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30 Matching Annotations

Sep 2025
www.sciencedirect.com www.sciencedirect.com

α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation

1
1. scibot 11 Sep 2025
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.molcel.2025.08.022
  
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sciencedirect.com/science/article/pii/S1097276525007075
Jun 2025
link.springer.com link.springer.com

Temporal progression of pathological features in an α-synuclein overexpression model of Parkinson’s disease

1
1. scibot 11 Jun 2025
  
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  RRID:AB_727020
  
  DOI: 10.1007/s00429-025-02959-9
  
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link.springer.com/article/10.1007/s00429-025-02959-9
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma

1
1. scibot 16 Apr 2025
  
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  RRID:AB_727020
  
  DOI: 10.1126/sciadv.adq2519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980859/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner

1
1. scibot 05 Apr 2025
  
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  RRID:AB_727020
  
  DOI: 10.3389/fonc.2025.1554059
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11967197/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils

1
1. scibot 26 Feb 2025
  
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  RRID:AB_727020
  
  DOI: 10.1038/s42003-025-07680-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11846974/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner

1
1. scibot 21 Dec 2024
  
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  RRID:AB_727020
  
  DOI: 10.1101/2024.12.01.626256
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11642733/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms

1
1. scibot 21 Dec 2024
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.xpro.2024.103447
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609654/
www.researchsquare.com www.researchsquare.com

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1
1. scibot 20 Dec 2024
  
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  RRID:AB_727020
  
  DOI: 10.21203/rs.3.rs-1885484/v1
  
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researchsquare.com/article/rs-7289882/'https://www.researchsquare.com/article/rs-7289882/v1
Aug 2024
academic.oup.com academic.oup.com

Neuropathology and morphometry of dentate nucleus neurons in DYT1 brains: Cerebellar abnormalities in isolated dystonia

1
1. scibot 13 Aug 2024
  
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  Ab27766; Abcam
  
  DOI: 10.1093/jnen/nlad044
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @abever99
  
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academic.oup.com/jnen/article-abstract/82/8/695/7205924
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Imaging α-synuclein pathologies in animal models and patients with Parkinson’s and related diseases

1
1. scibot 06 Jun 2024
  
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  AB_727020
  
  DOI: 10.1016/j.neuron.2024.05.006
  
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sciencedirect.com/science/article/pii/S0896627324003325
May 2024
www.biorxiv.org www.biorxiv.org

Sex-focused analyses of M83 A53T hemizygous mouse model with recombinant human alpha-synuclein preformed fibril injection identifies female resilience to disease progression: A combined magnetic resonance imaging and behavioural study

1
1. scibot 30 May 2024
  
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  RRID:AB_727020
  
  DOI: 10.1101/2024.05.24.595642
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
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biorxiv.org/content/10.1101/2024.05.24.595642v1
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Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies

1
1. scibot 21 May 2024
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.neuron.2024.05.003
  
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sciencedirect.com/science/article/pii/S0896627324003283
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats with α-synucleinopathy

1
1. scibot 01 May 2024
  
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  RRID:AB_727020
  
  DOI: 10.4103/1673-5374.391190
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11040301/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Metabolic rescue of α-synuclein-induced neurodegeneration through propionate supplementation and intestine-neuron signaling in C. elegans

2
1. scibot 27 Feb 2024
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.celrep.2024.113865
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
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  RRID:AB_727020
2. scibot 27 Feb 2024
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.celrep.2024.113865
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
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  SciCrunch record: RRID:AB_727020
  
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sciencedirect.com/science/article/pii/S2211124724001931
Oct 2023
www.sciencedirect.com www.sciencedirect.com

α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity

1
1. scibot 17 Oct 2023
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.celrep.2023.113244
  
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sciencedirect.com/science/article/pii/S2211124723012561
Sep 2022
link.springer.com link.springer.com

Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo

1
1. scibot 20 Sep 2022
  
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  RRID:AB_727020
  
  DOI: 10.1007/s00401-022-02491-8
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @scibot
  
