294 Matching Annotations
  1. Aug 2025
  2. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
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    Structural insights into the activation of TMEM175 by small molecule
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    sciencedirect.com/science/article/pii/S0896627325005562
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Redistribution of fragmented mitochondria ensures symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12339001/
  5. Jul 2025
  6. 52.53.155.43 52.53.155.43
    watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
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    Protocol for visualization of ultrafine nuclear structures in cultured cells using protein retention expansion microscopy
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    sciencedirect.com/science/article/pii/S2666166725003910
  8. 52.53.155.43 52.53.155.43
    2025.07.14.664742v1.full-html.html
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    52.53.155.43/0ddeb0d5c1e9d78409db30015477d90afb34bbce/2025.07.14.664742v1.full-html.html
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
  10. Jun 2025
  11. link.springer.com link.springer.com
    RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis
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    link.springer.com/article/10.1186/s12964-025-02278-w
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    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/fulltext/S1550-4131(25)00265-7
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    Synaptic activity causes minute-scale changes in BAF complex composition and function
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    sciencedirect.com/science/article/pii/S1097276525004563
  14. May 2025
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    YTHDF1 differentiates the contributing roles of mTORC1 in aging
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    sciencedirect.com/science/article/pii/S1097276525004083
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    Integrative characterization of MYC RNA-binding function
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    sciencedirect.com/science/article/pii/S2666979X2500134X
  17. 52.53.155.43 52.53.155.43
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  18. Apr 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p53 regulates DREAM complex-mediated repression in a p21-independent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC12000331/
  20. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TCF19/CDKN2A Regulates Glycolysis and Macrophage M2 Polarization for Osteosarcoma Progression
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401343RRR
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    An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
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    sciencedirect.com/science/article/pii/S1097276525001996
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962390/
  23. Mar 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S2211124725001706
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    YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks
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    sciencedirect.com/science/article/pii/S109727652500108X
  26. Feb 2025
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    RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry
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    sciencedirect.com/science/article/pii/S0092867425001096
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    Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation
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    sciencedirect.com/science/article/pii/S1097276525000577
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    Progesterone Receptor Signaling Promotes Cancer Associated Fibroblast Mediated Tumorigenicity in ER+ Breast Cancer
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    dx.doi.org/10.1210/endocr/bqae092
  30. www.sciencedirect.com www.sciencedirect.com
    KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31
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    sciencedirect.com/science/article/pii/S1534580725000358
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization
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    pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Ref-1 redox activity regulates retinal neovascularization by modulating transcriptional activation of HIF-1α
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401989RR
  33. Jan 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coordination of Focal Adhesion Nanoarchitecture and Dynamics in Mechanosensing for Cardiomyoblast Differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11758775/
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    Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity
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    sciencedirect.com/science/article/pii/S1550413124004820
  36. Dec 2024
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  38. Nov 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Autophagy-dependent splicing control directs translation toward inflammation during senescence
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    sciencedirect.com/science/article/pii/S1534580724006270
  40. Sep 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11422717/
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    A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain
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    sciencedirect.com/science/article/pii/S2211124724011173
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
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    sciencedirect.com/science/article/pii/S1097276524007330
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    sciencedirect.com/science/article/pii/S1534580724004921
  45. Aug 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
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    Increased viral tolerance mediates by antiviral RNA interference in bat cells
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    sciencedirect.com/science/article/pii/S2211124724009100
  48. www.cell.com www.cell.com
    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
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    cell.com/action/showExperimentalProcedures
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22280/full
  50. Jul 2024
  51. www.sciencedirect.com www.sciencedirect.com
    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
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    sciencedirect.com/science/article/pii/S2666379124003732
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    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
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    sciencedirect.com/science/article/pii/S2666379124003616
  53. www.cell.com www.cell.com
    YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment
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    cell.com/cell-reports/abstract/S2211-1247(24)00785-X
  54. www.cell.com www.cell.com
    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
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    cell.com/cell/fulltext/S0092-8674(24)00693-7
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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    sciencedirect.com/science/article/pii/S0969996124001864
  56. Jun 2024
  57. www.sciencedirect.com www.sciencedirect.com
    An enhancer RNA recruits KMT2A to regulate transcription of Myb
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    sciencedirect.com/science/article/pii/S221112472400706X
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    Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy
