104 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights
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    1. scibot 09 Oct 2024
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    sciencedirect.com/science/article/pii/S155041312400370X
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2019.07.068

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    sciencedirect.com/science/article/pii/S2211124719309726
  5. Jul 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesoporous manganese nanocarrier target delivery metformin for the co-activation STING pathway to overcome immunotherapy resistance
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    1. scibot 26 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261061/
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    Comparative transcriptomic profiling reveals a role for Olig1 in promoting axon regeneration
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    1. scibot 17 Jul 2024
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    sciencedirect.com/science/article/pii/S221112472400843X
  8. www.cell.com www.cell.com
    TSPAN4 influences glioblastoma progression through regulating EGFR stability
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    1. scibot 16 Jul 2024
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    cell.com/iscience/fulltext/S2589-0042(24)01642-0
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    1. scibot 07 Jul 2024
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      DOI: 10.1158/1541-7786.MCR-23-0512

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    ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
    2
    1. scibot 04 Jul 2024
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      DOI: 10.1016/j.nbd.2024.106586

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    sciencedirect.com/science/article/pii/S0969996124001864
  11. Jun 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fully automated viability and toxicity screening—A reliable all‐in‐one attempt
    1
    1. scibot 25 Jun 2024
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      DOI: 10.1002/cam4.7392

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    ncbi.nlm.nih.gov/pmc/articles/PMC11193055/
  13. www.sciencedirect.com www.sciencedirect.com
    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006739
  14. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
    1
    1. scibot 14 Jun 2024
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      DOI: 10.7554/eLife.88375

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  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization
    1
    1. scibot 13 Jun 2024
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      DOI: 10.1007/s00403-024-03032-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161541/
  16. May 2024
  17. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 30 May 2024
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      DOI: 10.1111/bph.16420

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16420
  18. www.sciencedirect.com www.sciencedirect.com
    Protocol for mass spectrometric profiling of lysine malonylation by lysine acetyltransferase in CRISPRi K562 cell lines
    1
    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S2666166724002399
  19. www.sciencedirect.com www.sciencedirect.com
    Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
    1
    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1535610824001624
  20. www.sciencedirect.com www.sciencedirect.com
    HuR promotes triglyceride synthesis and intestinal fat absorption
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    1. scibot 16 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005667
  21. Apr 2024
  22. dx.doi.org dx.doi.org
    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
    2
    1. scibot 10 Apr 2024
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      DOI: 10.1210/endocr/bqae040

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  23. www.sciencedirect.com www.sciencedirect.com
    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
    1
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    sciencedirect.com/science/article/pii/S1534580724001801
  24. Feb 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.canlet.2024.216762

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    sciencedirect.com/science/article/pii/S0304383524001551
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.xcrm.2024.101396

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    sciencedirect.com/science/article/pii/S2666379124000053
  27. www.nature.com www.nature.com
    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
    2
    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00500-5

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    nature.com/articles/s41698-024-00500-5
  28. Jan 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circGlis3 promotes β-cell dysfunction by inhibiting hnRNPF nuclear translocation and encoding Glis3-348aa protein
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108680

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788204/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
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    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046306/
  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming
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    1. scibot 22 Dec 2023
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    sciencedirect.com/science/article/pii/S2589004223027335
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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      DOI: 10.1016/j.ccell.2023.11.004

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    sciencedirect.com/science/article/pii/S1535610823003951
  34. Nov 2023
  35. 52.53.155.43 52.53.155.43
    mvad090-html.html
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    1. scibot 10 Nov 2023
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      DOI: 10.1093/jb/mvad090

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    52.53.155.43/c37b54a85bb2ab75b40e99c8cb130778e791e084/mvad090-html.html
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9633425/
  37. Jun 2023
  38. www.sciencedirect.com www.sciencedirect.com
    PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
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    sciencedirect.com/science/article/pii/S1534580723002393
  39. May 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation
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    sciencedirect.com/science/article/pii/S2211124723005016
  42. www.science.org www.science.org
    Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
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      DOI: 10.1126/scisignal.abq1366

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    science.org/doi/10.1126/scisignal.abq1366
  43. Apr 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Metformin triggers a kidney GDF15-dependent area postrema axis to regulate food intake and body weight
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    sciencedirect.com/science/article/pii/S155041312300092X
  45. Mar 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone malonylation is regulated by SIRT5 and KAT2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
  47. Feb 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix
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    sciencedirect.com/science/article/pii/S2589004223000421
  49. www.biorxiv.org www.biorxiv.org
    A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs
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      DOI: 10.1101/2023.01.24.525374

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    biorxiv.org/content/10.1101/2023.01.24.525374v1
  50. Jan 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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    sciencedirect.com/science/article/pii/S0092867422015732
  52. Dec 2022
  53. www.sciencedirect.com www.sciencedirect.com
    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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  57. Nov 2022
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  59. Oct 2022
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    Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein
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  61. Jul 2022
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    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    Evidence for reduced BRCA2 functional activity in Homo sapiens after divergence from the chimpanzee-human last common ancestor
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  77. Dec 2021
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    Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress - Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang, 2021
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    Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
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  94. Jul 2021
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    Decreased Expression of the Host Long-Noncoding RNA-GM Facilitates Viral Escape by Inhibiting the Kinase activity TBK1 via S-glutathionylation
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  112. Sep 2020
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  114. www.sciencedirect.com www.sciencedirect.com
    Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis
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      DOI: 10.1016/j.celrep.2020.107623

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  115. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
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      DOI: 10.1038/s41467-019-14085-2

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  117. www.sciencedirect.com www.sciencedirect.com
    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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      DOI: 10.1016/j.celrep.2020.01.054

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    Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment
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  119. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription
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      β-Tubulin

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    Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
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    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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      DOI: 10.1016/j.cell.2020.03.062

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  122. Jan 2020
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    The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
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      DOI: 10.1016/j.stem.2019.08.018

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    A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery
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      DOI: 10.1016/j.chembiol.2019.07.008

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    Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention
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      DOI: 10.1016/j.cmet.2019.12.005

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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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      DOI: 10.1016/j.cmet.2019.05.018

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  127. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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      DOI: 10.1016/j.cels.2019.11.001

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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
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      DOI: 10.1016/j.celrep.2019.07.031

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  129. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      RRID:AB_823664

      DOI: 10.1016/j.ccell.2019.01.020

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  130. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_823664

      DOI: 10.1016/j.celrep.2019.04.041

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    sciencedirect.com/science/article/pii/S2211124719305066
  131. Nov 2018
  132. www.sciencedirect.com www.sciencedirect.com
    COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking
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  133. europepmc.org europepmc.org
    Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
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      2128

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  134. www.sciencedirect.com www.sciencedirect.com
    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    sciencedirect.com/science/article/pii/S1097276518302326
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    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
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    sciencedirect.com/science/article/pii/S1550413118301323
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    Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
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    sciencedirect.com/science/article/pii/S0092867418303088
  137. Nov 2017
  138. www.sciencedirect.com www.sciencedirect.com
    Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
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      AB_823664

      Curator: @chewbeccax

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