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Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

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Jul 2025
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P75NTR activation limits CD21lo B cell subsets expansion in response to autoimmune-inducing challenges

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pmc.ncbi.nlm.nih.gov/articles/PMC12303049/
May 2025
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Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression

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PIM kinase control of CD8 T cell protein synthesis and cell trafficking

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.98622
  
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1-s2.0-S2589004225007692-main-html.html

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Apr 2025
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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sciencedirect.com/science/article/pii/S2211124725002815
Mar 2025
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Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

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Translation dysregulation in cancer as a source for targetable antigens

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Feb 2025
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis

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NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection

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Jan 2025
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Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.cmet.2024.12.007
  
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Dec 2024
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Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells

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science.org/doi/10.1126/scisignal.adi8753
Aug 2024
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

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1. scibot 20 Aug 2024
  
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Apr 2024
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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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1. scibot 02 Apr 2024
  
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  DOI: 10.1126/scisignal.adh0439
  
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science.org/doi/10.1126/scisignal.adh0439
Jan 2024
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A time- and single-cell-resolved model of murine bone marrow hematopoiesis

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.stem.2023.12.001
  
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Oct 2023
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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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1. scibot 17 Oct 2023
  
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science.org/doi/10.1126/sciimmunol.abh0707
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Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma

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1. scibot 13 Oct 2023
  
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Detection of the CD8+ T cell immune response in mice infected with OVA-Listeriamonocytogenes

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ncbi.nlm.nih.gov/pmc/articles/PMC10550835/
Sep 2023
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Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

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Aug 2023
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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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Jul 2023
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Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin

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May 2023
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Identification of an adipose tissue-resident pro-preadipocyte population

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Jan 2023
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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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Aug 2022
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Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury

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Jul 2022
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Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion

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ncbi.nlm.nih.gov/pmc/articles/PMC9301332/
Jun 2022
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Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses

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May 2022
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Localization of a TORC1-eIF4F translation complex during CD8+ T cell activation drives divergent cell fate

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Apr 2022
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Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

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  DOI: 10.1016/j.celrep.2022.110747
  
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Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1

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ncbi.nlm.nih.gov/pmc/articles/PMC8736284/
Mar 2022
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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

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  DOI: 10.1158/2326-6066.CIR-20-0925
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8416791/
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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

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  DOI: 10.7554/eLife.75508
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
Nov 2021
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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.67476
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8553335/
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Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation

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The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo

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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis

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Untitled document

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The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility

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1. scibot 31 Jul 2021
  
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  Anti-CD44 (clone IM7)
  
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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity

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Transcription factor Ascl2 promotes germinal center B cell responses by directly regulating AID transcription

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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

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Dynamic adoption of anergy by antigen-exhausted CD4+ T cells

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cell.com/cell-reports/fulltext/S2211-1247(21)00061-9
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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

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High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision

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Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae

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Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity

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PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

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cell.com/molecular-cell/fulltext/S1097-2765(19)30925-6
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Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

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Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression

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Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response

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Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2

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