44 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway
    1
    1. scibot 23 May 2024
      RRID:AB_659940

      DOI: 10.1016/j.isci.2024.109829

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    ncbi.nlm.nih.gov/pmc/articles/PMC11103377/
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    MTCH2 stimulates cellular proliferation and cycles via PI3K/Akt pathway in breast cancer
    1
    1. scibot 21 Mar 2024
      RRID:AB_659940

      DOI: 10.1016/j.heliyon.2024.e28172

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    sciencedirect.com/science/article/pii/S2405844024042038
  5. Feb 2024
  6. link.springer.com link.springer.com
    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
    1
    1. scibot 22 Feb 2024
      RRID:AB_659940

      DOI: 10.1007/s12010-024-04887-6

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    link.springer.com/article/10.1007/s12010-024-04887-6
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ibrutinib-induced pulmonary angiotensin-converting enzyme activation promotes atrial fibrillation in rats
    1
    1. scibot 16 Feb 2024
      RRID:_AB_659940

      DOI: 10.1016/j.isci.2024.108926

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864204/
  8. Jan 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
    1
    1. scibot 18 Jan 2024
      RRID:AB_659940

      DOI: 10.1016/j.isci.2023.108725

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788290/
  10. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
    1
    1. scibot 11 Jan 2024
      RRID:AB_659940

      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  11. Aug 2023
  12. link.springer.com link.springer.com
    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
    1
    1. scibot 16 Aug 2023
      RRID:AB_659940

      DOI: 10.1007/s10967-023-09067-0

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    link.springer.com/article/10.1007/s10967-023-09067-0
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
    1
    1. scibot 27 Jul 2023
      RRID:AB_659940

      DOI: 10.1016/j.celrep.2023.112869

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    sciencedirect.com/science/article/pii/S221112472300880X
  15. www.sciencedirect.com www.sciencedirect.com
    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
    1
    1. scibot 21 Jul 2023
      RRID:AB_659940

      DOI: 10.1016/j.isci.2023.107341

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    sciencedirect.com/science/article/pii/S2589004223014189
  16. www.sciencedirect.com www.sciencedirect.com
    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
    1
    1. scibot 21 Jul 2023
      RRID:AB_659940

      DOI: 10.1016/j.celrep.2023.112794

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    sciencedirect.com/science/article/pii/S2211124723008057
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
    1
    1. scibot 12 Jul 2023
      RRID:AB_659940

      DOI: 10.1126/sciadv.adg9593

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    ncbi.nlm.nih.gov/pmc/articles/PMC10328411/
  18. Jun 2023
  19. 52.53.155.43 52.53.155.43
    Endothelial MRs mediate Western diet-induced lipid disorders and skeletal muscle insulin resistance in females
    1
    1. scibot 15 Jun 2023
      RRID:AB_659940

      DOI: 10.1210/endocr/bqad091

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    52.53.155.43/505020cd5ddad21196b5171a72c7e74f4f7d8201/bqad091-html.html
  20. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 01 Jun 2023
      RRID:AB_659940

      DOI: 10.1111/bph.16080

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
  21. Mar 2023
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA INPP5F ameliorates stress-induced hypertension via the miR-335/Cttn axis in rostral ventrolateral medulla
    1
    1. scibot 01 Mar 2023
      RRID:AB_659940

      DOI: 10.1111/cns.14142

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    onlinelibrary.wiley.com/doi/10.1111/cns.14142
  23. Dec 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis
    1
    1. scibot 17 Dec 2022
      RRID:AB_659940

      DOI: 10.1016/j.cmet.2022.11.012

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    sciencedirect.com/science/article/pii/S1550413122005034
  25. Nov 2022
  26. link.springer.com link.springer.com
    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
    1
    1. scibot 05 Nov 2022
      RRID:AB_659940

      DOI: 10.1007/s13402-022-00737-x

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    link.springer.com/article/10.1007/s13402-022-00737-x
  27. Sep 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
    1
    1. scibot 30 Sep 2022
      RRID:AB_659940

      DOI: 10.3389/fimmu.2022.931087

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  29. Jul 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell
    1
    1. scibot 30 Jul 2022
      AB_659940

      DOI: 10.1186/s13048-022-01021-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC9316729/
  31. Jun 2022
  32. 52.53.155.43 52.53.155.43
    mct-21-0848-html.html
    1
    1. scibot 30 Jun 2022
      RRID:AB_659940

