115 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
    1
    1. scibot 30 May 2024
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2024.114294

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    sciencedirect.com/science/article/pii/S2211124724006223
  3. www.sciencedirect.com www.sciencedirect.com
    Autophagy preferentially degrades non-fibrillar polyQ aggregates
    1
    1. scibot 17 May 2024
      RRID:AB_796155

      DOI: 10.1016/j.molcel.2024.04.018

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    sciencedirect.com/science/article/pii/S1097276524003836
  4. Apr 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Variant-specific effects of GBA1 mutations on dopaminergic neuron proteostasis
    1
    1. scibot 25 Apr 2024
      RRID:AB_796155

      DOI: 10.1111/jnc.16114

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16114
  6. www.sciencedirect.com www.sciencedirect.com
    The clinical antiprotozoal drug nitazoxanide and its metabolite tizoxanide extend Caenorhabditis elegans lifespan and healthspan
    1
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.apsb.2024.03.031

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    sciencedirect.com/science/article/pii/S2211383524001242
  7. Mar 2024
  8. rupress.org rupress.org
    Rab32 family proteins regulate autophagosomal components recycling
    2
    1. scibot 21 Mar 2024
      RRID:AB_796155

      DOI: 10.1083/jcb.202306040

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    2. scibot 21 Mar 2024
      RRID:AB_796155

      DOI: 10.1083/jcb.202306040

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    rupress.org/jcb/article/223/3/e202306040/276549/Rab32-family-proteins-regulate-autophagosomal
  9. Feb 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Sorafenib extends the lifespan of C. elegans through mitochondrial uncoupling mechanism
    1
    1. scibot 15 Feb 2024
      RRID:AB_796155

      DOI: 10.1016/j.freeradbiomed.2024.02.008

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    sciencedirect.com/science/article/pii/S0891584924000881
  11. www.sciencedirect.com www.sciencedirect.com
    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
    3
    1. scibot 13 Feb 2024
      AB_796155

      DOI: 10.1016/j.celrep.2024.113760

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    2. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113760

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    3. scibot 13 Feb 2024
      AB_796155

      DOI: 10.1016/j.celrep.2024.113760

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    sciencedirect.com/science/article/pii/S2211124724000883
  12. www.sciencedirect.com www.sciencedirect.com
    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
    2
    1. scibot 02 Feb 2024
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2024.113707

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    2. scibot 02 Feb 2024
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2024.113707

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    sciencedirect.com/science/article/pii/S2211124724000354
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival
    1
    1. scibot 19 Jan 2024
      AB_796155

      DOI: 10.1016/j.isci.2024.108795

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    sciencedirect.com/science/article/pii/S2589004224000166
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
    1
    1. scibot 05 Jan 2024
      RRID:AB_796155

      DOI: 10.1083/jcb.202211025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10316704/
  16. www.jneurosci.org www.jneurosci.org
    Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis
    1
    1. scibot 02 Jan 2024
      RRID:AB_796155

      DOI: 10.1523/JNEUROSCI.1318-23.2023

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    jneurosci.org/content/43/50/8812
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
    1
    1. scibot 19 Dec 2023
      RRID:AB_796155

      DOI: 10.1016/j.devcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1534580723006214
  19. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
    1
    1. scibot 16 Dec 2023
      RRID:AB_796155

      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  20. Nov 2023
  21. www.embopress.org www.embopress.org
    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
    1
    1. scibot 03 Nov 2023
      RRID:AB_796155

      DOI: 10.15252/embr.202357500

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    embopress.org/doi/10.15252/embr.202357500
  22. Oct 2023
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bilirubin impacts microglial autophagy via the Akt–mTOR signaling pathway
    1
    1. scibot 27 Oct 2023
      RRID:AB_796155

      DOI: 10.1111/jnc.15984

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15984
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
    1
    1. scibot 12 Oct 2023
      RRID:AB_796155

