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Feb 2026
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Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.stem.2026.01.002
  
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sciencedirect.com/science/article/pii/S1934590926000251
Jan 2026
54.241.53.176 54.241.53.176

2026.01.19.700398v1.full-html.html

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1. scibot 27 Jan 2026
  
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  DOI: 10.64898/2026.01.19.700398
  
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54.241.53.176/920dac77fb602c31bea028e2a56d4a986d400748/2026.01.19.700398v1.full-html.html
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MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.019
  
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sciencedirect.com/science/article/pii/S0092867425014321
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Empty spiracles homeobox 2 (EMX2) transcription factor functions as a tumor suppressor in renal cell carcinoma by targeting CADM1

1
1. scibot 22 Jan 2026
  
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  DOI: 10.1158/1541-7786.MCR-24-0496
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12807814/
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Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer

1
1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.014
  
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sciencedirect.com/science/article/pii/S1535610825005483
Dec 2025
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SIRT2 regulates the SMARCB1 loss-driven differentiation block in ATRT

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1. scibot 06 Dec 2025
  
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  DOI: 10.1158/1541-7786.MCR-24-0926
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12133431/
Nov 2025
54.241.53.176 54.241.53.176

2025.11.15.688565v1.full-html.html

1
1. scibot 22 Nov 2025
  
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  DOI: 10.1101/2025.11.15.688565
  
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54.241.53.176/3259fae050498259be3938591f9171ada23644a0/2025.11.15.688565v1.full-html.html
Oct 2025
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Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

1
1. scibot 14 Oct 2025
  
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  DOI: 10.7554/eLife.106814
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12490860/
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Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma

1
1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.drup.2025.101312
  
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sciencedirect.com/science/article/pii/S1368764625001153
Jul 2025
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Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors

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1. scibot 22 Jul 2025
  
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  DOI: 10.1126/sciadv.adw5228
  
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science.org/doi/10.1126/sciadv.adw5228
52.53.155.43 52.53.155.43

1-s2.0-S2589004225013215-main-html.html

1
1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113060
  
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52.53.155.43/f7de3ac929f9dcf0b46f3534fc31af712bb2cc52/1-s2.0-S2589004225013215-main-html.html
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Neutralization of acyl coenzyme A binding protein for the experimental prevention and treatment of hepatocellular carcinoma

1
1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102232
  
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sciencedirect.com/science/article/pii/S2666379125003052
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Chromosomal tethering and mitotic transcription promote ecDNA nuclear inheritance

1
1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.013
  
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sciencedirect.com/science/article/pii/S1097276525005428
May 2025
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Bifunctional transcription factor GhMYB4 orchestrates transition from elongation to secondary cell wall synthesis trade-off in cotton fiber

1
1. scibot 31 May 2025
  
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  DOI: 10.1016/j.devcel.2025.05.004
  
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1-s2.0-S2589004225008168-main-html.html

1
1. scibot 18 May 2025
  
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  RRID:AB_731658
  
  DOI: 10.1016/j.isci.2025.112555
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
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Lymphatic endothelial mTORC1 instructs metabolic and developmental signaling during lymphangiogenesis

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.012
  
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sciencedirect.com/science/article/pii/S1534580725002503
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Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis

1
1. scibot 17 May 2025
  
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  AB_731658
  
  DOI: 10.1016/j.ccell.2025.04.013
  
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sciencedirect.com/science/article/pii/S1535610825001722
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Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115657
  
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sciencedirect.com/science/article/pii/S2211124725004280
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Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115603
  
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sciencedirect.com/science/article/pii/S2211124725003742
Apr 2025
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PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc

1
1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115617
  
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sciencedirect.com/science/article/pii/S2211124725003882
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

1
1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115595
  
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sciencedirect.com/science/article/pii/S2211124725003663
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 26 Mar 2025
  
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52.53.155.43/e796403114c957ce0191bc2a029a1689cb8b887b/PDF-html.html
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 26 Mar 2025
  
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  RRID:AB_731658
  
  DOI: 10.1101/2025.03.14.643362
  
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52.53.155.43/4904a6ac570ee0a188db9dcfa738bde65420458f/PDF-html.html
Feb 2025
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Pre-clinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms (MPN) transformed to AML

1
1. scibot 20 Feb 2025
  
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  RRID:AB_731658
  
  DOI: 10.1182/blood.2024026388
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811934/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225003177-main-html.html

1
1. scibot 20 Feb 2025
  
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  RRID:AB_731658
  
  DOI: 10.1016/j.isci.2025.112057
  
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52.53.155.43/1e4a5f59d3666bbe659fe1b26d7fbe8060034304/1-s2.0-S2589004225003177-main-html.html
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HnRNPAB promotes pancreatic ductal adenocarcinoma extravasation and liver metastasis by stablizing MYC mRNA

1
1. scibot 14 Feb 2025
  
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  RRID:AB_731658
  
  DOI: 10.1158/1541-7786.MCR-24-0110
  
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aacrjournals.org/mcr/article/22/11/1022/749159/hnRNPAB-Promotes-Pancreatic-Ductal-Adenocarcinoma
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Lactate controls cancer stemness and plasticity through epigenetic regulation