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    sciencedirect.com/science/article/pii/S2211124724007058
  59. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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    elifesciences.org/articles/88375
  60. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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    sciencedirect.com/science/article/pii/S2666379124002842
  61. May 2024
  62. aacrjournals.org aacrjournals.org
    LINC00869 promotes hepatocellular carcinoma metastasis via protrusion formation
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    aacrjournals.org/mcr/article/22/3/282/734709/LINC00869-Promotes-Hepatocellular-Carcinoma
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    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
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    sciencedirect.com/science/article/pii/S2211124724005655
  64. Apr 2024
  65. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  67. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  68. 52.53.155.43 52.53.155.43
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  71. Mar 2024
  72. www.nature.com www.nature.com
    FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins
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    nature.com/articles/s41564-024-01646-5
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLR2 regulates hair follicle cycle and regeneration via BMP signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
  74. www.sciencedirect.com www.sciencedirect.com
    Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral response
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    sciencedirect.com/science/article/pii/S2211124724002109
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  76. Feb 2024
  77. 52.53.155.43 52.53.155.43
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human iPSC-derived closed-loop cardiac tissue for drug assessment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850789/
  79. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
  81. Jan 2024
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10192437/
  83. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    cell.com/cell-reports/abstract/S2211-1247(23)01438-9
  84. Dec 2023
  85. www.sciencedirect.com www.sciencedirect.com
    YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring
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    sciencedirect.com/science/article/pii/S2589004223027803
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    sciencedirect.com/science/article/pii/S2666379123005591
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    sciencedirect.com/science/article/pii/S221112472301553X
  88. www.sciencedirect.com www.sciencedirect.com
    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
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  89. link.springer.com link.springer.com
    Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
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    link.springer.com/article/10.1186/s12915-023-01773-1
  90. Nov 2023
  91. www.sciencedirect.com www.sciencedirect.com
    A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment
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    sciencedirect.com/science/article/pii/S2666379123004809
  92. www.sciencedirect.com www.sciencedirect.com
    Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2
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    sciencedirect.com/science/article/abs/pii/S2451945623003306
  93. Oct 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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    ncbi.nlm.nih.gov/pmc/articles/PMC10590974/
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    Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124723012238
  96. Sep 2023
  97. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    nature.com/articles/s41422-023-00874-4
  98. Aug 2023
  99. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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    52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
  100. Jul 2023
  101. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
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    sciencedirect.com/science/article/pii/S221112472300880X
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC10366467/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328411/
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    CRIC-seq protocol for in situ profiling of proximal RNA-RNA contacts associated with RNA-binding proteins
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    sciencedirect.com/science/article/pii/S2666166723003684
  105. Jun 2023
  106. www.sciencedirect.com www.sciencedirect.com
    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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    sciencedirect.com/science/article/pii/S2589004223011124
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    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
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  108. academic.oup.com academic.oup.com
    The Transmembrane Protein TM4SF3 Interacts with AR and AR-V7 and is Recruited to AR Target Genes
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    academic.oup.com/endo/article/164/5/bqad048/7084716
  109. May 2023
  110. link.springer.com link.springer.com
    Circular RNAs arising from synaptic host genes during human neuronal differentiation are modulated by SFPQ RNA-binding protein
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    link.springer.com/article/10.1186/s12915-023-01627-w
  111. 52.53.155.43 52.53.155.43
    BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage
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    The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity
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  220. Jun 2021
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    TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease
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  222. May 2021
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    Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
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  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
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    Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage
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    Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance
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    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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  228. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity
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  229. www.sciencedirect.com www.sciencedirect.com
    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
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    SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells
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  231. Apr 2021
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    Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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    Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation
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    Coordinate regulation of the senescent state by selective autophagy
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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
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    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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    Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells
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    A selective p53 activator and anticancer agent to improve colorectal cancer therapy
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