101 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders
    1
    1. scibot 25 Sep 2024
      AB_823545

      DOI: 10.1016/j.cmet.2024.08.009

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    sciencedirect.com/science/article/pii/S1550413124003619
  3. Aug 2024
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    E3 Ubiquitin Ligase Nedd4-2 Exerts Neuroprotective Effects During Endoplasmic Reticulum Stress
    1
    1. scibot 02 Aug 2024
      RRID: AB_823545

      DOI: 10.1111/jnc.15567

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15567
  5. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
    1
    1. scibot 02 Aug 2024
      3294

      DOI: 10.1186/s13578-021-00640-2

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    cellandbioscience.biomedcentral.com/article/10.1186/s13578-021-00640-2
  6. www.mdpi.com www.mdpi.com
    Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent Mice
    1
    1. scibot 02 Aug 2024
      IRE-1α

      DOI: 10.3390/cells10050996

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    mdpi.com/2073-4409/10/5/996/htm
  7. www.molbiolcell.org www.molbiolcell.org
    Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress | Molecular Biology of the Cell
    1
    1. scibot 02 Aug 2024
      RRID:AB_823545

      DOI: 10.1091/mbc.E17-10-0594

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    molbiolcell.org/doi/abs/10.1091/mbc.E17-10-0594
  8. Jul 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
    1
    1. scibot 19 Jul 2024
      AB_823545

      DOI: 10.1523/JNEUROSCI.1799-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10146492/
  10. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 12 Jul 2024
      RRID:AB_823545

      DOI: 10.1111/bph.16485

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16485
  11. Jun 2024
  12. www.sciencedirect.com www.sciencedirect.com
    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
    1
    1. scibot 21 Jun 2024
      RRID:AB_823545

      DOI: 10.1016/j.isci.2024.110196

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    sciencedirect.com/science/article/pii/S2589004224014214
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 06 Jun 2024
      RRID:AB_823545

      DOI: 10.1111/bph.16436

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16436
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
      RRID:AB_823545

      DOI: 10.1016/j.cmet.2024.04.014

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    sciencedirect.com/science/article/pii/S1550413124001347
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
    1
    1. scibot 30 Apr 2024
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2024.114149

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    sciencedirect.com/science/article/pii/S2211124724004777
  18. Mar 2024
  19. www.sciencedirect.com www.sciencedirect.com
    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
    2
    1. scibot 29 Mar 2024
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2024.113981

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    2. scibot 29 Mar 2024
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2024.113981

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    sciencedirect.com/science/article/pii/S2211124724003097
  20. 52.53.155.43 52.53.155.43
    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
    1
    1. scibot 01 Mar 2024
      AB_82354594

      DOI: 10.1016/j.isci.2024.109100

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    52.53.155.43/d3d22b34dc913e3c2adad8dc51a7839208721c99/PIIS2589004224003213-html.html
  21. Feb 2024
  22. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
    1
    1. scibot 22 Feb 2024
      RRID:AB_82

      DOI: 10.1101/2023.10.02.560521

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    52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
    1
    1. scibot 14 Dec 2023
      RRID:AB_823545

      DOI: 10.1016/j.molmet.2023.101851

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    sciencedirect.com/science/article/pii/S2212877823001850
  25. Nov 2023
  26. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  27. Oct 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
    1
    1. scibot 14 Oct 2023
      RRID:AB_823545

      DOI: 10.1016/j.isci.2023.107956

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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
  29. Sep 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_823545

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  31. Jul 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2
    1
    1. scibot 08 Jul 2023
      RRID:AB_823545

      DOI: 10.1016/j.molcel.2023.06.020

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    sciencedirect.com/science/article/pii/S1097276523004677
  33. Jun 2023
  34. www.sciencedirect.com www.sciencedirect.com
    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
    1
    1. scibot 29 Jun 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112701

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    sciencedirect.com/science/article/pii/S221112472300712X
  35. May 2023
  36. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
    1
    1. scibot 12 May 2023
      RRID: AB_823545

      DOI: 10.1210/endocr/bqad035

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    academic.oup.com/endo/article/164/4/bqad035/7056674
  37. Apr 2023
  38. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    1. scibot 20 Apr 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  39. Mar 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
    1
    1. scibot 16 Mar 2023
      RRID:AB_823