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.002
  
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cell.com/cell-metabolism/fulltext/S1550-4131(25)00002-6
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MYC and HSF1 Cooperate to Drive Sensitivity to Polo-like Kinase 1 Inhibitor Volasertib in High-grade Serous Ovarian Cancer

1
1. scibot 08 Feb 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0400
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11799878/
52.53.155.43 52.53.155.43

PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc

1
1. scibot 06 Feb 2025
  
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  DOI: 10.1101/2024.09.05.611538
  
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52.53.155.43/15e44188d52367f113b80590d3658c7c4b4df9b2/2024.09.05.611538v1.full-html.html
Jan 2025
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Mitochondrial uncouplers inhibit oncogenic E2F1 activity and prostate cancer growth

1
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  DOI: 10.1016/j.xcrm.2024.101890
  
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sciencedirect.com/science/article/pii/S266637912400661X
Dec 2024
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Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

1
1. scibot 13 Dec 2024
  
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  DOI: 10.1038/s44321-024-00161-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
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Cell competition drives bronchiolization and pulmonary fibrosis

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  DOI: 10.1038/s41467-024-54997-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11621346/
Nov 2024
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ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

1
1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.cmet.2024.10.015
  
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Deciphering the composition and key driver genes of breast invasive micropapillary carcinoma by multi-omics analysis

1
1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111178
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549989/
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Dysregulation of R-loop homeostasis shapes the immunosuppressive microenvironment and induces malignant progression in melanoma

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1. scibot 07 Nov 2024
  
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  DOI: 10.1007/s10495-024-02039-z
  
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Oct 2024
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MYC is Sufficient to Generate Mid-Life High-Grade Serous Ovarian and Uterine Serous Carcinomas in a p53-R270H Mouse Model

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Aug 2024
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Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II

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Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease

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Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis

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Jul 2024
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1-s2.0-S1535610824002319-mmc1-html.html

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Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

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Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer

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May 2024
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Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

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Cell competition drives bronchiolization and pulmonary fibrosis

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Myc promotes polyploidy in murine trophoblast cells and suppresses senescence

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Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

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The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex

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Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer

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Apr 2024
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Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation

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Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome

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Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma

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ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation

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Proteogenomic characterization of primary colorectal cancer and metastatic progression identifies proteome-based subtypes and signatures

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PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma

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Sirt6 regulates proliferation of neural precursor cells and cortical neurogenesis in mice

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Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

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Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

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Exosome-mediated delivery of miR-519e-5p promotes malignant tumor phenotype and CD8+ T-cell exhaustion in metastatic PTC

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Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling

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A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment

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LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation

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PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer

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MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS

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The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing

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ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells

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Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer

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Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer

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MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer

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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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Molecular Subtypes of Head and Neck Cancer in Patients of African Ancestry

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In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities

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Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation

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Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression

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An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets

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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin

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RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition

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The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming

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Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells

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m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis

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Feb 2023
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bcd-22-0082-html.html

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Jan 2023
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

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Immunoediting instructs tumor metabolic reprogramming to support immune evasion

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ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen

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The phenotypic landscape of essential human genes

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Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis

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FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits

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Integrative analysis reveals histone demethylase LSD1 promotes RNA polymerase II pausing

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Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis

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EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures

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Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway

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Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells

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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

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Feb 2022
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EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells

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MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma

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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

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In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration

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MYC amplifies gene expression through global changes in transcription factor dynamics

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Impact of intravesical instillation of a novel biological response modifier (P-MAPA) on progress of non-muscle invasive bladder cancer treatment in a rat model

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Dec 2021
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MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

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Nov 2021
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MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

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A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation

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USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma

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Oct 2021
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Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth

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Sep 2021
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Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer

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Cilium induction triggers differentiation of glioma stem cells

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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

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BPS Publications

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BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models

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Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

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Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11

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A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope

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MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages

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Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

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Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation

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Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

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Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer

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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

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Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis

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Impact of WIN site inhibitor on the WDR5 interactome

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HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies

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MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

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Nov 2020
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Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer

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Oct 2020
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m6A RNA methylation impacts fate choices during skin morphogenesis

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Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

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Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer

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MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

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A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

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Selective PP2A Enhancement through Biased Heterotrimer Stabilization

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Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

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MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities

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p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis

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Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma

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Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA

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Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis

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Gut microbiota from colorectal cancer patients enhances the progression of intestinal adenoma in Apcmin/+ mice

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The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth

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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

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Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

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Oncogenic MYC amplifies mitotic perturbations

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High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline

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Epiblast Formation by TEAD-YAP-Dependent Expression of Pluripotency Factors and Competitive Elimination of Unspecified Cells

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Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention

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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

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KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

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Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts

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Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

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Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques

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Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

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DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors

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Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import

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Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities

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Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma

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The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma

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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma

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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells

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Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding

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R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

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Untitled document

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continuumtest--journal.elifesciences.org continuumtest--journal.elifesciences.org

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc.

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continuumtest--journal.elifesciences.org/articles/30274
Nov 2017
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Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response

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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

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Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma

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Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma

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Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

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In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

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