109 Matching Annotations
  1. Last 7 days
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    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    sciencedirect.com/science/article/pii/S1550413124004029
  3. Sep 2024
  4. 52.53.155.43 52.53.155.43
    Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease
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      DOI: 10.1101/2024.07.19.604372

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    52.53.155.43/094bf1894e7037610818c8319cb16bd0730a5b11/2024.07.19.604372v1.full-html.html
  5. Aug 2024
  6. www.embopress.org www.embopress.org
    The glycine arginine-rich domain of the RNA-binding protein nucleolin regulates its subcellular localization
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      DOI: 10.15252/embj.2020107158

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    embopress.org/doi/full/10.15252/embj.2020107158
  7. www.sciencedirect.com www.sciencedirect.com
    Sestrin2 drives ER-phagy in response to protein misfolding
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      DOI: 10.1016/j.devcel.2024.07.004

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    sciencedirect.com/science/article/pii/S1534580724004416
  8. Jun 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos
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      DOI: 10.1016/j.heliyon.2024.e32243

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    sciencedirect.com/science/article/pii/S2405844024082744
  10. May 2024
  11. www.biorxiv.org www.biorxiv.org
    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    1. scibot 10 May 2024
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      DOI: 10.1101/2024.01.25.577280

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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  12. link.springer.com link.springer.com
    Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules
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      DOI: 10.1007/s00018-024-05247-7

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    link.springer.com/article/10.1007/s00018-024-05247-7
  13. Feb 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Mouse oocytes sequester aggregated proteins in degradative super-organelles
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    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.031

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    sciencedirect.com/science/article/pii/S0092867424000680
  15. Jan 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.isci.2024.108801

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    sciencedirect.com/science/article/pii/S2589004224000221
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington’s disease
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      DOI: 10.1016/j.celrep.2023.113573

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    sciencedirect.com/science/article/pii/S2211124723015851
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    Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity
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    sciencedirect.com/science/article/pii/S2589004223025622
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113484

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    sciencedirect.com/science/article/pii/S2211124723014961
  22. www.sciencedirect.com www.sciencedirect.com
    Targeted down-regulation of SRSF1 exerts anti-cancer activity in OSCC through impairing lysosomal function and autophagy
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    sciencedirect.com/science/article/pii/S2589004223024070
  23. Oct 2023
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Trem2 deficiency attenuates microglial phagocytosis and autophagic-lysosomal activation in white matter hypoperfusion
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    1. scibot 20 Oct 2023
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      DOI: 10.1111/jnc.15987

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15987
  25. www.cell.com www.cell.com
    Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury
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    cell.com/iscience/abstract/S2589-0042(23)02138-7
  26. www.biorxiv.org www.biorxiv.org
    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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    1. scibot 13 Oct 2023
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      DOI: 10.1101/2023.10.06.560832

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    biorxiv.org/content/10.1101/2023.10.06.560832v1
  27. Sep 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Examining PI3K-signaling-dependent regulation of lens organelle free zone formation via immunolocalization and immunoblotting in chick embryos
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      DOI: 10.1016/j.xpro.2023.102569

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509694/
  29. www.sciencedirect.com www.sciencedirect.com
    Base editing corrects the common Salla disease SLC17A5 c.115C>T variant
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      DOI: 10.1016/j.omtn.2023.08.024

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    sciencedirect.com/science/article/pii/S2162253123002354
  30. Aug 2023
  31. www.sciencedirect.com www.sciencedirect.com
    The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
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    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.celrep.2023.113012

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    sciencedirect.com/science/article/pii/S2211124723010239
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel
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    1. scibot 30 Jun 2023
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      DOI: 10.1016/j.molcel.2023.06.004

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    sciencedirect.com/science/article/pii/S1097276523004264
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    SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
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    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.isci.2023.107118

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    sciencedirect.com/science/article/pii/S2589004223011951
  35. 52.53.155.43 52.53.155.43
    Apolipoprotein E intersects with amyloid-β within neurons
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      DOI: 10.26508/lsa.202201887

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      RRID:AB_775978

      DOI: 10.26508/lsa.202201887

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    52.53.155.43/d79c74abbe0299455dfcf8568ff6bf527c1e5b68/e202201887.full-html.html
  36. dx.doi.org dx.doi.org
    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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    1. scibot 08 Jun 2023
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      DOI: 10.1158/2159-8290.CD-22-0376

