109 Matching Annotations
  1. Apr 2024
  2. www.nature.com www.nature.com
    Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies
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    1. scibot 18 Apr 2024
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      DOI: 10.1038/s41467-024-47569-x

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    nature.com/articles/s41467-024-47569-x
  3. www.sciencedirect.com www.sciencedirect.com
    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.013

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    sciencedirect.com/science/article/pii/S1934590924000948
  4. Mar 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    1. scibot 28 Mar 2024
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      DOI: 10.1016/j.isci.2024.109288

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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease
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    1. scibot 27 Mar 2024
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      DOI: 10.4103/1673-5374.389356

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960274/
  7. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.009

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    2. scibot 15 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.009

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    sciencedirect.com/science/article/pii/S155041312400055X
  8. Feb 2024
  9. www.sciencedirect.com www.sciencedirect.com
    NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113860

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    sciencedirect.com/science/article/pii/S2211124724001888
  10. 52.53.155.43 52.53.155.43
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
    2
    1. scibot 22 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    2. scibot 22 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    52.53.155.43/d532629e4f1cf755a6f5c302a21018f2c97350c4/reisbeck-et-al-2023-the-iron-chelator-and-oxphos-inhibitor-vlx600-induces-mitophagy-and-an-autophagy-dependent-type-of (1)-html.html
  11. journals.physiology.org journals.physiology.org
    The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells
    3
    1. scibot 16 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    2. scibot 16 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    3. scibot 16 Feb 2024
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      DOI: 10.1152/ajpcell.00293.2023

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    journals.physiology.org/doi/10.1152/ajpcell.00293.2023
  12. www.sciencedirect.com www.sciencedirect.com
    The HRI branch of the integrated stress response selectively triggers mitophagy
    2
    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.016

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    2. scibot 14 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.016

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    sciencedirect.com/science/article/pii/S1097276524000522
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss
    1
    1. scibot 01 Feb 2024
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      DOI: 10.12688/f1000research.53230.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10808857/
  14. Jan 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1158/2159-8290.CD-22-0601

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    ncbi.nlm.nih.gov/pmc/articles/PMC10330144/
  16. Nov 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
    1
    1. scibot 30 Nov 2023
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      DOI: 10.1038/s41467-023-43175-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
  18. Oct 2023
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1111/acel.13996

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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  20. Sep 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Examining PI3K-signaling-dependent regulation of lens organelle free zone formation via immunolocalization and immunoblotting in chick embryos
    1
    1. scibot 23 Sep 2023
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      DOI: 10.1016/j.xpro.2023.102569

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509694/
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
    1
    1. scibot 22 Sep 2023
      RRID:AB_628381

      DOI: 10.1111/acel.13954

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    onlinelibrary.wiley.com/doi/10.1111/acel.13954
  23. link.springer.com link.springer.com
    Melatonin Prevents Non-image-Forming Visual System Alterations Induced by Experimental Glaucoma in Rats
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1007/s12035-021-02374-1

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    link.springer.com/article/10.1007/s12035-021-02374-1
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain-derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase A
    1
    1. scibot 13 Sep 2023
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      DOI: 10.1111/jnc.15945

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15945
  25. www.sciencedirect.com www.sciencedirect.com
    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.molcel.2023.08.005

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    sciencedirect.com/science/article/pii/S109727652300641X
  26. Aug 2023
  27. www.biorxiv.org www.biorxiv.org
    KAT8 compound inhibition inhibits PINK1/Parkin-dependent mitophagy and initiates mitochondrial delivery to lysosomes
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1101/2023.08.03.551835

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    biorxiv.org/content/10.1101/2023.08.03.551835v1
  28. Jul 2023
  29. www.sciencedirect.com www.sciencedirect.com
    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112895

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    sciencedirect.com/science/article/pii/S2211124723009063
  30. www.sciencedirect.com www.sciencedirect.com
    A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts
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    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.isci.2023.107159

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    sciencedirect.com/science/article/pii/S2589004223012361
  31. 52.53.155.43 52.53.155.43
    cd-22-0601-html.html
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    1. scibot 01 Jul 2023
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      DOI: 10.1158/2159-8290.cd-22-0601

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    52.53.155.43/290a9e83c2986d3a20253cf2b728f2d5cb830f48/cd-22-0601-html.html
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial iron-responsive pathway regulated by DELE1
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.031

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    sciencedirect.com/science/article/pii/S1097276523004136
  34. www.sciencedirect.com www.sciencedirect.com
    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cmet.2023.05.007

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    sciencedirect.com/science/article/pii/S1550413123001845
  35. www.sciencedirect.com www.sciencedirect.com
    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.018

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    sciencedirect.com/science/article/pii/S109727652300374X
  36. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  37. May 2023
  38. www.sciencedirect.com www.sciencedirect.com
    The ultrastructural function of MLN64 in the late endosome–mitochondria membrane contact sites in placental cells
    1
    1. scibot 31 May 2023
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      DOI: 10.1016/j.yexcr.2023.113668

