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Pharmacologic interrogation of USP28 cellular function in p53 signaling

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.chembiol.2025.08.002
  
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sciencedirect.com/science/article/pii/S2451945625002326
Aug 2025
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Design of a selective peptide inhibitor targeting KDM5C demethylase activity

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1. scibot 28 Aug 2025
  
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  DOI: 10.1016/j.str.2025.08.001
  
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sciencedirect.com/science/article/pii/S096921262500303X
Jan 2025
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Adenylate cyclase 10 promotes brown adipose tissue thermogenesis

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1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111833
  
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sciencedirect.com/science/article/pii/S2589004225000938
Dec 2024
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CAF-1 promotes efficient PrimPol recruitment to nascent DNA for single-stranded DNA gap formation

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1. scibot 13 Dec 2024
  
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  Santa Cruz Biotechnology sc-25336
  
  DOI: 10.1093/nar/gkae1068
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1068/7903364
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers

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1. scibot 11 Dec 2024
  
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  DOI: 10.1158/2159-8290.CD-23-0866
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
Sep 2024
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An adenosinergic positive feedback loop extends pharmacological cardioprotection duration

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1. scibot 27 Sep 2024
  
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  DOI: 10.1111/bph.17331
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17331
Jul 2024
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The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.molcel.2024.06.031
  
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cell.com/molecular-cell/fulltext/S1097-2765(24)00538-0
Feb 2024
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A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients

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1. scibot 24 Feb 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-2005
  
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aacrjournals.org/clincancerres/article/29/24/5047/731678/A-Phase-I-Expansion-Cohort-Study-Evaluating-the
Dec 2023
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ccr-23-2005-html.html

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1. scibot 01 Dec 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-2005
  
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52.53.155.43/8373d350712629607ae5ff64c6434e7646ebbbe9/ccr-23-2005-html.html
Nov 2023
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Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs

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1. scibot 03 Nov 2023
  
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  DOI: 10.1016/j.crmeth.2023.100628
  
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sciencedirect.com/science/article/pii/S2667237523002928
Oct 2023
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Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia

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1. scibot 22 Oct 2023
  
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  RRID:AB_628438
  
  DOI: 10.3390/ijms242015225
  
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mdpi.com/1422-0067/24/20/15225
Sep 2023
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TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

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1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.stem.2023.07.001
  
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sciencedirect.com/science/article/pii/S1934590923002461
Aug 2023
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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer

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1. scibot 04 Aug 2023
  
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  DOI: 10.1158/1535-7163.MCT-23-0110
  
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aacrjournals.org/mct/article/22/8/962/727921/Vincristine-Enhances-the-Efficacy-of-MEK
Jul 2023
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Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy

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1. scibot 29 Jul 2023
  
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  DOI: 10.1158/2767-9764.CRC-23-0111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10373600/
May 2023
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BPS Publications

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1. scibot 18 May 2023
  
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  RRID:AB_628438
  
  DOI: 10.1111/bph.16087
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16087
Mar 2023
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Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

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1. scibot 26 Mar 2023
  
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  DOI: 10.1371/journal.pone.0281063
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10035898/
Jan 2023
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Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111972
  
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sciencedirect.com/science/article/pii/S2211124722018769
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.stem.2022.12.006
  
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sciencedirect.com/science/article/pii/S1934590922004908
Sep 2022
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Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency

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1. scibot 15 Sep 2022
  
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  DOI: 10.1038/s42003-022-03942-4
  
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nature.com/articles/s42003-022-03942-4
Jul 2022
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ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions

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1. scibot 27 Jul 2022
  
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  DOI: 10.3389/fendo.2022.930227
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9299245/
Jul 2021
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SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

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1. scibot 14 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109345
  
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sciencedirect.com/science/article/pii/S221112472100721X
Apr 2021
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Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor

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1. scibot 01 Apr 2021
  
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  DOI: 10.1016/j.canlet.2021.02.018
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S0304383521000926
Mar 2021
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The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks

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1. scibot 08 Mar 2021
  
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  DOI: 10.1016/j.molcel.2020.10.009
  
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sciencedirect.com/science/article/pii/S1097276520306924
Oct 2020
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MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia

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1. scibot 01 Oct 2020
  
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  DOI: 10.1016/j.stem.2020.09.004
  
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sciencedirect.com/science/article/pii/S1934590920304501
Sep 2020
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

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1. scibot 15 Sep 2020
  
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  RRID:AB_628438
  
  DOI: 10.1016/j.stem.2020.04.009
  
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sciencedirect.com/science/article/pii/S193459092030148X
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WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.01.024
  
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sciencedirect.com/science/article/pii/S1534580720300563
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Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells

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1. scibot 03 Sep 2020
  
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  Vinculin
  
  DOI: 10.3390/cancers12061643
  
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  Curator: @Naa003
  
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mdpi.com/2072-6694/12/6/1643
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.04.034
  
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sciencedirect.com/science/article/pii/S2211124719304991
Nov 2017
onlinelibrary.wiley.com onlinelibrary.wiley.com

IFN‐gamma priming of adipose‐derived stromal cells at “physiological” hypoxia

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.26046/full
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BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

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1. scibot 08 Nov 2017
  
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  AB_628438
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1097276517304069