193 Matching Annotations
  1. Last 7 days
  2. journals.plos.org journals.plos.org
    Phosphorylation of SNAP-25 at Ser187 is enhanced following its cleavage by Botulinum Neurotoxin Serotype A, promoting the dominant-negative effect of the resulting fragment
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    journals.plos.org/plospathogens/article
  3. Sep 2025
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    Ablation of histone H1.4 reveals the focal regulation of AP-1 directed enhancers
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    sciencedirect.com/science/article/pii/S2589004225016876
  5. Aug 2025
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    Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex
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    sciencedirect.com/science/article/pii/S1097276525006136
  7. Jul 2025
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    Protocol for visualization of ultrafine nuclear structures in cultured cells using protein retention expansion microscopy
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    sciencedirect.com/science/article/pii/S2666166725003910
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    Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling
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    science.org/doi/10.1126/science.adm9805
  10. May 2025
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    Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain
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    sciencedirect.com/science/article/pii/S0092867425005082
  12. Mar 2025
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    Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S2211124725001706
  14. Dec 2024
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    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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    sciencedirect.com/science/article/pii/S2211124724013354
  16. Aug 2024
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22280/full
  18. Jul 2024
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    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
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    sciencedirect.com/science/article/pii/S2211124724008258
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    YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment
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    cell.com/cell-reports/abstract/S2211-1247(24)00785-X
  21. Jun 2024
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    An enhancer RNA recruits KMT2A to regulate transcription of Myb
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    sciencedirect.com/science/article/pii/S221112472400706X
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    Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes
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    sciencedirect.com/science/article/pii/S1074761324002620
  24. Apr 2024
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    TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
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    sciencedirect.com/science/article/pii/S1550413124001232
  26. Mar 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  28. Feb 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
  30. Dec 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10703791/
  32. Nov 2023
  33. www.nature.com www.nature.com
    PRO-IP-seq tracks molecular modifications of engaged Pol II complexes at nucleotide resolution
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    nature.com/articles/s41467-023-42715-3
  34. Sep 2023
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    NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism-mediated cancer radiotherapy
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    sciencedirect.com/science/article/pii/S2211124723011385
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    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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    sciencedirect.com/science/article/pii/S1534580723004380
  37. Jun 2023
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    A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy
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    sciencedirect.com/science/article/pii/S1097276523004331
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    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
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    sciencedirect.com/science/article/pii/S1097276523003714
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    The Transmembrane Protein TM4SF3 Interacts with AR and AR-V7 and is Recruited to AR Target Genes
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    academic.oup.com/endo/article/164/5/bqad048/7084716
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    The circadian clock CRY1 regulates pluripotent stem cell identity and somatic cell reprogramming
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    sciencedirect.com/science/article/pii/S2211124723006010
  42. May 2023
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    Zhx2 maintains islet β cell mass and function by transcriptionally regulating Pax6
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    sciencedirect.com/science/article/pii/S2589004223009483
  44. aacrjournals.org aacrjournals.org
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer
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    aacrjournals.org/cancerres/article/82/13/2458/705024/Transcriptional-Repression-by-FoxM1-Suppresses
  45. Apr 2023
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    Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
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    sciencedirect.com/science/article/pii/S2211124723003881
  47. Feb 2023
  48. www.science.org www.science.org
    Multiscale 3D genome reorganization during skeletal muscle stem cell lineage progression and aging
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    science.org/doi/10.1126/sciadv.abo1360
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiscale 3D genome reorganization during skeletal muscle stem cell lineage progression and aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC9937580/
  50. Jan 2023
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    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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    sciencedirect.com/science/article/pii/S2211124723000426
  52. Dec 2022
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    β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility
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    sciencedirect.com/science/article/pii/S2666379122003846
  54. Sep 2022
  55. www.nature.com www.nature.com
    Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
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    nature.com/articles/s41388-022-02450-3
  56. Jul 2022
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    Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA
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    sciencedirect.com/science/article/pii/S109727652200555X
  58. Jun 2022
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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    sciencedirect.com/science/article/pii/S2211124722006453
  60. May 2022
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    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
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    nature.com/articles/s41598-022-12188-3
  62. Apr 2022
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    Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
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    sciencedirect.com/science/article/pii/S2352396422001694
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    sciencedirect.com/science/article/pii/S2211124722003199
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    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
