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Astrocytic glucose metabolism regulates the survival of newborn hippocampal neurons in the adult brain

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1. scibot 07 Apr 2026
  
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  DOI: 10.1016/j.neuron.2026.03.021
  
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sciencedirect.com/science/article/pii/S0896627326002126
Mar 2026
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Generation of cynomolgus embryonic stem cell line (KP-CmESC-C1) from blastocysts produced by intracellular sperm injection

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.scr.2026.103970
  
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sciencedirect.com/science/article/pii/S1873506126000668
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Species-specific chromatin architecture and neurogenesis mediated by a human enhancer

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.02.009
  
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sciencedirect.com/science/article/pii/S1934590926000792
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Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

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1. scibot 18 Mar 2026
  
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  DOI: 10.1016/j.celrep.2025.116794
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12974579/
Feb 2026
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Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.117027
  
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sciencedirect.com/science/article/pii/S2211124726001051
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Ttc21b is required for proper forebrain neural progenitor proliferation

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1. scibot 21 Feb 2026
  
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  DOI: 10.1242/dmm.052392
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12919951/
Jan 2026
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Cerebral organoids expressing mutant actin genes reveal cellular mechanism underlying microcephaly

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1. scibot 31 Jan 2026
  
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  DOI: 10.1038/s44319-025-00647-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12852704/
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Intra-pol proviral open region of HTLV-1 controls the transcription from both long terminal repeats

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1. scibot 16 Jan 2026
  
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  DOI: 10.1186/s12977-025-00671-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12797934/
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Aberrant calcium signaling and neuronal activity in the L271H CACNA1D (Cav1.3) iPSC model of neurodevelopmental disease

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1. scibot 13 Jan 2026
  
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  DOI: 10.1038/s41380-025-03429-8
  
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nature.com/articles/s41380-025-03429-8
Dec 2025
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PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate

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1. scibot 02 Dec 2025
  
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  DOI: 10.1038/s41467-025-65756-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12663461/
Sep 2025
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Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.009
  
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sciencedirect.com/science/article/pii/S1534580725005295
Jul 2025
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Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.016
  
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sciencedirect.com/science/article/pii/S089662732500474X
May 2025
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Impact of ATF6 deletion on the embryonic brain development

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1. scibot 20 May 2025
  
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  DOI: 10.1016/j.isci.2025.112569
  
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sciencedirect.com/science/article/pii/S2589004225008302
Mar 2025
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Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia

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1. scibot 28 Mar 2025
  
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  DOI: 10.1083/jcb.202310157
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11450323/
Feb 2025
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Analysis of β-Catenin Signalling Activity Suggests Differential Regulation of Ontogenetically Distinct Dentate Granule Neuron Populations

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1. scibot 20 Feb 2025
  
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  DOI: 10.1002/jdn.70009
  
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onlinelibrary.wiley.com/doi/10.1002/jdn.70009
Jan 2025
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Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex

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1. scibot 25 Jan 2025
  
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  DOI: 10.1038/s44318-024-00327-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11729872/
Dec 2024
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Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

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1. scibot 22 Dec 2024
  
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  DOI: 10.3389/fnmol.2024.1505434
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11646887/
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Satb1 regulates Contactin 5 to pattern dendrites of a mammalian retinal ganglion cell

1
1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.neuron.2017.07.019
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5575751/
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EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.014
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00696-8
Oct 2024
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Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

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1. scibot 04 Oct 2024
  
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  DOI: 10.1038/s41380-024-02761-9
  
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nature.com/articles/s41380-024-02761-9
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Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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1. scibot 02 Oct 2024
  
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  DOI: 10.4103/NRR.NRR-D-23-01446
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11433904/
Aug 2024
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Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114582
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00911-2
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S‐phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23801
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23801/full
Jul 2024
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Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114525
  
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cell.com/cell-reports/abstract/S2211-1247(24)00854-4
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Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.015
  
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sciencedirect.com/science/article/pii/S1934590924002509
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Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101647
  
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sciencedirect.com/science/article/pii/S2666379124003616
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DCX knockout ferret reveals a neurogenic mechanism in cortical development

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114508
  
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sciencedirect.com/science/article/pii/S2211124724008374
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Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

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1. scibot 17 Jul 2024
  
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  DOI: 10.4103/NRR.NRR-D-23-00928
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11246146/
May 2024
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The Neurog2-Tbr2 axis forms a continuous transition to the neurogenic gene expression state in neural stem cells

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.019
  
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sciencedirect.com/science/article/pii/S1534580724002946
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Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.neuron.2024.04.006
  
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sciencedirect.com/science/article/pii/S0896627324002447
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Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.cels.2024.04.001
  
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sciencedirect.com/science/article/pii/S2405471224001169
Apr 2024
www.embopress.org www.embopress.org

The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex

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1. scibot 25 Apr 2024
  
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  DOI: 10.1038/s44318-024-00068-7
  
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2. scibot 19 Apr 2024
  
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  DOI: 10.1038/s44318-024-00068-7
  
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embopress.org/doi/full/10.1038/s44318-024-00068-7
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The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex

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1. scibot 25 Apr 2024
  
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  DOI: 10.1038/s44318-024-00068-7
  
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embopress.org/doi/10.1038/s44318-024-00068-7
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SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.025
  
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sciencedirect.com/science/article/pii/S153458072400193X
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Protocol for generating mouse morula-like cells resembling 8- to 16-cell stage embryo cells

