct 2021
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    RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair
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    Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
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    Role of Heat Shock Factor 1 in Conserving Cholesterol Transportation in Leydig Cell Steroidogenesis via Steroidogenic Acute Regulatory Protein
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    Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
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    USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork
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  95. Sep 2021
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    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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    CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
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    A basal-level activity of ATR links replication fork surveillance and stress response
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  99. Aug 2021
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    Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA
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    Evaluation of the uterine hormonal control of the bat Artibeus lituratus during the different phases of its reproductive cycle
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      DOI: 10.1002/jmor.21098

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  106. Jul 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
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    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
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  111. Jun 2021
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    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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    Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration
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  114. May 2021
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    Histone acetyltransferase EP300 regulates the proliferation and differentiation of neural stem cells during adult neurogenesis and regenerative neurogenesis in the zebrafish optic tectum
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  116. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors
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      DOI: 10.1158/0008-5472.CAN-20-3580

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  117. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The prostate of the bat Artibeus lituratus: Seasonal variations, abiotic regulation, and hormonal control
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      DOI: 10.1002/jmor.21362

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  118. www.sciencedirect.com www.sciencedirect.com
    The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability
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      DOI: 10.1016/j.molcel.2020.11.007

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  119. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
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      DOI: 10.1016/j.molcel.2020.06.028

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  120. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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      DOI: 10.1016/j.molcel.2020.04.031

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  121. www.sciencedirect.com www.sciencedirect.com
    Homology-directed repair protects the replicating genome from metabolic assaults
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  122. www.sciencedirect.com www.sciencedirect.com
    mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways
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      DOI: 10.1016/j.celrep.2021.109069

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  123. Apr 2021
  124. www.sciencedirect.com www.sciencedirect.com
    Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation
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      DOI: 10.1016/j.celrep.2021.108999

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  125. www.sciencedirect.com www.sciencedirect.com
    Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain
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      DOI: 10.1016/j.stem.2021.03.014

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  126. Feb 2021
  127. www.sciencedirect.com www.sciencedirect.com
    CARM1 regulates replication fork speed and stress response by stimulating PARP1
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  128. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Administration of 5‐Bromo‐2´‐Deoxyuridine interferes with neuroblast proliferation and promotes apoptotic cell death in the rat cerebellar neuroepithelium
    1
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      DOI: 10.1002/cne.25005

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    onlinelibrary.wiley.com/doi/10.1002/cne.25005
  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    P2X7 and A2A receptor endogenous activation protects against neuronal death caused by CoCl2‐induced photoreceptor toxicity in the zebrafish retina
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      DOI: 10.1002/cne.24869

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  130. Jan 2021
  131. www.sciencedirect.com www.sciencedirect.com
    DCAF14 promotes stalled fork stability to maintain genome integrity
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      DOI: 10.1016/j.celrep.2020.108669

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  132. www.sciencedirect.com www.sciencedirect.com
    Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination
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    1. scibot 21 Jan 2021
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      DOI: 10.1016/j.molcel.2020.12.025

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  133. www.jneurosci.org www.jneurosci.org
    The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation
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      DOI: 10.1523/JNEUROSCI.0604-20.2020

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  134. Dec 2020
  135. www.sciencedirect.com www.sciencedirect.com
    TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A
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      RRID:AB_628110

      DOI: 10.1016/j.celrep.2020.108543

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  136. www.sciencedirect.com www.sciencedirect.com
    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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      DOI: 10.1016/j.celrep.2020.108546

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  137. Nov 2020
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
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      DOI: 10.7554/eLife.58020

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  139. www.sciencedirect.com www.sciencedirect.com
    Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain
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      DOI: 10.1016/j.cmet.2020.09.011

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  140. www.frontiersin.org www.frontiersin.org
    The Effects of Anesthesia on Adult Hippocampal Neurogenesis
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      DOI: 10.3389/fnins.2020.588356

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    frontiersin.org/articles/10.3389/fnins.2020.588356/full
  141. Sep 2020
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
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      RRID:AB_628110

      DOI: 10.1016/j.ccell.2020.01.001

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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
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      RRID:AB_628110

      DOI: 10.7554/eLife.52091

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  144. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endoplasmic reticulum associated degradation is required for maintaining endoplasmic reticulum homeostasis and viability of mature Schwann cells in adults
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      DOI: 10.1002/glia.23910

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  145. www.sciencedirect.com www.sciencedirect.com
    RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling
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      DOI: 10.1016/j.celrep.2020.108002

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    Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
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      DOI: 10.1016/j.celrep.2020.01.067

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  147. www.sciencedirect.com www.sciencedirect.com
    BRCA1 Mutational Complementation Induces Synthetic Viability
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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      DOI: 10.1158/0008-5472.CAN-18-4075

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  149. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐127‐5p impairs function of granulosa cells via HMGB2 gene in premature ovarian insufficiency
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      DOI: 10.1002/jcp.29725

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  150. www.sciencedirect.com www.sciencedirect.com
    Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development
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      DOI: 10.1016/j.devcel.2020.02.003

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    CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression
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      DOI: 10.1016/j.celrep.2020.107630

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  152. www.sciencedirect.com www.sciencedirect.com
    Acetylation of UHRF1 Regulates Hemi-methylated DNA Binding and Maintenance of Genome-wide DNA Methylation
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      RRID:AB_628110

      DOI: 10.1016/j.celrep.2020.107958

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  153. www.sciencedirect.com www.sciencedirect.com
    Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
    1
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      DOI: 10.1016/j.molcel.2019.11.013

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  154. elifesciences.org elifesciences.org
    p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways
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      DOI: 10.7554/eLife.31723

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  155. Jan 2020
  156. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells
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      DOI: 10.1016/j.cub.2019.09.041

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  157. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
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      DOI: 10.1016/j.chembiol.2019.12.005

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  158. www.sciencedirect.com www.sciencedirect.com
    CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer
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      DOI: 10.1016/j.ccell.2019.11.003

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  159. www.sciencedirect.com www.sciencedirect.com
    Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation
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      DOI: 10.1016/j.devcel.2019.10.019

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    Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators
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      DOI: 10.1016/j.celrep.2019.08.051

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    PCNA Unloading Is Negatively Regulated by BET Proteins
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      DOI: 10.1016/j.celrep.2019.11.114

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  162. www.sciencedirect.com www.sciencedirect.com
    EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2
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      RRID:AB_628110

      DOI: 10.1016/j.molcel.2019.05.026

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    GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis
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  169. Nov 2018
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    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
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    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
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    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
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    The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression
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    Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2
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    mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma
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    Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
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    BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation
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    Paneth Cell Multipotency Induced by Notch Activation following Injury
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    SLFN11 Blocks Stressed Replication Forks Independently of ATR
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    Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
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    Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
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    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
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    Molecular Anatomy of the Developing Human Retina
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    Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity
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  193. europepmc.org europepmc.org
    Life-Long Neurogenic Activity of Individual Neural Stem Cells and Continuous Growth Establish an Outside-In Architecture in the Teleost Pallium
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  195. Nov 2017
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    Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
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  197. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GSK‐3β Inhibition Suppresses Instability‐induced Osteolysis by a Dual Action on Osteoblast and Osteoclast Differentiation
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    Unprotected Replication Forks Are Converted into Mitotic Sister Chromatid Bridges
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