161 Matching Annotations
  1. Last 7 days
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    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    1. scibot 03 May 2024
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      DOI: 10.1126/science.adi2421

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  3. Apr 2024
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    1. scibot 23 Apr 2024
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    sciencedirect.com/science/article/pii/S0006295224002132
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    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    1. scibot 13 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
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    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
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    1. scibot 12 Apr 2024
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    sciencedirect.com/science/article/pii/S0753332224004591
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    1. scibot 10 Apr 2024
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  8. Mar 2024
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    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
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    Epithelial-derived interleukin-23 promotes oral mucosal immunopathology
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    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S0092867424002253
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    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
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    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002572
  14. Feb 2024
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    sciencedirect.com/science/article/pii/S2211124724001232
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    BPS Publications
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    1. scibot 16 Feb 2024
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16282
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    Stromal-derived MAOB promotes prostate cancer growth and progression
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    1. scibot 14 Feb 2024
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      DOI: 10.1126/sciadv.adi4935

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    Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells
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    sciencedirect.com/science/article/pii/S1097276524000510
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    sciencedirect.com/science/article/pii/S2211124724000421
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  21. Jan 2024
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    Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
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    sciencedirect.com/science/article/pii/S2211124724000287
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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    sciencedirect.com/science/article/pii/S1097276523011218
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
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    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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  26. 52.53.155.43 52.53.155.43
    bqae003-html.html
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  27. dx.doi.org dx.doi.org
    cwad087-html.html
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    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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    sciencedirect.com/science/article/pii/S0303720723002915
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2666379123004974
  31. Nov 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    sciencedirect.com/science/article/pii/S258900422302429X
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    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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    Exploring the role of SWI/SNF complex subunit BAF60c in lipid metabolism and inflammation in fish
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  37. Oct 2023
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    Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis
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    EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway
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    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
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    Mechanochemical coupling of MGF mediates periodontal regeneration
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  42. Sep 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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    sciencedirect.com/science/article/pii/S2589004223018370
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    Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose
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    ncbi.nlm.nih.gov/pmc/articles/PMC10361449/
  46. Aug 2023
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    γ-radiation-induced damage on normal hepatocytes and its protection by ethyl cinnamate
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    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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  49. Jul 2023
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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  55. Apr 2023
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    ANKRD49 promotes the metastasis of NCI-H1299 and NCI-H1703 cells via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
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    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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  60. Jan 2023
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    Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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  63. Nov 2022
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    Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
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  68. Sep 2022
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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    Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1 β-Induced Endothelium Injury
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    Identification of a Novel Axon Regeneration Role for Non-Canonical Wnt Signaling in the Adult Retina After Injury
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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  97. Nov 2021
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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  99. Oct 2021
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    Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
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  102. Sep 2021
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    The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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  107. Aug 2021
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    ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  115. Jul 2021
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    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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    Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue
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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
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  122. Jun 2021
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    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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  128. May 2021
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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    Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities
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  142. Mar 2021
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  147. Feb 2021
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    Hormetic Effects of Binaphthyl Phosphonothioates as Pro-oxidants and Antioxidants
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    Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
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    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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    IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium
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  162. link.springer.com link.springer.com
    Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway
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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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    Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Loganetin protects against rhabdomyolysis‐induced acute kidney injury by modulating the toll‐like receptor 4 signalling pathway
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    Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation
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    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
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      RRID:AB_823588
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    sciencedirect.com/science/article/pii/S2405471216304082