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    sciencedirect.com/science/article/pii/S001448272300215X
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice
    1
    1. scibot 31 May 2023
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      DOI: 10.3390/cells12101435

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    ncbi.nlm.nih.gov/pmc/articles/PMC10216974/
  40. Apr 2023
  41. www.sciencedirect.com www.sciencedirect.com
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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      DOI: 10.1016/j.celrep.2023.112372

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    sciencedirect.com/science/article/pii/S2211124723003832
  42. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis
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      DOI: 10.1016/j.cmet.2023.01.003

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    sciencedirect.com/science/article/pii/S1550413123000037
  43. www.biorxiv.org www.biorxiv.org
    Optineurin provides a mitophagy contact site for TBK1 activation
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    1. scibot 12 Apr 2023
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      DOI: 10.1101/2023.02.24.529790

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    biorxiv.org/content/10.1101/2023.02.24.529790v1
  44. Mar 2023
  45. www.cell.com www.cell.com
    TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
    1
    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.molcel.2023.02.023

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    cell.com/molecular-cell/abstract/S1097-2765(23)00150-8
  46. Feb 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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    1. scibot 19 Feb 2023
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      DOI: 10.1016/j.isci.2023.106045

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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
  48. www.sciencedirect.com www.sciencedirect.com
    Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.nbd.2023.106031

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    sciencedirect.com/science/article/pii/S0969996123000451
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites
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    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.devcel.2022.12.010

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    sciencedirect.com/science/article/pii/S1534580722008760
  51. Dec 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
    1
    1. scibot 09 Dec 2022
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      DOI: 10.7554/eLife.84279

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    ncbi.nlm.nih.gov/pmc/articles/PMC9725753/
  53. Nov 2022
  54. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
    1
    1. scibot 19 Nov 2022
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      DOI: 10.15252/embj.2022112006

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    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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    Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon
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  57. Aug 2022
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    Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
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    Integrative analysis of mitochondrial metabolic dynamics in reprogramming human fibroblast cells
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    Mitochondrial LETM1 drives ionic and molecular clock rhythms in circadian pacemaker neurons
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
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    Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
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  68. Jan 2022
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    The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis
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    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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    Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons
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  72. Dec 2021
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    SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes
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    TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules
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  76. Aug 2021
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    Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes
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  83. Jul 2021
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    SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance
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    Human Immunodeficiency Virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia
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    Global mapping of Salmonella enterica-host protein-protein interactions during infection
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    Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
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    Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity
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    Super-resolution imaging reveals cytoskeleton-dependent organelle rearrangement within platelets at intermediate stages of maturation
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    High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol
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  92. May 2021
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    TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  96. Apr 2021
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    Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
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  101. Feb 2021
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    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
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    NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation
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  104. Jan 2021
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    Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content
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  106. Dec 2020
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    Melanoma Persister Cells Are Tolerant to BRAF/MEK Inhibitors via ACOX1-Mediated Fatty Acid Oxidation
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  108. Nov 2020
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    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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  110. Oct 2020
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    Phosphorylation of STAT3 by axonal Cdk5 promotes axonal regeneration by modulating mitochondrial activity
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    Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma
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  113. Sep 2020
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    Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
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  116. rupress.org rupress.org
    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
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    Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency
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    Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits
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    Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling
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      DOI: 10.1016/j.devcel.2020.05.014

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    SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation
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    Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease
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      DOI: 10.1093/hmg/ddaa066

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  123. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      mouse anti-TOM20

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  124. Aug 2020
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    Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease
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  126. academic.oup.com academic.oup.com
    Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
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  127. Jan 2020
  128. advances.sciencemag.org advances.sciencemag.org
    Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress
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      DOI: 10.1126/sciadv.aax1978

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    TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
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      DOI: 10.1016/j.celrep.2019.07.036

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    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
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      DOI: 10.1016/j.molcel.2019.06.040

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      DOI: 10.1016/j.molcel.2019.01.002

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    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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      DOI: 10.1016/j.molcel.2018.11.034

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      DOI: 10.1016/j.cmet.2018.12.013

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    Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING
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      RRID:AB_628381

      DOI: 10.1016/j.molcel.2019.02.038

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  136. Nov 2018
  137. www.sciencedirect.com www.sciencedirect.com
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    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
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    sciencedirect.com/science/article/pii/S1550413118303140
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    TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer
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    sciencedirect.com/science/article/pii/S0960982217316809
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    Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway
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  141. Nov 2017
  142. www.sciencedirect.com www.sciencedirect.com
    Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
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      sc-17764

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    Mitochondrial mechanisms of neuronal rescue by F-68, a hydrophilic Pluronic block co-polymer, following acute substrate deprivation
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