61 Matching Annotations
  1. Last 7 days
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    The natural coumarin 7-methoxy-8-isopentenyloxycoumarin alleviates LPS-induced inflammation by suppressing NF-κB and the MAPK/AP-1 pathways and accelerating COX-2 proteasomal degradation
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    sciencedirect.com/science/article/pii/S001429992600748X
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Noncanonical IRF3 function mediates STING-dependent pro-inflammatory cytokine production in macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13260819/
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    Mycobacterium tuberculosis subverts macrophage-mediated defense through exploitation of the Zn transporter ZIP8
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    sciencedirect.com/science/article/pii/S2589004226016512
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    Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells
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    sciencedirect.com/science/article/pii/S2589004226014069
  7. May 2026
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    Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02340-z
  9. Feb 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Raspberry Polyphenols Target Molecular Pathways of Heart Failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862629/
  11. Jan 2026
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    Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome
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    sciencedirect.com/science/article/pii/S2666379125006044
  13. Nov 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prolyl endopeptidase is a multifunctional host factor required for FMDV infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12630515/
  15. Oct 2025
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    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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    sciencedirect.com/science/article/pii/S1097276525008226
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protective Effect of Taxifolin Against Monochloroacetic Acid-Induced Skin Damage via Inhibition of the cGAS/STING/NF-κB Pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202502583
  18. Jul 2025
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    The immune response against cancer is modulated by stromal cell fibronectin
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    sciencedirect.com/science/article/pii/S1476558625000764
  20. Jun 2025
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    7,4′-dimethoxy-3-hydroxyflavone, a protease-activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70105
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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    sciencedirect.com/science/article/pii/S2211124725006102
  23. Feb 2025
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    ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
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    sciencedirect.com/science/article/pii/S0092867425000960
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    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk
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    sciencedirect.com/science/article/pii/S1550413124004935
  26. Sep 2024
  27. academic.oup.com academic.oup.com
    Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae596/7745547
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    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387596/
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    sciencedirect.com/science/article/pii/S2666379124004397
  30. Jul 2024
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    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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    sciencedirect.com/science/article/pii/S2211124724008945
  32. Jun 2024
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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    sciencedirect.com/science/article/pii/S2589004224010502
  34. Mar 2024
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regional modulation of toll-like receptor signaling pathway genes in acute epididymitis in mice
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    onlinelibrary.wiley.com/doi/10.1111/andr.13630
  36. May 2023
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    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
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    sciencedirect.com/science/article/pii/S1535610823001630
  38. Nov 2022
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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    sciencedirect.com/science/article/pii/S2211124722015467
  40. Sep 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    ncbi.nlm.nih.gov/pmc/articles/PMC9442361/
  42. Jul 2022
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15912
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    Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity
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    nature.com/articles/s41419-022-05063-6
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    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
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    sciencedirect.com/science/article/pii/S2589004222008793
  46. Jun 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    sciencedirect.com/science/article/pii/S2589004222007908
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9147548/
  49. Apr 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
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    sciencedirect.com/science/article/pii/S2211124722004569
  51. Jan 2022
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    sciencedirect.com/science/article/pii/S0753332222000038
  53. Dec 2021
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    Olfactory receptor 5B21 drives breast cancer metastasis
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    sciencedirect.com/science/article/pii/S2589004221014905
  55. Oct 2021
  56. academic.oup.com academic.oup.com
    Differential effects of viral nucleic acid sensor signaling pathways on testicular Sertoli and Leydig cells
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    academic.oup.com/endo/article/162/12/bqab180/6359040
  57. Sep 2021
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    sciencedirect.com/science/article/pii/S2211124721011694
  59. Jul 2021
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    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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    sciencedirect.com/science/article/pii/S2211124719314123
  61. www.jneurosci.org www.jneurosci.org
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    jneurosci.org/content/34/37/12490
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Palmitate‐induced C/EBP homologous protein activation leads to NF‐κB‐mediated increase in BACE1 activity and amyloid beta genesis
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14292/full
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Spinal interleukin-1β induces mechanical spinal hyperexcitability in rats: interactions and redundancies with TNF and IL-6
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15438
  64. Jun 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
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    ncbi.nlm.nih.gov/pmc/articles/PMC8192125/
  66. www.sciencedirect.com www.sciencedirect.com
    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
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    sciencedirect.com/science/article/pii/S2211124721006318
  67. Apr 2021
  68. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
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    sciencedirect.com/science/article/pii/S1550413120302473
  69. www.tandfonline.com www.tandfonline.com
    Ameliorative activity of aqueous leaf extract from Madhuca longifolia against diclofenac-administered toxicity on rat stomach and intestine
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    tandfonline.com/doi/full/10.1080/01478885.2020.1861917
  70. Mar 2021
  71. www.tandfonline.com www.tandfonline.com
    Ameliorative activity of aqueous leaf extract from Madhuca longifolia against diclofenac-administered toxicity on rat stomach and intestine
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    tandfonline.com/doi/full/10.1080/01478885.2020.1861917
  72. Oct 2020
  73. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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    pubmed.ncbi.nlm.nih.gov/33031745/
  74. Sep 2020
  75. www.cell.com www.cell.com
    NF-κB Dynamics Discriminate between TNF Doses in Single Cells
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    cell.com/cell-systems/abstract/S2405-4712(17)30448-9
  76. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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    sciencedirect.com/science/article/pii/S2211124720303703
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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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    sciencedirect.com/science/article/pii/S1550413120301224
  78. Jan 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus
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    sciencedirect.com/science/article/pii/S2211124719305443
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    sciencedirect.com/science/article/pii/S1534580718310359
  82. Nov 2018
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC6775781/
  84. www.sciencedirect.com www.sciencedirect.com
    Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A
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    sciencedirect.com/science/article/pii/S1074761318302504
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC5911925/
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    Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors
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    sciencedirect.com/science/article/pii/S1535610818302186
  87. www.sciencedirect.com www.sciencedirect.com
    Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
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    sciencedirect.com/science/article/pii/S155041311830192X
  88. www.karger.com www.karger.com
    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
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    karger.com/Article/FullText/487027
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    ncbi.nlm.nih.gov/pmc/articles/PMC5702193/
  91. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner
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    jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-017-1008-1
  92. Nov 2017
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance P Exacerbates Dopaminergic Neurodegeneration through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase
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    ncbi.nlm.nih.gov/pmc/articles/PMC4160779/