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    nature.com/articles/s41418-022-00983-4
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    Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis
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    aacrjournals.org/cancerres/article/82/7/1321/694048/Hotspot-ESR1-Mutations-Are-Multimodal-and
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  68. Mar 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator
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    sciencedirect.com/science/article/pii/S1874939922000165
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    Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8887898/
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    STAT3-mediated allelic imbalance of novel genetic variant rs1047643 and B cell specific super-enhancer in association with systemic lupus erythematosus
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    ncbi.nlm.nih.gov/pmc/articles/PMC8884724/
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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  73. Feb 2022
  74. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    sciencedirect.com/science/article/pii/S1097276522000879
  75. Jan 2022
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    Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1
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    sciencedirect.com/science/article/pii/S2211124721017496
  77. Dec 2021
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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    sciencedirect.com/science/article/pii/S221112472101634X
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    A novel CARM1-HuR axis involved in muscle differentiation and plasticity misregulated in spinal muscular atrophy
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab333/6428333
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    Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
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    sciencedirect.com/science/article/pii/S221112472101603X
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    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
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    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
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    sciencedirect.com/science/article/pii/S009286742101326X
  83. Oct 2021
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    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
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    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8517284/
  86. Sep 2021
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    Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK
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    sciencedirect.com/science/article/pii/S1097276521006924
  88. Aug 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6482433/
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    A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation
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    sciencedirect.com/science/article/pii/S1074761319300494
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    ncbi.nlm.nih.gov/pmc/articles/PMC5759774/
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    cell.com/molecular-cell/abstract/S1097-2765(17)30053-9
  94. Jul 2021
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    academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioy152/5050366
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    academic.oup.com/biolreprod/article/99/6/1303/5050366
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    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
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    embopress.org/doi/10.15252/embr.201948058
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    Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
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    sciencedirect.com/science/article/pii/S1931312818305432
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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
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    MEF2C Interacts With c-FOS in PTH-Stimulated Mmp13 Gene Expression in Osteoblastic Cells
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    academic.oup.com/endo/article/158/11/3778/3988136
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    Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8261663/
  104. Jun 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    lncRNA ILF3-AS1 promotes proliferation and metastasis of colorectal cancer cells by recruiting histone methylase EZH2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8167202/
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    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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    link.springer.com/article/10.1186/s13072-021-00403-w
  107. May 2021
  108. academic.oup.com academic.oup.com
    FSHB Transcription is Regulated by a Novel 5’ Distal Enhancer with a Fertility-Associated Single Nucleotide Polymorphism
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    academic.oup.com/endo/article/162/1/bqaa181/5917511
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    Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage
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    Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance
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    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
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    sciencedirect.com/science/article/pii/S1534580720305803
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    Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism
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    sciencedirect.com/science/article/pii/S1550413121000036
  113. Apr 2021
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    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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    sciencedirect.com/science/article/pii/S1550413120302473
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    Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
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    sciencedirect.com/science/article/pii/S1550413120303600
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function
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    ncbi.nlm.nih.gov/pmc/articles/PMC7997661/
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    Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor
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    sciencedirect.com/science/article/pii/S0304383521000926
  118. Mar 2021
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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    ncbi.nlm.nih.gov/pmc/articles/PMC7947244/
  120. Feb 2021
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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    sciencedirect.com/science/article/pii/S1550413120306665
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    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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    sciencedirect.com/science/article/pii/S0092867420316147
  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
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    onlinelibrary.wiley.com/doi/10.1002/dneu.22280/full
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    Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus
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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.33
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    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
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    sciencedirect.com/science/article/pii/S2211124721000620
  126. Jan 2021
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    HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies
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