88 Matching Annotations
  1. Apr 2024
  2. dx.doi.org dx.doi.org
    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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    1. scibot 10 Apr 2024
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      DOI: 10.1210/endocr/bqae040

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    2. scibot 10 Apr 2024
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      DOI: 10.1210/endocr/bqae040

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    dx.doi.org/10.1210/endocr/bqae040
  3. www.sciencedirect.com www.sciencedirect.com
    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
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    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.014

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    sciencedirect.com/science/article/pii/S1534580724001801
  4. Feb 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
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    1. scibot 29 Feb 2024
      RRID:AB_823664

      DOI: 10.1016/j.canlet.2024.216762

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    sciencedirect.com/science/article/pii/S0304383524001551
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101396

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    sciencedirect.com/science/article/pii/S2666379124000053
  7. link.springer.com link.springer.com
    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00500-5

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    2. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00500-5

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    link.springer.com/article/10.1038/s41698-024-00500-5
  8. Jan 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108680

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046306/
  11. Dec 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming
    1
    1. scibot 22 Dec 2023
      RRID:AB_823664

      DOI: 10.1016/j.isci.2023.108656

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    sciencedirect.com/science/article/pii/S2589004223027335
  13. www.sciencedirect.com www.sciencedirect.com
    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.ccell.2023.11.004

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    sciencedirect.com/science/article/pii/S1535610823003951
  14. Nov 2023
  15. 52.53.155.43 52.53.155.43
    mvad090-html.html
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    1. scibot 10 Nov 2023
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      DOI: 10.1093/jb/mvad090

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    2. scibot 10 Nov 2023
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      DOI: 10.1093/jb/mvad090

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    52.53.155.43/c37b54a85bb2ab75b40e99c8cb130778e791e084/mvad090-html.html
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.cmet.2022.09.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC9633425/
  17. Jun 2023
  18. www.sciencedirect.com www.sciencedirect.com
    PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.devcel.2023.05.006

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    sciencedirect.com/science/article/pii/S1534580723002393
  19. May 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.isci.2023.106791

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    sciencedirect.com/science/article/pii/S2589004223008684
  21. www.sciencedirect.com www.sciencedirect.com
    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
    1
    1. scibot 10 May 2023
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      DOI: 10.1016/j.celrep.2023.112490

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    sciencedirect.com/science/article/pii/S2211124723005016
  22. www.science.org www.science.org
    Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
    1
    1. scibot 04 May 2023
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      DOI: 10.1126/scisignal.abq1366

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    science.org/doi/10.1126/scisignal.abq1366
  23. Apr 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
    2
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.cmet.2023.03.014

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    2. scibot 15 Apr 2023
      RRID:AB_823664

      DOI: 10.1016/j.cmet.2023.03.014

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    sciencedirect.com/science/article/pii/S155041312300092X
  25. Mar 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
    1
    1. scibot 09 Mar 2023
      RRID:AB_823664

      DOI: 10.1016/j.isci.2023.106193

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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  27. Feb 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
    1
    1. scibot 11 Feb 2023
      RRID:AB_823664

      DOI: 10.1016/j.isci.2023.105965

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    sciencedirect.com/science/article/pii/S2589004223000421
  29. www.biorxiv.org www.biorxiv.org
    A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs
    1
    1. scibot 07 Feb 2023
      RRID:AB_823664

      DOI: 10.1101/2023.01.24.525374

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    biorxiv.org/content/10.1101/2023.01.24.525374v1
  30. Jan 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.cell.2022.12.030

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    sciencedirect.com/science/article/pii/S0092867422015732
  32. Dec 2022
  33. www.sciencedirect.com www.sciencedirect.com
    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
    1
    1. scibot 20 Dec 2022
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      DOI: 10.1016/j.devcel.2022.11.015

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    sciencedirect.com/science/article/pii/S1534580722008152
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111818

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265649/
  35. www.sciencedirect.com www.sciencedirect.com
    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111756

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    sciencedirect.com/science/article/pii/S2211124722016394
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
    1
    1. scibot 02 Dec 2022
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      DOI: 10.3389/fnmol.2022.1039135

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    ncbi.nlm.nih.gov/pmc/articles/PMC9709411/
  37. Nov 2022
  38. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
    1
    1. scibot 10 Nov 2022
      RRID:AB_823664

      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  39. Oct 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111545

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    sciencedirect.com/science/article/pii/S2211124722014012
  41. Jul 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    1. scibot 31 Jul 2022
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      DOI: 10.3390/ijms23147774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
  43. Jun 2022
  44. www.sciencedirect.com www.sciencedirect.com
    M2 macrophage-derived exosomal microRNA-411-5p impedes the activation of hepatic stellate cells by targeting CAMSAP1 in NASH model
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    1. scibot 25 Jun 2022
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      DOI: 10.1016/j.isci.2022.104597

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    sciencedirect.com/science/article/pii/S2589004222008690
  45. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
    1
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      DOI: 10.1016/j.molcel.2022.05.008

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    sciencedirect.com/science/article/pii/S1097276522004427
  46. May 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor
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      DOI: 10.1016/j.celrep.2022.110771

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    sciencedirect.com/science/article/pii/S2211124722005356
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury
    1
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      DOI: 10.1016/j.neuron.2022.03.021

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    sciencedirect.com/science/article/pii/S0896627322002574
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    ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
    1
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      Cell Signaling TechnologiesCat# 2128

      DOI: 10.1016/j.celrep.2022.110598

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    sciencedirect.com/science/article/pii/S2211124722003461
  51. Feb 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Systematic illumination of druggable genes in cancer genomes
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      DOI: 10.1016/j.celrep.2022.110400

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    sciencedirect.com/science/article/pii/S2211124722001218
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Supplementing Soy-Based Diet with Creatine in Rats: Implications for Cardiac Cell Signaling and Response to Doxorubicin
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      DOI: 10.3390/nu14030583

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    ncbi.nlm.nih.gov/pmc/articles/PMC8840593/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Electroacupuncture treatment improves motor function and neurological outcomes after cerebral ischemia/reperfusion injury
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    1. scibot 05 Feb 2022
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      DOI: 10.4103/1673-5374.330617

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    ncbi.nlm.nih.gov/pmc/articles/PMC8771092/
  55. Jan 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
    1
    1. scibot 05 Jan 2022
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      DOI: 10.1016/j.ccell.2019.04.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC8717880/
  57. Dec 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
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    1. scibot 29 Dec 2021
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      DOI: 10.1016/j.isci.2021.103605

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    sciencedirect.com/science/article/pii/S2589004221015753
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
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    Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress - Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang, 2021
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    Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
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    Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation
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    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
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    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      DOI: 10.1016/j.celrep.2019.04.041

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  111. Nov 2018
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    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
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    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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    Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
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