204 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pentagalloyl glucose inhibits monosodium urate-induced inflammation and NLRP3 inflammasome formation via TAK1 | American Journal of Physiology-Cell Physiology | American Physiological Society
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    pmc.ncbi.nlm.nih.gov/articles/PMC12318505/
  3. Jul 2025
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    Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors
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    sciencedirect.com/science/article/pii/S1535610825002739
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    Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners
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    sciencedirect.com/science/article/pii/S2666379125003143
  6. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013823-main-html.html
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  7. Jun 2025
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    Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers
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    sciencedirect.com/science/article/pii/S2666634025001795
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    VCPIP1 potentiates innate immune responses by non-catalytically reducing the ubiquitination of IRAK1/2
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    sciencedirect.com/science/article/pii/S2211124725007028
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
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    Piezo1 senses hyphae and initiates host defense against pathogenic fungi
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  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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  14. May 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TNF‐α‐Driven Changes in Polarized EGF Receptor Trafficking Facilitate Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling From the Apical Surface of MDCK Epithelial Cells
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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048508/
  18. Mar 2025
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    Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1
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    ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity
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  21. Feb 2025
  22. 52.53.155.43 52.53.155.43
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    SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis
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  24. Jan 2025
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    Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity
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    Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling
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  27. Dec 2024
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    The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCDC134 controls TLR biogenesis through the ER chaperone Gp96
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    MAPK pathways regulated apoptosis and pyroptosis in respiratory epithelial cells of a primitive vertebrate model during bacterial infection
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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  33. Nov 2024
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    HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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  36. Sep 2024
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    Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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  40. Aug 2024
  41. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells
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  42. Jul 2024
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    Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylation
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1
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  47. Jun 2024
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    Astrocytes-Secreted WNT5B Disrupts the Blood–Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection
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    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity
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    The ribotoxic stress response drives UV-mediated cell death
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    Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
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  53. May 2024
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    Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
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  55. journals.asm.org journals.asm.org
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    journals.asm.org/doi/10.1128/mbio.00299-24
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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  58. www.science.org www.science.org
    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    science.org/doi/10.1126/science.adi2421
  59. Apr 2024
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
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    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
  64. Mar 2024
  65. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
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    Epithelial-derived interleukin-23 promotes oral mucosal immunopathology
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
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  70. Feb 2024
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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  72. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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  77. Jan 2024
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    Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
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  83. dx.doi.org dx.doi.org
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    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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  85. Dec 2023
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    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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  87. Nov 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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    Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
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  93. Oct 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis
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    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
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    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
  97. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Mechanochemical coupling of MGF mediates periodontal regeneration
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    aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10603
  98. Sep 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose
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    ncbi.nlm.nih.gov/pmc/articles/PMC10361449/
  102. Aug 2023
  103. link.springer.com link.springer.com
    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
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    link.springer.com/article/10.1007/s10967-023-09067-0
  104. aacrjournals.org aacrjournals.org
    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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    aacrjournals.org/mct/article/22/8/962/727921/Vincristine-Enhances-the-Efficacy-of-MEK
  105. Jul 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of VPS13C promotes cisplatin resistance in cervical cancer by upregulating GSTP1
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    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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