179 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    1. scibot 10 Nov 2024
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      DOI: 10.2147/JIR.S481101

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539848/
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
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    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110644

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    ncbi.nlm.nih.gov/pmc/articles/PMC11388196/
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    1. scibot 12 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724010726
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009048
  7. Aug 2024
  8. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells
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    1. scibot 02 Aug 2024
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    cancerci.biomedcentral.com/articles/10.1186/s12935-021-02286-z
  9. Jul 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylation
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    1. scibot 24 Jul 2024
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    sciencedirect.com/science/article/pii/S258900422401592X
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    1. scibot 23 Jul 2024
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    sciencedirect.com/science/article/pii/S2666379124003276
  12. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 23 Jul 2024
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      DOI: 10.1002/1873-3468.14978

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    Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1
    1
    1. scibot 16 Jul 2024
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    sciencedirect.com/science/article/pii/S0969212624002284
  14. Jun 2024
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    Astrocytes-Secreted WNT5B Disrupts the Blood–Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection
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    1. scibot 28 Jun 2024
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    link.springer.com/article/10.1007/s12035-024-04303-4
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    1. scibot 09 Jun 2024
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      DOI: 10.1038/s44320-024-00040-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
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    The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity
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    1. scibot 07 Jun 2024
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      DOI: 10.1371/journal.ppat.1012271

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    ncbi.nlm.nih.gov/pmc/articles/PMC11175508/
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    The ribotoxic stress response drives UV-mediated cell death
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    1. scibot 06 Jun 2024
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    sciencedirect.com/science/article/pii/S0092867424005270
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    Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
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    1. scibot 04 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006156
  20. May 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
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    1. scibot 30 May 2024
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    sciencedirect.com/science/article/pii/S1534580724002995
  22. journals.asm.org journals.asm.org
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    1. scibot 24 May 2024
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      DOI: 10.1128/mbio.00299-24

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    journals.asm.org/doi/10.1128/mbio.00299-24
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.04.016

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    sciencedirect.com/science/article/pii/S1074761324002218
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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    sciencedirect.com/science/article/pii/S1550413124001347
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    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
    1
    1. scibot 03 May 2024
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      DOI: 10.1126/science.adi2421

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    science.org/doi/10.1126/science.adi2421
  26. Apr 2024
  27. www.sciencedirect.com www.sciencedirect.com
    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    1. scibot 23 Apr 2024
      4668

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    sciencedirect.com/science/article/pii/S0006295224002132
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
    1
    1. scibot 13 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  29. www.sciencedirect.com www.sciencedirect.com
    S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis
    1
    1. scibot 12 Apr 2024
      CST, #4668

      DOI: 10.1016/j.biopha.2024.116575

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    sciencedirect.com/science/article/pii/S0753332224004591
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    1. scibot 10 Apr 2024
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      DOI: 10.1016/j.isci.2024.109502

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
  31. Mar 2024
  32. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
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      DOI: 10.1210/endocr/bqae035

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    Epithelial-derived interleukin-23 promotes oral mucosal immunopathology
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    1. scibot 21 Mar 2024
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    sciencedirect.com/science/article/pii/S1074761324000967
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response
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    sciencedirect.com/science/article/pii/S2211124724002572
  37. Feb 2024
  38. www.sciencedirect.com www.sciencedirect.com
    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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    sciencedirect.com/science/article/pii/S2211124724001232
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16282

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16282
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
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    Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells
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    sciencedirect.com/science/article/pii/S1097276524000510
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    sciencedirect.com/science/article/pii/S2211124724000421
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    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  44. Jan 2024
  45. www.sciencedirect.com www.sciencedirect.com
    Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting
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    sciencedirect.com/science/article/pii/S2211124724000287
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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      DOI: 10.1016/j.molcel.2023.12.041

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    sciencedirect.com/science/article/pii/S1097276523011218
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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  72. Jul 2023
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    A dRASSF-STRIPAK-Imd-JAK/STAT axis controls antiviral immune response in Drosophila
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  102. Jul 2022
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    Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation
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    Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment
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  106. Jun 2022
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    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
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  108. May 2022
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    SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production
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  110. Apr 2022
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    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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  112. Mar 2022
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    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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  116. Feb 2022
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    Wnt7a inhibits transformed cell proliferation while promoting migration and invasion in non-small cell lung cancer
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  118. Dec 2021
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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  120. Nov 2021
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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  122. Oct 2021
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    Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome
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    Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity
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  125. Sep 2021
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    The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
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  127. journals.sagepub.com journals.sagepub.com
    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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    Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns
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    Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
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  130. Aug 2021
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    ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease
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    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  138. Jul 2021
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    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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    Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue
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    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
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    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  145. Jun 2021
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    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
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  150. www.nature.com www.nature.com
    Reprogramming of microRNA expression via E2F1 downregulation promotes Salmonella infection both in infected and bystander cells
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  151. May 2021
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    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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  175. Dec 2020
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    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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  181. Oct 2020
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    IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium
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  184. Sep 2020
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    Angiostrongylus cantonensis Galectin-1 interacts with Annexin A2 to impair the viability of macrophages via activating JNK pathway
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    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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    CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
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    Loganetin protects against rhabdomyolysis‐induced acute kidney injury by modulating the toll‐like receptor 4 signalling pathway
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  211. Nov 2018
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    Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation
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    Micro Integral Membrane Protein (MIMP), a Newly Discovered Anti-Inflammatory Protein of Lactobacillus Plantarum, Enhances the Gut Barrier and Modulates Microbiota and Inflammatory Cytokines
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    Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
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    NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
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  216. Nov 2017
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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