96 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
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    1. scibot 19 Jul 2024
      AB_823545

      DOI: 10.1523/JNEUROSCI.1799-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10146492/
  3. Jul 2024
  4. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 12 Jul 2024
      RRID:AB_823545

      DOI: 10.1111/bph.16485

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16485
  5. Jun 2024
  6. www.sciencedirect.com www.sciencedirect.com
    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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    1. scibot 21 Jun 2024
      RRID:AB_823545

      DOI: 10.1016/j.isci.2024.110196

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    sciencedirect.com/science/article/pii/S2589004224014214
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    BPS Publications
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    1. scibot 06 Jun 2024
      RRID:AB_823545

      DOI: 10.1111/bph.16436

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16436
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
      RRID:AB_823545

      DOI: 10.1016/j.cmet.2024.04.014

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    sciencedirect.com/science/article/pii/S1550413124001347
  10. Apr 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
  12. Mar 2024
  13. www.sciencedirect.com www.sciencedirect.com
    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
    2
    1. scibot 29 Mar 2024
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2024.113981

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    2. scibot 29 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113981

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    sciencedirect.com/science/article/pii/S2211124724003097
  14. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
    1
    1. scibot 01 Mar 2024
      AB_82354594

      DOI: 10.1016/j.isci.2024.109100

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    52.53.155.43/d3d22b34dc913e3c2adad8dc51a7839208721c99/PIIS2589004224003213-html.html
  15. Feb 2024
  16. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
    1
    1. scibot 22 Feb 2024
      RRID:AB_82

      DOI: 10.1101/2023.10.02.560521

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    52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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    1. scibot 14 Dec 2023
      RRID:AB_823545

      DOI: 10.1016/j.molmet.2023.101851

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    sciencedirect.com/science/article/pii/S2212877823001850
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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    1. scibot 17 Nov 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  21. Oct 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
    1
    1. scibot 14 Oct 2023
      RRID:AB_823545

      DOI: 10.1016/j.isci.2023.107956

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
  23. Sep 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_823545

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  25. Jul 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2
    1
    1. scibot 08 Jul 2023
      RRID:AB_823545

      DOI: 10.1016/j.molcel.2023.06.020

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    sciencedirect.com/science/article/pii/S1097276523004677
  27. Jun 2023
  28. www.sciencedirect.com www.sciencedirect.com
    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
    1
    1. scibot 29 Jun 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112701

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    sciencedirect.com/science/article/pii/S221112472300712X
  29. May 2023
  30. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
    1
    1. scibot 12 May 2023
      RRID: AB_823545

      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
    1
    1. scibot 20 Apr 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  33. Mar 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
    1
    1. scibot 16 Mar 2023
      RRID:AB_823

      DOI: 10.1016/j.immuni.2023.02.018

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    sciencedirect.com/science/article/pii/S1074761323000924
  35. Feb 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
    1
    1. scibot 11 Feb 2023
      RRID:AB_823545

      DOI: 10.1016/j.isci.2023.105965

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    sciencedirect.com/science/article/pii/S2589004223000421
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    MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
    1
    1. scibot 09 Feb 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112066

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    sciencedirect.com/science/article/pii/S2211124723000773
  38. Jan 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
    1
    1. scibot 26 Jan 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112042

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    sciencedirect.com/science/article/pii/S2211124723000530
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
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    1. scibot 22 Jan 2023
      RRID:AB_823545

      DOI: 10.3389/fimmu.2022.1083119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9849354/
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    The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria
    1
    1. scibot 02 Jan 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111899

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    sciencedirect.com/science/article/pii/S2211124722017983
  42. Dec 2022
  43. link.springer.com link.springer.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
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    1. scibot 31 Dec 2022
      RRID:AB_823545

      DOI: 10.1186/s12885-022-10415-8

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    link.springer.com/article/10.1186/s12885-022-10415-8
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
    1
    1. scibot 31 Dec 2022
      RRID:AB_823545

      DOI: 10.3390/ijms232416162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9786043/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
    1
    1. scibot 08 Dec 2022
      RRID:AB_823545

      DOI: 10.1016/j.isci.2022.105626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  46. Nov 2022
  47. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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    1. scibot 10 Nov 2022
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  48. 52.53.155.43 52.53.155.43
    ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α
    1
    1. scibot 03 Nov 2022
      RRID:AB_823545

      DOI: 10.21203/rs.3.rs-1947659/v1

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    52.53.155.43/ee9544f92d24a784e439b5f8ccd0815fd1dd27bc/f0a3133f-5e3c-40fc-b375-09b76f1fe1f4-html.html
  49. Sep 2022
  50. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
    1
    1. scibot 29 Sep 2022
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111415

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    sciencedirect.com/science/article/pii/S2211124722012566
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    1
    1. scibot 24 Sep 2022
      RRID:AB_823545

      DOI: 10.1016/j.ccell.2022.08.016

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    sciencedirect.com/science/article/pii/S1535610822003804
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
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    1. scibot 02 Sep 2022
      RRID:AB_823545

      DOI: 10.1080/2162402X.2022.2116844

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    ncbi.nlm.nih.gov/pmc/articles/PMC9423862/
  53. Aug 2022
  54. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
    1
    1. scibot 30 Aug 2022
      RRID:AB_10830732

      DOI: 10.1016/j.cmet.2022.08.005

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    sciencedirect.com/science/article/pii/S1550413122003485
  55. Jul 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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      RRID:AB_823545

      DOI: 10.1016/j.chembiol.2022.07.002

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    sciencedirect.com/science/article/pii/S2451945622002458
  57. www.sciencedirect.com www.sciencedirect.com
    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  58. Apr 2022
  59. www.sciencedirect.com www.sciencedirect.com
    VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites
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    1. scibot 14 Apr 2022
      RRID:AB_823545

      DOI: 10.1016/j.devcel.2022.03.012

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    sciencedirect.com/science/article/pii/S1534580722002064
  60. Feb 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
    1
    1. scibot 13 Feb 2022
      RRID:AB_823545

      DOI: 10.1016/j.isci.2022.103859

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    sciencedirect.com/science/article/pii/S2589004222001298
  62. www.sciencedirect.com www.sciencedirect.com
    Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
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    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.chembiol.2022.01.002

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      DOI: 10.1016/j.chembiol.2022.01.002

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  66. Dec 2021
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  68. Nov 2021
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    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells
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  101. Sep 2020
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    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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  117. academic.oup.com academic.oup.com
    Acute Deletion of METTL14 in β-cells of adult mice results in glucose intolerance
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  118. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2019.03.018

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    Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain
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      DOI: 10.1016/j.cellsig.2016.08.012

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation
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      DOI: 10.1016/j.celrep.2019.03.017

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  125. Nov 2018
  126. www.sciencedirect.com www.sciencedirect.com
    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis
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  131. Nov 2017
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Sec61 translocon limits IRE1α signaling during the unfolded protein response
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    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
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      3294

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