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Feb 2026
www.nature.com www.nature.com

Epigenetic regulation of NDGA and its synergistic inhibition with EZH2 inhibitors in prostate cancer via NRP1

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  DOI: 10.1038/s41401-026-01754-4
  
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nature.com/articles/s41401-026-01754-4
Jan 2026
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Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target

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  DOI: 10.1016/j.xcrm.2025.102578
  
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sciencedirect.com/science/article/pii/S2666379125006512
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spirodelae Herba ethanol extract attenuates neurotoxicity in hippocampal cells and improves scopolamine-induced cognitive impairment in mice

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1. scibot 20 Sep 2025
  
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  DOI: 10.3389/fphar.2025.1638068
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12422933/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway

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1. scibot 07 Sep 2025
  
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  DOI: 10.4103/NRR.NRR-D-23-01953
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12407559/
Aug 2025
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jun 2025
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Triflumizole induces excessive reactive oxygen species, inhibits the GPR30/PI3K/AKT pathway, and triggers apoptosis and autophagy in GC-1 spermatogonia cells

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1. scibot 04 Jun 2025
  
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  DOI: 10.1016/j.pestbp.2025.106486
  
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sciencedirect.com/science/article/pii/S0048357525001993
May 2025
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Sumoylated Etv1 establishes mouse mammary cancer stem cells that support tumorigenesis by non-stem cancer cells

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.005
  
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sciencedirect.com/science/article/pii/S1534580725002072
Mar 2025
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PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth

1
1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.02.024
  
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sciencedirect.com/science/article/pii/S1097276525001868
Feb 2025
dx.doi.org dx.doi.org

The TSH receptor antibody reactome contributes to retro-orbital inflammation

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1. scibot 20 Feb 2025
  
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  DOI: 10.1210/jendso/bvae182
  
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dx.doi.org/10.1210/jendso/bvae182
aacrjournals.org aacrjournals.org

Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1535-7163.MCT-21-0848
  
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aacrjournals.org/mct/article/21/7/1160/705294/Peptide-PDHPS1-Inhibits-Ovarian-Cancer-Growth
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TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/0008-5472.CAN-22-3009
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

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1. scibot 23 Jan 2025
  
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  DOI: 10.7554/eLife.94420
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750134/
Dec 2024
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Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism

2
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.001
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.immuni.2024.11.001
  
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sciencedirect.com/science/article/pii/S1074761324004965
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neuregulin 1 signaling attenuates tumor necrosis factor-α induced female rat luteal cell death

1
1. scibot 09 Oct 2024
  
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  DOI: 10.1210/endocr/bqae129
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11456883/
Sep 2024
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Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114762
  
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sciencedirect.com/science/article/pii/S2211124724011136
Aug 2024
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Contactin -Associated protein1 Regulates Autophagy by Modulating the PI3K/AKT/mTOR Signaling Pathway and ATG4B Levels in Vitro and in Vivo

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1. scibot 25 Aug 2024
  
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  DOI: 10.1007/s12035-024-04425-9
  
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link.springer.com/article/10.1007/s12035-024-04425-9
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Sex-Dimorphic Effects of Glucose Transporter-2 Gene Knockdown on Hypothalamic Primary Astrocyte Phosphoinositide-3-kinase (PI3K)/Protein Kinase B (PKB/Akt)/Mammalian Target of Rapamycin (mTOR) Cascade Protein Expression and Phosphorylation

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.mce.2024.112341
  
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sciencedirect.com/science/article/pii/S0303720724001977
Apr 2024
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Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect

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1. scibot 24 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114132
  
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sciencedirect.com/science/article/pii/S2211124724004601
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Melatonin improves synapse development by PI3K/Akt signaling in a mouse model of autism spectrum disorder

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1. scibot 28 Feb 2024
  
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  DOI: 10.4103/1673-5374.387973
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10883500/
Jun 2023
52.53.155.43 52.53.155.43

Endothelial MRs mediate Western diet-induced lipid disorders and skeletal muscle insulin resistance in females

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1. scibot 15 Jun 2023
  
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  DOI: 10.1210/endocr/bqad091
  
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52.53.155.43/505020cd5ddad21196b5171a72c7e74f4f7d8201/bqad091-html.html
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 01 Jun 2023
  
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  DOI: 10.1111/bph.16080
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
Apr 2023
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CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

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1. scibot 23 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106524
  
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sciencedirect.com/science/article/pii/S2589004223006016
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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112186
  
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sciencedirect.com/science/article/pii/S2211124723001973
Feb 2023
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PIMT regulates Hepatic Gluconeogenesis in Mice