      DOI: 10.1158/1535-7163.mct-21-0848

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    52.53.155.43/12e7b7b771463d8107a4061a3543e1c33fbd2829/mct-21-0848-html.html
  33. journals.lww.com journals.lww.com
    Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research
    1
    1. scibot 24 Jun 2022
      RRID:AB_659940

      DOI: 10.4103/1673-5374.344840

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    journals.lww.com/nrronline/Fulltext/2023/01000/Icariin_ameliorates_memory_deficits_through.39.aspx
  34. May 2022
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HDAC inhibition prevents hypobaric hypoxia‐induced spatial memory impairment through PΙ3K/GSK3β/CREB pathway
    1
    1. scibot 28 May 2022
      phosphor‐PI3K

      DOI: 10.1002/jcp.30337

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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.30337
  36. Mar 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
    1
    1. scibot 23 Mar 2022
      RRID:AB_659940

      DOI: 10.1016/j.celrep.2022.110548

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    sciencedirect.com/science/article/pii/S2211124722002893
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury
    1
    1. scibot 09 Mar 2022
      AB_659940

      DOI: 10.3389/fimmu.2022.837497

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    ncbi.nlm.nih.gov/pmc/articles/PMC8899187/
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 02 Mar 2022
      RRID:AB_2630365

      DOI: 10.1111/bph.15733

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15733
  40. Dec 2021
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 21 Dec 2021
      RRID:AB_659940

      DOI: 10.1111/bph.15693

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15693
  42. Jul 2021
  43. jcs.biologists.org jcs.biologists.org
    The Parkinson's gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3
    1
    1. scibot 31 Jul 2021
      P-PI3-kinase p85Tyr458/p55Tyr199

      DOI: 10.1242/jcs.233221

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    jcs.biologists.org/content/132/20/jcs233221
  44. May 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
    1
    1. scibot 08 May 2021
      RRID:AB_659940

      DOI: 10.1016/j.neuron.2021.03.008

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    sciencedirect.com/science/article/pii/S0896627321001562
  46. Feb 2021
  47. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 25 Feb 2021
      AB_659940

      DOI: 10.1111/bph.15047

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15047
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle
    1
    1. scibot 24 Feb 2021
      AB_659940

      DOI: 10.1002/jcb.29312

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    onlinelibrary.wiley.com/doi/10.1002/jcb.29312
  49. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
    1
    1. scibot 24 Feb 2021
      RRID:AB_659940

      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  50. Dec 2020
  51. link.springer.com link.springer.com
    Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death
    1
    1. scibot 07 Dec 2020
      Phospho-PI3 Kinase p85

      DOI: 10.1007/s10495-020-01645-x

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    link.springer.com/article/10.1007/s10495-020-01645-x
  52. Sep 2020
  53. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
    1
    1. scibot 23 Sep 2020
      RRID:AB_659940

      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  54. www.sciencedirect.com www.sciencedirect.com
    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
    1
    1. scibot 11 Sep 2020
      RRID:AB_659940

      DOI: 10.1016/j.bcp.2020.113949

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    sciencedirect.com/science/article/pii/S0006295220301775
  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 10 Sep 2020
      RRID:AB_659940

      DOI: 10.1111/bph.14918

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14918
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 09 Sep 2020
      RRID:AB_659940

      DOI: 10.1111/bph.15042

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15042
  57. www.mdpi.com www.mdpi.com
    Looking for a Better Characterization of Triple-Negative Breast Cancer by Means of Circulating Tumor Cells
    1
    1. scibot 04 Sep 2020
      anti-pPI3K

      DOI: 10.3390/jcm9020353

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    mdpi.com/2077-0383/9/2/353
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection
    1
    1. scibot 13 Jan 2020
      RRID:AB_659940

      DOI: 10.1016/j.immuni.2019.11.015

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    sciencedirect.com/science/article/pii/S1074761319304960
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA MEG3 contributes to adenosine‐induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K‐AKT‐mTOR and beclin‐1 signaling pathway
    1
    1. scibot 13 Jan 2020
      RRID:AB_659940

      DOI: 10.1002/jcb.29123

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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.29123
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.14626

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  62. Nov 2018
  63. link.springer.com link.springer.com
    Curcumin Attenuates gp120-Induced Microglial Inflammation by Inhibiting Autophagy via the PI3K Pathway
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      Curator: @evieth

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  65. www.sciencedirect.com www.sciencedirect.com
    Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity
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  66. Nov 2017
  67. academic.oup.com academic.oup.com
    Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice
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    Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model
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