Hypothesis

32 Matching Annotations

Mar 2026
www.sciencedirect.com www.sciencedirect.com

Hijacking ERAD for targeted degradation of transmembrane proteins

1
1. scibot 20 Mar 2026
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.cell.2026.01.018
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867426001054
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

1-s2.0-S2589004226002919-main-html.html

1
1. scibot 12 Feb 2026
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.isci.2026.114916
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12936848/
Jan 2026
www.nature.com www.nature.com

PDZRN4 suppresses lung adenocarcinoma progression via inhibiting ubiquitin-mediated HIF-1A degradation

1
1. scibot 06 Jan 2026
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1038/s41388-025-03670-z
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

nature.com/articles/s41388-025-03670-z
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Liquid-liquid phase separation of ATXN2L enhances mRNA translation in hepatocellular carcinoma

1
1. scibot 22 Nov 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2025.116588
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725013609
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CNOT7 facilitates radiation resistance in colorectal cancer through TRIM21/XRCC6-mediated non-homologous end joining repair

1
1. scibot 20 Nov 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1038/s41419-025-08160-4
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12623751/
Aug 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 19 Aug 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1111/bph.70171
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70171
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:AB_671
  
  DOI: 10.1158/0008-5472.CAN-24-3525
  
  Resource: None
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRIDCUR:Unresolved

RRID:AB_671515

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12314509/
Jul 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 30 Jul 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1111/bph.70122
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70122
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 functionality

1
1. scibot 28 Feb 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.isci.2025.112025
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004225002858
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation

1
1. scibot 17 Jan 2025
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2024.115215
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724015663
Dec 2024
www.sciencedirect.com www.sciencedirect.com

LINC00323 knockdown suppresses the proliferation, migration, and vascular mimicry of non-small cell lung cancer cells by promoting ubiquitinated degradation of AKAP1

1
1. scibot 17 Dec 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.ncrna.2024.12.006
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2468054024001707
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice

1
1. scibot 21 Nov 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1038/s44318-024-00263-6
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11574178/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Ubiquitin-mediated degradation of SlPsbS regulates low night temperature tolerance in tomatoes

1
1. scibot 25 Sep 2024
  
  in Public
  
  AB_671515
  
  DOI: 10.1016/j.celrep.2024.114757
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724011082
www.sciencedirect.com www.sciencedirect.com

Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2024.114691
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724010428
www.sciencedirect.com www.sciencedirect.com

Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells

1
1. scibot 04 Sep 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.heliyon.2024.e37227
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405844024132586
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

1
1. scibot 16 Apr 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2024.114111
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472400439X
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop

1
1. scibot 07 Mar 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1038/s12276-024-01190-6
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10985079/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

1
1. scibot 29 Feb 2024
  
  in Public
  
  AB_671515
  
  DOI: 10.1128/jvi.01726-23
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
www.sciencedirect.com www.sciencedirect.com

Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction

1
1. scibot 02 Feb 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.lfs.2024.122474
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0024320524000638
Jan 2024
www.sciencedirect.com www.sciencedirect.com

HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling

1
1. scibot 25 Jan 2024
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.yexcr.2024.113949
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0014482724000399
Nov 2023
www.sciencedirect.com www.sciencedirect.com

E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2023.113477
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014894
Oct 2023
www.cell.com www.cell.com

CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signalling pathway

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.isci.2023.108070
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

cell.com/iscience/abstract/S2589-0042(23)02147-8
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis

1
1. scibot 25 Jul 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.4103/1673-5374.371366
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10360089/
May 2023
www.sciencedirect.com www.sciencedirect.com

Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation

1
1. scibot 25 May 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.isci.2023.106852
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S258900422300929X
Apr 2023
www.sciencedirect.com www.sciencedirect.com

SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions

1
1. scibot 06 Apr 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2023.112339
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723003509
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

1
1. scibot 28 Mar 2023
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.celrep.2023.112309
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723003200
Feb 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat

1
1. scibot 01 Feb 2023
  
  in Public
  
  AB_671515
  
  DOI: 10.1002/jnr.25170
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jnr.25170
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

1
1. scibot 04 Nov 2022
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1016/j.isci.2022.105363
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9626688/
Aug 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low‐dose cisplatin exposure

1
1. scibot 01 Aug 2021
  
  in Public
  
  AB_671515
  
  DOI: 10.1096/fj.201901412R
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_671515

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1096/fj.201901412R
Jul 2021
elifesciences.org elifesciences.org

USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

1
1. scibot 29 Jul 2021
  
  in Public
  
  Ubiquitin Rabbit Polyclonal antibody
  
  DOI: 10.7554/eLife.48318
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_671515

Annotators

scibot

URL

elifesciences.org/articles/48318
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

α-synuclein strains that cause distinct pathologies differentially inhibit proteasome

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.7554/eLife.56825
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515
Visit annotations in context

Tags

RRID:AB_671515

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7406352/
Jan 2020
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Hydrogen sulfide regulates muscle RING finger‐1 protein S‐sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_671515
  
  DOI: 10.1111/bph.14601
  
  Resource: (Proteintech Cat# 10201-2-AP, RRID:AB_671515)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_671515
  
  What is this?
  
  RRID:AB_671515 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_671515

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14601