      DOI: 10.1083/jcb.202303078

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561555/
  25. Aug 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation
    1
    1. scibot 25 Aug 2023
      AB_796155

      DOI: 10.1016/j.celrep.2023.113032

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    sciencedirect.com/science/article/pii/S2211124723010434
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Staphylococcus aureus phagocytosis is affected by senescence
    1
    1. scibot 19 Aug 2023
      RRID:AB_796155

      DOI: 10.3389/fragi.2023.1198241

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    ncbi.nlm.nih.gov/pmc/articles/PMC10423838/
  28. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of Raptor transduces glucose signals to mTORC1
    1
    1. scibot 04 Aug 2023
      RRID:AB_796155

      DOI: 10.1016/j.molcel.2023.07.011

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    sciencedirect.com/science/article/abs/pii/S1097276523005269
  29. Jul 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
    1
    1. scibot 21 Jul 2023
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2023.112817

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    sciencedirect.com/science/article/pii/S2211124723008288
  31. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
    2
    1. scibot 21 Jul 2023
      RRID:AB_796155

      DOI: 10.1111/bph.16190

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    2. scibot 21 Jul 2023
      RRID:AB_796155

      DOI: 10.1111/bph.16190

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    52.53.155.43/01e7f498781407a431fc8d9b3b9cdd8be1437af6/British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
  32. www.sciencedirect.com www.sciencedirect.com
    Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity
    1
    1. scibot 13 Jul 2023
      AB_796155

      DOI: 10.1016/j.immuni.2023.06.013

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    sciencedirect.com/science/article/abs/pii/S1074761323002716
  33. Jun 2023
  34. www.sciencedirect.com www.sciencedirect.com
    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
    1
    1. scibot 29 Jun 2023
      AB_796155

      DOI: 10.1016/j.celrep.2023.112701

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    sciencedirect.com/science/article/pii/S221112472300712X
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
    1
    1. scibot 27 Jun 2023
      RRID:AB_796155

      DOI: 10.1080/15548627.2023.2169309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10283425/
  36. May 2023
  37. www.embopress.org www.embopress.org
    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy
    1
    1. scibot 25 May 2023
      RRID:AB_796155

      DOI: 10.15252/emmm.202216951

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    embopress.org/doi/full/10.15252/emmm.202216951
  38. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
    1
    1. scibot 18 May 2023
      RRID:AB_796155

      DOI: 10.1016/j.isci.2023.106770

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    sciencedirect.com/science/article/pii/S2589004223008477
  39. Apr 2023
  40. www.biorxiv.org www.biorxiv.org
    Optineurin provides a mitophagy contact site for TBK1 activation
    1
    1. scibot 12 Apr 2023
      RRID:AB_796155

      DOI: 10.1101/2023.02.24.529790

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    biorxiv.org/content/10.1101/2023.02.24.529790v1
  41. www.nature.com www.nature.com
    Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model
    1
    1. scibot 11 Apr 2023
      RRID:AB_796155

      DOI: 10.1038/s42003-023-04770-w

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    nature.com/articles/s42003-023-04770-w
  42. Mar 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Monitoring autophagic flux in vivo revealed its physiological response and significance of heterogeneity in pancreatic beta cells
    1
    1. scibot 28 Mar 2023
      RRID:AB_796155

      DOI: 10.1016/j.chembiol.2023.03.001

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    sciencedirect.com/science/article/pii/S2451945623000600
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
    1
    1. scibot 23 Mar 2023
      RRID:AB_796155

      DOI: 10.3389/fphar.2023.1094584

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    ncbi.nlm.nih.gov/pmc/articles/PMC10027750/
  45. www.sciencedirect.com www.sciencedirect.com
    Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson’s disease
    1
    1. scibot 16 Mar 2023
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2023.112231

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    sciencedirect.com/science/article/pii/S2211124723002425
  46. www.sciencedirect.com www.sciencedirect.com
    Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
    1
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      DOI: 10.1016/j.celrep.2023.112180

