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  1. Last 7 days
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    sciencedirect.com/science/article/pii/S2211124724004777
  3. Mar 2024
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    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
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    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724003097
  5. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
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    1. scibot 01 Mar 2024
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  6. Feb 2024
  7. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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    1. scibot 22 Feb 2024
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      DOI: 10.1101/2023.10.02.560521

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  8. Dec 2023
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    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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    1. scibot 14 Dec 2023
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    sciencedirect.com/science/article/pii/S2212877823001850
  10. Nov 2023
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    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    1. scibot 17 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723013645
  12. Oct 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
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    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.isci.2023.107956

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
  14. Sep 2023
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    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
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    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  16. Jul 2023
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    Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2
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    1. scibot 08 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.020

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    sciencedirect.com/science/article/pii/S1097276523004677
  18. Jun 2023
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    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
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    1. scibot 29 Jun 2023
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    sciencedirect.com/science/article/pii/S221112472300712X
  20. May 2023
  21. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
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    1. scibot 12 May 2023
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      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
  22. Apr 2023
  23. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    1. scibot 20 Apr 2023
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    sciencedirect.com/science/article/pii/S2211124723002206
  24. Mar 2023
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    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
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    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.immuni.2023.02.018

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    sciencedirect.com/science/article/pii/S1074761323000924
  26. Feb 2023
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    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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    1. scibot 11 Feb 2023
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    sciencedirect.com/science/article/pii/S2589004223000421
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    MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
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    sciencedirect.com/science/article/pii/S2211124723000773
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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    sciencedirect.com/science/article/pii/S2211124723000530
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
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    1. scibot 22 Jan 2023
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      DOI: 10.3389/fimmu.2022.1083119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9849354/
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    The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria
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    sciencedirect.com/science/article/pii/S2211124722017983
  33. Dec 2022
  34. link.springer.com link.springer.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
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    1. scibot 31 Dec 2022
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      DOI: 10.1186/s12885-022-10415-8

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    link.springer.com/article/10.1186/s12885-022-10415-8
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
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    1. scibot 31 Dec 2022
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      DOI: 10.3390/ijms232416162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9786043/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  37. Nov 2022
  38. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  39. 52.53.155.43 52.53.155.43
    ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α
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      DOI: 10.21203/rs.3.rs-1947659/v1

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  40. Sep 2022
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    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012566
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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      DOI: 10.1016/j.ccell.2022.08.016

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    sciencedirect.com/science/article/pii/S1535610822003804
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
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    1. scibot 02 Sep 2022
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      DOI: 10.1080/2162402X.2022.2116844

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    ncbi.nlm.nih.gov/pmc/articles/PMC9423862/
  44. Aug 2022
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    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
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    1. scibot 30 Aug 2022
      RRID:AB_10830732

      DOI: 10.1016/j.cmet.2022.08.005

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    sciencedirect.com/science/article/pii/S1550413122003485
  46. Jul 2022
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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      DOI: 10.1016/j.chembiol.2022.07.002

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    sciencedirect.com/science/article/pii/S2451945622002458
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    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  49. Apr 2022
  50. www.sciencedirect.com www.sciencedirect.com
    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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      DOI: 10.1016/j.devcel.2022.03.012

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    sciencedirect.com/science/article/pii/S1534580722002064
  51. Feb 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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      DOI: 10.1016/j.isci.2022.103859

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    sciencedirect.com/science/article/pii/S2589004222001298
  53. www.sciencedirect.com www.sciencedirect.com
    Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
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      DOI: 10.1016/j.chembiol.2022.01.002

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    sciencedirect.com/science/article/pii/S2451945622000022
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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      3294

      DOI: 10.1002/ddr.21916

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    onlinelibrary.wiley.com/doi/10.1002/ddr.21916
  55. Jan 2022
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Jan 2022
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      DOI: 10.1111/bph.15744

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15744
  57. Dec 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism
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    1. scibot 08 Dec 2021
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      DOI: 10.7554/eLife.73215

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    ncbi.nlm.nih.gov/pmc/articles/PMC8635982/
  59. Nov 2021
  60. academic.oup.com academic.oup.com
    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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      RRID:AB_823545

      DOI: 10.1210/endocr/bqab212

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    academic.oup.com/endo/article/163/1/bqab212/6382455
  61. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Differential ER Stress as a Driver of Cell Fate following Ricin Toxin Exposure
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      DOI: 10.1096/fba.2021-00005

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fba.2021-00005
  62. Oct 2021
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    Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      DOI: 10.1016/j.ccell.2019.01.006

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  114. www.sciencedirect.com www.sciencedirect.com
    Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation
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      DOI: 10.1016/j.celrep.2019.03.017

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  115. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2018.12.012

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  116. Nov 2018
  117. www.sciencedirect.com www.sciencedirect.com
    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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  118. www.sciencedirect.com www.sciencedirect.com
    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis
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  122. Nov 2017
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    The Sec61 translocon limits IRE1α signaling during the unfolded protein response
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    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
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      3294

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