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C9orf72-associated and sporadic FTD patient iPSC-microglia show differences in phagocytosis and gene expression

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1. scibot 08 Aug 2026
  
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  DOI: 10.1016/j.stemcr.2026.103026
  
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sciencedirect.com/science/article/pii/S2213671126002377
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sec61β maintains cytoplasmic proteostasis via ARIH1-mediated translational repression upon ER stress

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1. scibot 03 Mar 2026
  
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  DOI: 10.1038/s44319-026-00690-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12936171/
Jul 2025
rupress.org rupress.org

Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways

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1. scibot 30 Jul 2025
  
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  DOI: 10.1083/jcb.202312133
  
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rupress.org/jcb/article/224/9/e202312133/278137/Ubiquitin-chain-variability-directs-substrates-of
Dec 2024
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Reduced lung metastasis in endothelial cell-specific transforming growth factor β type II receptor-deficient mice with decreased CD44 expression

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111502
  
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sciencedirect.com/science/article/pii/S2589004224027299
Nov 2024
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Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

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1. scibot 14 Nov 2024
  
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  DOI: 10.7554/eLife.89606
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11556787/
Aug 2024
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Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume

1
1. scibot 30 Aug 2024
  
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  DOI: 10.1371/journal.pone.0309461
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11356391/
May 2024
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The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.019
  
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sciencedirect.com/science/article/pii/S1534580724002946
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Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor

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1. scibot 16 May 2024
  
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  DOI: 10.1007/s13577-024-01074-x
  
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link.springer.com/article/10.1007/s13577-024-01074-x
Apr 2024
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Protocol to detect OLA1 polyubiquitination by Aurora A in vivo and in vitro

2
1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.xpro.2024.103008
  
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2. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.xpro.2024.103008
  
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sciencedirect.com/science/article/pii/S2666166724001734
Nov 2023
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Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113451
  
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sciencedirect.com/science/article/pii/S2211124723014638
Jul 2023
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Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation

1
1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112850
  
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sciencedirect.com/science/article/pii/S2211124723008616
Jun 2023
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Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells

1
1. scibot 24 Jun 2023
  
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  DOI: 10.1016/j.chembiol.2023.05.012
  
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sciencedirect.com/science/article/pii/S2451945623001551
May 2023
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Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112520
  
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sciencedirect.com/science/article/pii/S2211124723005314
Apr 2023
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A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans

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1. scibot 20 Apr 2023
  
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  DOI: 10.1242/dev.201035
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10112894/
Feb 2023
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Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease

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1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.008
  
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sciencedirect.com/science/article/pii/S1074761323000183
Jan 2023
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Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles

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1. scibot 02 Jan 2023
  
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  DOI: 10.1016/j.neuron.2022.11.017
  
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sciencedirect.com/science/article/pii/S0896627322010716
Jun 2022
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CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110957
  
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sciencedirect.com/science/article/pii/S2211124722007392
Feb 2022
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway

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1. scibot 22 Feb 2022
  
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  DOI: 10.1096/fj.202101298R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101298R
Sep 2021
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SUMOylation of RepoMan during late telophase regulates dephosphorylation of lamin A

1
1. scibot 25 Sep 2021
  
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  DOI: 10.1242/jcs.247171
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8445599/
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The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila

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1. scibot 04 Sep 2021
  
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  AB_772207
  
  DOI: 10.1371/journal.pgen.1009744
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8412352/
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing

1
1. scibot 30 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.03.062
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8208822/
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Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

1
1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108999
  
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sciencedirect.com/science/article/pii/S2211124721003132
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Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation

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1. scibot 23 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.05.026
  
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sciencedirect.com/science/article/pii/S0092867420306218
Feb 2021
www.cell.com www.cell.com

Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.cub.2020.11.040
  
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cell.com/current-biology/abstract/S0960-9822(20)31752-8
Jan 2021
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A microtubule‐LUZP1 association around tight junction promotes epithelial cell apical constriction

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1. scibot 07 Jan 2021
  
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  RRID:AB_772207
  
  DOI: 10.15252/embj.2020104712
  
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embopress.org/doi/abs/10.15252/embj.2020104712
Dec 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes

1
1. scibot 30 Dec 2020
  
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  DOI: 10.1002/jnr.24775
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24775
Nov 2020
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CK2 Inhibits TIMELESS Nuclear Export and Modulates CLOCK Transcriptional Activity to Regulate Circadian Rhythms

1
1. scibot 28 Nov 2020
  
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  Goat anti-rat IgG-HRP
  
  DOI: 10.1016/j.cub.2020.10.061
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7878342/
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Prefrontal cortex miR‐874‐3p prevents lipopolysaccharide‐induced depression‐like behavior through inhibition of indoleamine 2,3‐dioxygenase 1 expression in mice.

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1. scibot 19 Nov 2020
  
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  DOI: 10.1111/jnc.15222
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15222
Oct 2020
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Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles

1
1. scibot 20 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108261
  
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sciencedirect.com/science/article/pii/S221112472031250X
Sep 2020
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Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107972
  
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sciencedirect.com/science/article/pii/S2211124720309530
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Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids

1
1. scibot 14 Sep 2020
  
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  RRID:AB_772207
  
  DOI: 10.3390/nu12082452
  
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mdpi.com/2072-6643/12/8/2452
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Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor

1
1. scibot 04 Sep 2020
  
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  NA935V
  
  DOI: 10.3390/ijms21155193
  
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  Curator: @Naa003
  
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  Curator comments: Goat Anti-Rat IgG, Whole Ab ECL Antibody, HRP Conjugated GE Healthcare Cat# NA935
  
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mdpi.com/1422-0067/21/15/5193
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Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

1
1. scibot 04 Sep 2020
  
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  RRID:AB_772207
  
  DOI: 10.1016/j.celrep.2020.01.107
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_772207
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sciencedirect.com/science/article/pii/S2211124720301510
Jan 2020
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Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.079
  
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A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster

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Untitled document

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Untitled document

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MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis

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PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites

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Establishment of DNA-DNA Interactions by the Cohesin Ring

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The Drosophila speciation factor HMR localizes to genomic insulator sites

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Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice

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Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B Infection

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