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    sciencedirect.com/science/article/pii/S2211124723001912
  47. Feb 2023
  48. www.mdpi.com www.mdpi.com
    The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis
    1
    1. scibot 04 Feb 2023
      RRID:AB_796155

      DOI: 10.3390/ijms24032749

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    mdpi.com/1422-0067/24/3/2749
  49. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
    1
    1. scibot 04 Feb 2023
      RRID:AB_796155

      DOI: 10.1038/s41467-023-36058-2

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    nature.com/articles/s41467-023-36058-2
  50. Jan 2023
  51. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
    1
    1. scibot 14 Jan 2023
      AB_796155

      DOI: 10.1111/bph.15986

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15986
  52. www.sciencedirect.com www.sciencedirect.com
    The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation
    1
    1. scibot 02 Jan 2023
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2022.111906

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    sciencedirect.com/science/article/pii/S2211124722018058
  53. Dec 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
    1
    1. scibot 24 Dec 2022
      RRID:AB_796155

      DOI: 10.1016/j.celrep.2022.111850

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    sciencedirect.com/science/article/pii/S2211124722017429
  55. Nov 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication
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    The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debris
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  58. Oct 2022
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    Autophagy activation attenuates the circadian clock oscillators in U2OS cells via the ATG5 pathway
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    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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  61. Aug 2022
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    Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
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  63. Jul 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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    Acetylation of p62 regulates base excision repair through interaction with APE1
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  66. May 2022
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    Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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  69. Apr 2022
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    Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques
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    Recycling of autophagosomal components from autolysosomes by the recycler complex
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  72. Mar 2022
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model
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    Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy
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    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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  76. Feb 2022
  77. www.tandfonline.com www.tandfonline.com
    The endoplasmic reticulum stress-mediated unfolded protein response protects against infection of goat endometrial epithelial cells by Trueperella pyogenes via autophagy
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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  79. Sep 2021
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
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    onlinelibrary.wiley.com/doi/10.1111/jcmm.16910
  81. Aug 2021
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    Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
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  88. Jul 2021
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    Research Paper - By Targeting Atg7 MicroRNA-143 Mediates Oxidative Stress-Induced Autophagy of c-Kit+ Mouse Cardiac Progenitor Cells
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      DOI: 10.1016/j.ebiom.2018.05.021

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    Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
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    Delivering progranulin to neuronal lysosomes protects against excitotoxicity
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    Neuronal VCP loss of function recapitulates FTLD-TDP pathology
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  96. Jun 2021
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    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
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    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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  99. Apr 2021
  100. www.cell.com www.cell.com
    β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells
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    cell.com/current-biology/abstract/S0960-9822(21)00146-9
  101. Mar 2021
  102. www.frontiersin.org www.frontiersin.org
    FSH Promotes Progesterone Synthesis by Enhancing Autophagy to Accelerate Lipid Droplet Degradation in Porcine Granulosa Cells
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    Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
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  104. Feb 2021
  105. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12
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  107. Dec 2020
  108. www.sciencedirect.com www.sciencedirect.com
    Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth
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  109. Nov 2020
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells
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  111. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
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  112. Sep 2020
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    Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling
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    Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
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    Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
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    Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells
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    Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma
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    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination
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  121. Jan 2020
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    Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform
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    Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
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    Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy
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    LncRNA MEG3 contributes to adenosine‐induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K‐AKT‐mTOR and beclin‐1 signaling pathway
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    Light-Activated ROS Production Induces Synaptic Autophagy
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    ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97
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  134. Nov 2018
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    Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell Specific Changes of Autophagy in a Mouse Model of Contusive Spinal Cord Injury
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    Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice
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    ZFAND1 Recruits p97 and the 26S Proteasome to Promote the Clearance of Arsenite-Induced Stress Granules
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    Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia
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    Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice
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    Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy
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  144. Nov 2017
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    DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
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    Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases
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    Bassoon Controls Presynaptic Autophagy through Atg5
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