18 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SHP2 regulates VEGFR2 Y1175/ PLCγ signaling to impair tumor endothelial barrier stability
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915272/
  3. Jan 2026
  4. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226001598-main-html.html
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    54.241.53.176/c9c076bed7a8fde5420672e62ca2e6fd745c85b4/1-s2.0-S2589004226001598-main-html.html
  5. Dec 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
  7. Jul 2025
  8. www.cell.com www.cell.com
    TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC
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    cell.com/cell-reports/abstract/S2211-1247(25)00743-0
  9. Feb 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    sciencedirect.com/science/article/pii/S1074761324000360
  11. Jan 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    sciencedirect.com/science/article/pii/S2666379123006031
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    An autonomous activation of interleukin-17 receptor signaling sustains inflammation and promotes disease progression
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    sciencedirect.com/science/article/abs/pii/S1074761323002698
  15. Jun 2023
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters
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    pmc.ncbi.nlm.nih.gov/articles/PMC10244369/
  17. Nov 2022
  18. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
  19. Dec 2021
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8631942/
  21. Nov 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment
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    sciencedirect.com/science/article/pii/S2211124721014534
  23. Apr 2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8024022/
  25. Oct 2020
  26. www.cell.com www.cell.com
    Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
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    cell.com/cell/fulltext/S0092-8674(20)31143-0
  27. Sep 2020
  28. www.jbc.org www.jbc.org
    Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet–induced hepatic steatosis and insulin resistance by elevating IL-18 levels
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    jbc.org/content/295/31/10842.full
  29. Jan 2020
  30. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S2211124719309118
  31. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718319247
  32. www.sciencedirect.com www.sciencedirect.com
    Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis
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    sciencedirect.com/science/article/pii/S2352396419301744