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1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.xpro.2024.102934
  
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  DOI: 10.1016/j.xpro.2024.102934
  
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sciencedirect.com/science/article/pii/S2666166724000996
Mar 2024
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Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders

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Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression

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Feb 2024
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ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells

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Sirt6 regulates proliferation of neural precursor cells and cortical neurogenesis in mice

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Jan 2024
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Notch Signaling Plays a Dual Role in Regulating the Neuron-to-Oligodendrocyte Switch in the Developing Dorsal Forebrain

2
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Human fetal brain self-organizes into long-term expanding organoids

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Dec 2023
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FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration

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Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture

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Lysosomal dynamics regulate mammalian cortical neurogenesis

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Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb

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Oct 2023
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In vitro generation of mouse morula-like cells

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Embryo model completes gastrulation to neurulation and organogenesis

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Transgene directed induction of a stem cell-derived human embryo model

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PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model

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Aug 2023
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Eomes restricts Brachyury functions at the onset of mouse gastrulation

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Jul 2023
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FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

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TIMP3 promotes the maintenance of neural stem-progenitor cells in the mouse subventricular zone

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Protocol for generating in vitro glioma models using human-induced pluripotent- or embryonic-stem-cell-derived cerebral organoids

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Jun 2023
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Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation

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Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice

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Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis

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May 2023
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Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

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Neuronal progenitors of the dentate gyrus express the SARS-CoV-2 cell receptor during migration in the developing human hippocampus

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Presenilin enhancer2 is critical for the transition of apical progenitors to neurons but not basal progenitors in the developing hippocampus

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Apr 2023
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Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells

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Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex

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Mar 2023
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Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage

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Generation of an induced pluripotent stem cell line carrying a biallelic deletion (SCTCi019-A) in GCDH using CRISPR/Cas9

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Feb 2023
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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model

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Protocol to generate induced trophoblast stem cells from embryonic stem cells in mice

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Jan 2023
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In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis

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Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

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Laminar dynamics of deep projection neurons and mode of subplate formation are hallmarks of histogenetic subdivisions of the human cingulate cortex before onset of arealization

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Dec 2022
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Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis

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A critical period of translational control during brain development at codon resolution

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Nov 2022
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Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features

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CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors

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miR-409-3p represses Cited2 to refine neocortical layer V projection neuron identity

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Sep 2022
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Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development

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¬Post-Gastrulation Synthetic Embryos Generated Ex Utero from Mouse Naïve ESCs

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Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids

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Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development

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Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition

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Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions

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Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation

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Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero

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Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex

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Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model

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The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling

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Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm

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Rif1 and Hmgn3 regulate the conversion of murine trophoblast stem cells

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Feb 2022
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Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L

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SoxD genes are required for adult neural stem cell activation

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Methyl donor supplementation prevents a folate deficiency-induced depression-like state and neuronal immaturity of the dentate gyrus in mice

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Rapid generation of murine haploid-induced trophoblast stem cells via a Tet-on system

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Oct 2021
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Greater Number of Microglia in Telencephalic Proliferative Zones of Human and Non-Human Primate Compared to Other Vertebrate Species

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Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

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Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development

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Visualization of individual cell division history in complex tissues using iCOUNT

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Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions

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The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus

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Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding

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Characterization of Tbr2-expressing retinal ganglion cells

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Untitled document

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Untitled document

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Untitled document

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Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations

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A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis

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A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

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Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells

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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

1
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The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number

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Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells

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Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts

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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling

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The expression of tubb2b undergoes a developmental transition in murine cortical neurons

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BMPR-2 gates activity-dependent stabilization of primary dendrites during mitral cell remodeling

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Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior

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Generation and validation of APOE knockout human iPSC-derived cerebral organoids

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DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction

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Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification

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The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis

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Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

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Generation of human pluripotent stem cell-derived fused organoids with oligodendroglia and myelin

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Heterogeneity of glial progenitor cells during the neurogenesis-to-gliogenesis switch in the developing human cerebral cortex

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A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain

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Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex

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Olig3 regulates early cerebellar development

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Dentate gyrus development requires a cortical hem-derived astrocytic scaffold

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Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro

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Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions

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Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency

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ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence

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Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality

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LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

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A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

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Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development

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Intrauterine Pressures Adjusted by Reichert’s Membrane Are Crucial for Early Mouse Morphogenesis

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β‐catenin signaling modulates the tempo of dendritic growth of adult‐born hippocampal neurons

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Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex

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Smad Anchor for Receptor Activation (SARA) nuclear localization during development identifies layers V and VI of the neocortex

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NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification

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FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

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Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity

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Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways

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Mitf links neuronal activity and long-term homeostatic intrinsic plasticity

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A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System

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Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

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Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons

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Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

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Expression of transcription factors divides retinal ganglion cells into distinct classes

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Regional differences in mitral cell development in mouse olfactory bulb

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SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export

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N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

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Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded

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Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development

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Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid

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Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis

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The PROK2/PROKR2 Signaling Pathway is Required for the Migration of Most Olfactory Bulb Interneurons

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Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex

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FGF signaling directs the cell fate switch from neurons to astrocytes in the developing mouse cerebral cortex

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Untitled document

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Untitled document

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Untitled document

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells

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Derivation of Mouse Haploid Trophoblast Stem Cells

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Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation

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ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development

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Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

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Human Huntington’s Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation

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Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory

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E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors’ activity in an E-box-dependent manner

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Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool

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