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SLX4IP limits replication stress globally and at ALT telomeres

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s44318-026-00790-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13269807/
Feb 2026
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Local heterochromatin enrichment promotes telomere clustering and PML nuclear body assembly at telomeres

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117004
  
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sciencedirect.com/science/article/pii/S2211124726000823
Oct 2025
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Sp100A isoform promotes localization of the histone chaperone HIRA to PML nuclear bodies

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.jbc.2025.110814
  
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sciencedirect.com/science/article/pii/S0021925825026663
Jul 2025
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Topoisomerase IIIα controls alternative lengthening of telomeres

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1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116066
  
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sciencedirect.com/science/article/pii/S221112472500837X
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TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling

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1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.009
  
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sciencedirect.com/science/article/pii/S109727652500509X
May 2025
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Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115766
  
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1-s2.0-S2589004225008168-main-html.html

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112555
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
Apr 2025
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ARC/ARG3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115525
  
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sciencedirect.com/science/article/pii/S2211124725002967
Jan 2025
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Identification of modulators of the ALT pathway through a native FISH-based optical screen

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115114
  
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sciencedirect.com/science/article/pii/S2211124724014657
Aug 2024
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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.07.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
Apr 2024
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BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.molcel.2024.03.011
  
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sciencedirect.com/science/article/pii/S1097276524002211
Jan 2024
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Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair

1
1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113656
  
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sciencedirect.com/science/article/pii/S2211124723016674
Nov 2023
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Targeted perturbation of signaling-driven condensates

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.molcel.2023.10.023
  
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sciencedirect.com/science/article/pii/S1097276523008602
Aug 2023
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Senescent cells form nuclear foci that contain the 26S proteasome

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1. scibot 04 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112880
  
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sciencedirect.com/science/article/pii/S2211124723008914
May 2023
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Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.xgen.2023.100321
  
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sciencedirect.com/science/article/pii/S2666979X23000897
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ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112495
  
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sciencedirect.com/science/article/pii/S2211124723005065
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Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.celrep.2022.111086
  
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sciencedirect.com/science/article/pii/S2211124722008889
Apr 2023
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DNA-initiated epigenetic cascades driven by C9orf72 hexanucleotide repeat

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1. scibot 27 Apr 2023
  
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  RRID:AB_628162
  
  DOI: 10.1016/j.neuron.2023.01.022
  
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sciencedirect.com/science/article/pii/S0896627323000727
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Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair

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1. scibot 14 Apr 2023
  
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  RRID:AB_628162
  
  DOI: 10.1016/j.molcel.2023.03.021
  
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sciencedirect.com/science/article/pii/S1097276523002113
Nov 2022
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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma

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1. scibot 09 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111623
  
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sciencedirect.com/science/article/pii/S2211124722014942
Oct 2022
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RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA

1
1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.025
  
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sciencedirect.com/science/article/pii/S1097276522009352
Apr 2022
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Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.molcel.2022.03.033
  
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sciencedirect.com/science/article/pii/S1097276522002891
Aug 2021
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.cell.2018.10.057
  
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sciencedirect.com/science/article/pii/S0092867418314569
Jul 2021
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Untitled document

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1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.molcel.2018.10.036
  
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sciencedirect.com/science/article/pii/S1097276518308967
May 2021
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Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

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1. scibot 21 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.028
  
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sciencedirect.com/science/article/pii/S1097276521003579
Sep 2020
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Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107983
  
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sciencedirect.com/science/article/pii/S2211124720309682
Jan 2020
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GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.devcel.2019.11.006
  
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sciencedirect.com/science/article/pii/S1534580719309372
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.06.043
  
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sciencedirect.com/science/article/pii/S1097276519305003
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TSPYL5 Depletion Induces Specific Death of ALT Cells through USP7-Dependent Proteasomal Degradation of POT1

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.05.027
  
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sciencedirect.com/science/article/pii/S1097276519303995
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SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.07.010
  
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  RRID:AB_628162 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519305404
Nov 2018
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Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments

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1. scibot 05 Nov 2018
  
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  RRID:AB_628162 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276518306877