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link.springer.com/article/10.1007/s00401-022-02491-8
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Alpha-Synuclein Autoimmune Decline in Prodromal Multiple System Atrophy and Parkinson’s Disease

1
1. scibot 25 Jun 2022
  
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  RRID:AB_727020
  
  DOI: 10.3390/ijms23126554
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @scibot
  
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  RRID:AB_727020
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ncbi.nlm.nih.gov/pmc/articles/PMC9224313/
52.53.155.43 52.53.155.43

Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity

1
1. scibot 23 Jun 2022
  
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  AB_727020
  
  DOI: 10.3390/cancers14061382
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @scibot
  
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  RRID:AB_727020
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52.53.155.43/4deaece5f576ac127195ceba06752c88cfcd6756/cancers-14-01382-v2-html.html
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

1
1. scibot 18 Nov 2021
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.neuron.2021.10.032
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
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sciencedirect.com/science/article/pii/S089662732100862X
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Therapeutic potential of iron modulating drugs in a mouse model of multiple system atrophy

1
1. scibot 17 Sep 2021
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.nbd.2021.105509
  
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sciencedirect.com/science/article/pii/S0969996121002588
May 2021
www.sciencedirect.com www.sciencedirect.com

Cerebrospinal fluid and plasma distribution of anti-α-synuclein IgMs and IgGs in Multiple System Atrophy and Parkinson’s disease

1
1. scibot 15 May 2021
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.parkreldis.2021.05.001
  
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sciencedirect.com/science/article/pii/S1353802021001644
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue

1
1. scibot 09 Mar 2021
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.xpro.2021.100372
  
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sciencedirect.com/science/article/pii/S2666166721000794
Sep 2020
insight.jci.org insight.jci.org

Identification of Alzheimer’s disease–associated rare coding variants in the <i>ECE2</i> gene

1
1. scibot 04 Sep 2020
  
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  α-synuclein
  
  DOI: 10.1172/jci.insight.135119
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_727020
  
  Curator comments: Mouse Anti-Human alpha Synuclein Monoclonal Antibody, Unconjugated, Clone LB 509 Abcam Cat# ab27766
  
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  RRID:AB_727020 RRIDCUR:Missing
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RRID:AB_727020

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insight.jci.org/articles/view/135119
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.cels.2019.07.010
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_727020
  
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  RRID:AB_727020 RRIDCUR:Validated
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RRID:AB_727020

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sciencedirect.com/science/article/pii/S2405471219302674
www.frontiersin.org www.frontiersin.org

Distinct Autoimmune Anti-α-Synuclein Antibody Patterns in Multiple System Atrophy and Parkinson’s Disease

1
1. scibot 13 Jan 2020
  
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  RRID:AB_727020
  
  DOI: 10.3389/fimmu.2019.02253
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @Naa003
  
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  RRID:AB_727020 RRIDCUR:Validated
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frontiersin.org/articles/10.3389/fimmu.2019.02253/full
www.sciencedirect.com www.sciencedirect.com

Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein

1
1. scibot 13 Jan 2020
  
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  RRID:AB_727020
  
  DOI: 10.1016/j.neuron.2019.09.001
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_727020
  
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  RRID:AB_727020 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627319307743
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_727020
  
  DOI: 10.1016/j.celrep.2019.01.015
  
  Resource: (Abcam Cat# ab27766, RRID:AB_727020)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_727020
  
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  RRID:AB_727020 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719300233
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide

1
1. scibot 05 Nov 2018
  
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  RRID:AB_727020
  
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sciencedirect.com/science/article/pii/S0896627317311352
Nov 2017
link.springer.com link.springer.com

Synuclein expression in the lizard Anolis carolinensis

1
1. scibot 08 Nov 2017
  
  in Public
  
  ab27766
  
  Curator: @gabimpine
  
  Resource used:
  
  (Abcam Cat# ab27766, RRID:AB_727020)
  
  SciCrunch record: RRID:AB_727020
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_727020 RRIDCUR:Missing
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link.springer.com/article/10.1007/s00359-016-1108-x