      DOI: 10.1016/j.immuni.2023.02.018

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    sciencedirect.com/science/article/pii/S1074761323000924
  41. Feb 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
    1
    1. scibot 11 Feb 2023
      RRID:AB_823545

      DOI: 10.1016/j.isci.2023.105965

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    sciencedirect.com/science/article/pii/S2589004223000421
  43. www.sciencedirect.com www.sciencedirect.com
    MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
    1
    1. scibot 09 Feb 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112066

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    sciencedirect.com/science/article/pii/S2211124723000773
  44. Jan 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
    1
    1. scibot 26 Jan 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2023.112042

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    sciencedirect.com/science/article/pii/S2211124723000530
  46. www.frontiersin.org www.frontiersin.org
    A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
    1
    1. scibot 22 Jan 2023
      RRID:AB_823545

      DOI: 10.3389/fimmu.2022.1083119

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    frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1083119/full
  47. www.sciencedirect.com www.sciencedirect.com
    The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria
    1
    1. scibot 02 Jan 2023
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111899

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    sciencedirect.com/science/article/pii/S2211124722017983
  48. Dec 2022
  49. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
    1
    1. scibot 31 Dec 2022
      RRID:AB_823545

      DOI: 10.1186/s12885-022-10415-8

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    bmccancer.biomedcentral.com/articles/10.1186/s12885-022-10415-8
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
    1
    1. scibot 31 Dec 2022
      RRID:AB_823545

      DOI: 10.3390/ijms232416162

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    ncbi.nlm.nih.gov/pmc/articles/PMC9786043/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
    1
    1. scibot 08 Dec 2022
      RRID:AB_823545

      DOI: 10.1016/j.isci.2022.105626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  52. Nov 2022
  53. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
    1
    1. scibot 10 Nov 2022
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  54. 52.53.155.43 52.53.155.43
    ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α
    1
    1. scibot 03 Nov 2022
      RRID:AB_823545

      DOI: 10.21203/rs.3.rs-1947659/v1

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    52.53.155.43/ee9544f92d24a784e439b5f8ccd0815fd1dd27bc/f0a3133f-5e3c-40fc-b375-09b76f1fe1f4-html.html
  55. Sep 2022
  56. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    1. scibot 29 Sep 2022
      RRID:AB_823545

      DOI: 10.1016/j.celrep.2022.111415

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    sciencedirect.com/science/article/pii/S2211124722012566
  57. www.sciencedirect.com www.sciencedirect.com
    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    1
    1. scibot 24 Sep 2022
      RRID:AB_823545

      DOI: 10.1016/j.ccell.2022.08.016

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    sciencedirect.com/science/article/pii/S1535610822003804
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response
    1
    1. scibot 02 Sep 2022
      RRID:AB_823545

      DOI: 10.1080/2162402X.2022.2116844

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    ncbi.nlm.nih.gov/pmc/articles/PMC9423862/
  59. Aug 2022
  60. www.sciencedirect.com www.sciencedirect.com
    PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
    1
    1. scibot 30 Aug 2022
      RRID:AB_10830732

      DOI: 10.1016/j.cmet.2022.08.005

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    sciencedirect.com/science/article/pii/S1550413122003485
  61. Jul 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
    1
    1. scibot 30 Jul 2022
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    Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
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  72. Dec 2021
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  74. Nov 2021
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  77. Oct 2021
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    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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  87. Jul 2021
  88. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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      IRE1α CD (rabbit monoclonal

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    Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus
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  96. May 2021
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  101. Mar 2021
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    TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells
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  103. Feb 2021
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  107. Sep 2020
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      rabbit anti-IRE1α

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    The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling
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    TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells | American Journal of Physiology-Lung Cellular and Molecular Physiology
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  117. Jan 2020
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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  119. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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    Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
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  122. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  123. academic.oup.com academic.oup.com
    Acute Deletion of METTL14 in β-cells of adult mice results in glucose intolerance
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    Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
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    Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation
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  131. Nov 2018
  132. www.sciencedirect.com www.sciencedirect.com
    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
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    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis
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    sciencedirect.com/science/article/pii/S0960982218303038
  137. Nov 2017
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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    Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Sec61 translocon limits IRE1α signaling during the unfolded protein response
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    Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
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      3294

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