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    dx.doi.org/10.1158/2159-8290.CD-22-0376
  37. www.thelancet.com www.thelancet.com
    Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease
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      DOI: 10.1016/j.ebiom.2023.104628

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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00193-7/abstract
  38. May 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons
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    1. scibot 16 May 2023
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      DOI: 10.1523/JNEUROSCI.1356-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10175236/
  40. www.mdpi.com www.mdpi.com
    Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function
    1
    1. scibot 06 May 2023
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      DOI: 10.3390/cells10020413

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    mdpi.com/2073-4409/10/2/413/htm
  41. Mar 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Large neutral amino acid levels tune perinatal neuronal excitability and survival
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      DOI: 10.1016/j.cell.2023.02.037

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    sciencedirect.com/science/article/pii/S0092867423002155
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization
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      DOI: 10.1016/j.isci.2023.106274

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    ncbi.nlm.nih.gov/pmc/articles/PMC9957656/
  44. www.sciencedirect.com www.sciencedirect.com
    Coordination of non-professional efferocytosis and actomyosin contractility during epithelial tissue morphogenesis
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      DOI: 10.1016/j.celrep.2023.112202

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    sciencedirect.com/science/article/pii/S2211124723002139
  45. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Colchicine exerts anti-atherosclerotic and ‑plaque-stabilizing effects targeting foam cell formation
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      DOI: 10.1096/fj.202201469R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202201469R
  46. Feb 2023
  47. 52.53.155.43 52.53.155.43
    cd-22-0376-html.html
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      DOI: 10.1158/2159-8290.cd-22-0376

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    52.53.155.43/a051cdc9b66cfe47aeb3f39770c1ce7cd380afb2/cd-22-0376-html.html
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
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      DOI: 10.1016/j.cell.2023.01.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC10062012/
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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      DOI: 10.1016/j.celrep.2023.112037

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      DOI: 10.1016/j.celrep.2023.112037

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    sciencedirect.com/science/article/pii/S2211124723000487
  51. www.sciencedirect.com www.sciencedirect.com
    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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      DOI: 10.1016/j.celrep.2023.112002

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    sciencedirect.com/science/article/pii/S221112472300013X
  52. Dec 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
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      DOI: 10.1016/j.xpro.2022.101935

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    sciencedirect.com/science/article/pii/S2666166722008152
  54. Sep 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
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      DOI: 10.3389/fimmu.2022.931087

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  56. www.sciencedirect.com www.sciencedirect.com
    Microglial control of neuronal development via somatic purinergic junctions
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      DOI: 10.1016/j.celrep.2022.111369

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    sciencedirect.com/science/article/pii/S2211124722012013
  57. www.sciencedirect.com www.sciencedirect.com
    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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      DOI: 10.1016/j.ccell.2022.08.014

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      Rabbit polyclonal anti-LAMP-1

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    A common genetic variant in ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics
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    A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics
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    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
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  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytes in stress accumulate lipid droplets
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  113. Jan 2021
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    OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy
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  115. Nov 2020
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  117. Oct 2020
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  119. Sep 2020
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    Synaptotagmin‐7 enhances calcium‐sensing of chromaffin cell granules and slows discharge of granule cargos
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction
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  123. www.cell.com www.cell.com
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    Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
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  128. www.cell.com www.cell.com
    Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation
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  129. journals.physiology.org journals.physiology.org
    A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics | American Journal of Physiology-Cell Physiology
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  130. Jan 2020
  131. www.sciencedirect.com www.sciencedirect.com
    Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity
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  133. www.sciencedirect.com www.sciencedirect.com
    Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles
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  134. www.jneurosci.org www.jneurosci.org
    PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux
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      DOI: 10.1523/JNEUROSCI.2942-18.2019

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  135. www.sciencedirect.com www.sciencedirect.com
    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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  138. Nov 2018
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    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway
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  142. www.jneurosci.org www.jneurosci.org
    Mutant huntingtin is secreted via a late endosomal/lysosomal unconventional secretory pathway
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    Phospho-Regulation of Soma-to-Axon Transcytosis of Neurotrophin Receptors
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    Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
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    A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection
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