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    Targeted phagocytosis of TNF-α by CAR macrophages restores immune homeostasis in arthritis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13549430/
  3. Jun 2026
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    Mume Flos ameliorates MASLD-associated cognitive impairment by attenuating IL-17/NF-κB-mediated metabolic neuroinflammation
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    link.springer.com/article/10.1007/s11011-026-01883-z
  5. May 2026
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    Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4+ T cells in a mouse model of multiple sclerosis
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    MCC950 suppresses NLRP3-dependent neuroinflammation and ameliorates cognitive decline in a rat model of cerebral small vessel disease
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    Genistein-3’-sodium sulfonate improves neuroinflammation, blood-brain barrier function, and microglial activation after chronic cerebral hypoperfusion by regulating TGR5
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  9. Mar 2026
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    5-hydroxytryptamine 2B Receptor Antagonism Restores ATP and Reduces Tubulointerstitial Fibrosis in the Renal Cortices of Aged Mice
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    NPC2 suppresses osteolytic metastasis in lung adenocarcinoma via the AKT/mTOR pathway and tumor-osteoclast crosstalk
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  12. Jan 2026
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    Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease
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    A Novel TLR4 Inhibitor DB03476 Rescued Renal Inflammation in Acute Kidney Injury Model
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    CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract
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    B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity
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  17. Dec 2025
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    Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice
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    Protective effects of alkaloidal fraction of Elaeocarpus angustifolius Blume against AlCl₃-evoked neurotoxicity: insights from an in vivo model of Alzheimer’s disease
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  21. Nov 2025
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    Liquiritigenin attenuates alcohol-induced liver inflammation by regulating the SphK1/S1P/SPNS2 signaling pathway
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  23. Sep 2025
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    Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization
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  25. Aug 2025
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    Nrf2/Nlrp3 Signaling in Aging BMSCs: Traf6 Intervention as a Novel Approach to Osteoporosis Treatment
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  27. Jun 2025
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    Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
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    Mitochondrial Transplantation: Adaptive Bio-enhancement
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  35. Jan 2025
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    Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients
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    Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling
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  38. Jul 2024
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    Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology
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    Therapeutic targeting of immunometabolism reveals a critical reliance on hexokinase 2 dosage for microglial activation and Alzheimer’s progression
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  41. May 2024
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    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
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  43. Dec 2023
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    NSC48160 targets AMPKα to ameliorate nonalcoholic steatohepatitis by inhibiting lipogenesis and mitochondrial oxidative stress
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  45. Oct 2023
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    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
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  47. Jul 2023
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    Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing
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  49. Jun 2023
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  51. May 2023
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  53. Jan 2023
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    SYTL5 promotes papillary thyroid carcinoma progression by enhancing activation of the NF-κB signaling pathway
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  55. Dec 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Morusin Protected Ruminal Epithelial Cells against Lipopolysaccharide-Induced Inflammation through Inhibiting EGFR-AKT/NF-κB Signaling and Improving Barrier Functions
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  57. Sep 2022
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    Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages
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  59. Aug 2022
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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  61. Jul 2022
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    MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus
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  63. Aug 2021
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  65. Jul 2021
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibiting Brd4 alleviated PTSD-like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats
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  67. Jun 2021
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    Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy
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  69. Apr 2021
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    Optogenetic activation of spinal microglia triggers chronic pain in mice
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  71. Sep 2020
  72. www.frontiersin.org www.frontiersin.org
    Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose
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  73. Nov 2018
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse
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    Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
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    Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity
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  78. Nov 2017
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma
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