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  DOI: 10.1016/j.isci.2023.106120
  
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sciencedirect.com/science/article/pii/S2589004223001979
Dec 2022
52.53.155.43 52.53.155.43

Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways

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1. scibot 14 Dec 2022
  
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  DOI: 10.3390/ijms231911445
  
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  DOI: 10.3390/ijms231911445
  
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52.53.155.43/eb3e7bd6fec17f8c00ac186e434aef30e82c163b/ijms-23-11445-html.html
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The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity

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  DOI: 10.3390/cimb44120402
  
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mdpi.com/1467-3045/44/12/402
Sep 2022
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The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling

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1. scibot 27 Sep 2022
  
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  DOI: 10.1016/j.jbc.2022.102532
  
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sciencedirect.com/science/article/pii/S0021925822009759
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell

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1. scibot 30 Jul 2022
  
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  DOI: 10.1186/s13048-022-01021-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9316729/
Jun 2022
52.53.155.43 52.53.155.43

mct-21-0848-html.html

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  DOI: 10.1158/1535-7163.mct-21-0848
  
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52.53.155.43/12e7b7b771463d8107a4061a3543e1c33fbd2829/mct-21-0848-html.html
journals.lww.com journals.lww.com

Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.344840
  
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journals.lww.com/nrronline/Fulltext/2023/01000/Icariin_ameliorates_memory_deficits_through.39.aspx
May 2022
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Translational Strategies for Repotrectinib in Neuroblastoma

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1. scibot 05 May 2022
  
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  DOI: 10.1158/1535-7163.MCT-21-0126
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8571000/
Mar 2022
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Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells

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1. scibot 23 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110548
  
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sciencedirect.com/science/article/pii/S2211124722002893
Dec 2021
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BPS Publications

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1. scibot 21 Dec 2021
  
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  DOI: 10.1111/bph.15693
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15693
Aug 2021
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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.10.013
  
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sciencedirect.com/science/article/pii/S1074761318304783
Jul 2021
jcs.biologists.org jcs.biologists.org

The Parkinson's gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3

1
1. scibot 31 Jul 2021
  
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  PI3-kinase p85α
  
  DOI: 10.1242/jcs.233221
  
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  Curator: @Naa003
  
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jcs.biologists.org/content/132/20/jcs233221
May 2021
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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

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1. scibot 26 May 2021
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.celrep.2021.109161
  
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sciencedirect.com/science/article/pii/S2211124721005039
Apr 2021
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Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

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1. scibot 13 Apr 2021
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.cell.2021.03.031
  
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sciencedirect.com/science/article/pii/S0092867421003627
Sep 2020
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Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy

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1. scibot 08 Sep 2020
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.immuni.2020.07.011
  
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  RRID:AB_659889 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761320303186
www.cell.com www.cell.com

Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab

1
1. scibot 04 Sep 2020
  
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  PI3K
  
  DOI: 10.1016/j.celrep.2020.01.012
  
  Resource: (Cell Signaling Technology Cat# 4257, RRID:AB_659889)
  
  Curator: @ethanbadger
  
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cell.com/cell-reports/abstract/S2211-1247(20)30021-8
Jan 2020
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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.cmet.2019.05.016
  
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  Curator: @ethanbadger
  
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  RRID:AB_659889 RRIDCUR:Validated
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30256-6
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

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1. scibot 13 Jan 2020
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.cell.2019.09.008
  
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sciencedirect.com/science/article/pii/S0092867419310141
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Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection

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1. scibot 13 Jan 2020
  
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  RRID:AB_659889
  
  DOI: 10.1016/j.immuni.2019.11.015
  
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sciencedirect.com/science/article/pii/S1074761319304960
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_659889
  
  DOI: 10.1111/bph.14626
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14626
Nov 2018
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Curcumin Attenuates gp120-Induced Microglial Inflammation by Inhibiting Autophagy via the PI3K Pathway

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1. scibot 05 Nov 2018
  
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  AB_659889
  
  Curator: @evieth
  
  Curator note: Cell Signaling Technology Cat# 4257, Rabbit Anti-PI3 Kinase p85 Monoclonal Antibody, Unconjugated, Clone 19H8
  
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link.springer.com/article/10.1007/s10571-018-0616-3
academic.oup.com academic.oup.com

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_659889
  
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academic.oup.com/endo/article/159/9/3132/5050928
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EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation

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1. scibot 05 Nov 2018
  
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  RRID:AB_659889
  
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sciencedirect.com/science/article/pii/S1097276518302211