120 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
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    1. scibot 21 Nov 2024
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      DOI: 10.1038/s44318-024-00246-7

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    pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.xcrm.2024.101826

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    sciencedirect.com/science/article/pii/S2666379124005974
  5. Oct 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1016/j.cmet.2024.09.002

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    sciencedirect.com/science/article/pii/S1550413124003668
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    1. scibot 27 Sep 2024
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    sciencedirect.com/science/article/pii/S2666379124004774
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    Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages
    1
    1. scibot 26 Sep 2024
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    sciencedirect.com/science/article/pii/S1550413124003620
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    Endothelial metabolic control of insulin sensitivity through resident macrophages
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    1. scibot 13 Sep 2024
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    sciencedirect.com/science/article/pii/S1550413124003358
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.isci.2024.110810

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    pmc.ncbi.nlm.nih.gov/articles/PMC11404196/
  12. Aug 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
    1
    1. scibot 23 Aug 2024
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      DOI: 10.7554/eLife.76940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  14. Jul 2024
  15. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.immuni.2024.07.001

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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
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    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.immuni.2024.04.003

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    sciencedirect.com/science/article/pii/S1074761324002085
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    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
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    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113963

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    sciencedirect.com/science/article/pii/S2211124724002912
  21. Jan 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113627

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    sciencedirect.com/science/article/pii/S2211124723016388
  23. www.sciencedirect.com www.sciencedirect.com
    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.chom.2023.12.006

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    sciencedirect.com/science/article/pii/S1931312823005012
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Stress-induced β cell early senescence confers protection against type 1 diabetes
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.cmet.2023.10.014

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    sciencedirect.com/science/article/pii/S1550413123003832
  26. Oct 2023
  27. 52.53.155.43 52.53.155.43
    CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1101/2023.09.01.555931

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    52.53.155.43/af30fe5b925ee191151336cec774a7057661b188/2023.09.01.555931v1.full-html.html
  28. www.science.org www.science.org
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciimmunol.abh0707

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    science.org/doi/10.1126/sciimmunol.abh0707
  29. www.sciencedirect.com www.sciencedirect.com
    ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113206

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    sciencedirect.com/science/article/pii/S2211124723012184
  30. Sep 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing
    1
    1. scibot 23 Sep 2023
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      DOI: 10.1016/j.xpro.2023.102165

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    ncbi.nlm.nih.gov/pmc/articles/PMC10510057/
  32. Aug 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112990

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    sciencedirect.com/science/article/pii/S221112472301001X
  34. 52.53.155.43 52.53.155.43
    A MYC-controlled redox switch protects B lymphoma cells from EGR1-dependent apoptosis
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112961

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112961

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    52.53.155.43/e4339d2342058d0ba733e06b854674a1d2f752a1/PIIS2211124723009725-html.html
  35. Jul 2023
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.020

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    pmc.ncbi.nlm.nih.gov/articles/PMC10433941/
  37. www.sciencedirect.com www.sciencedirect.com
    Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.023

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    sciencedirect.com/science/article/pii/S1074761323002807
  38. Jun 2023
  39. 52.53.155.43 52.53.155.43
    Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of Alveolar Macrophages
    1
    1. scibot 30 Jun 2023
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      DOI: 10.1016/j.isci.2023.107197

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    52.53.155.43/b1855eddc70d7186ec64ad10a33c00437bfe6cd4/1-s2.0-S2589004223012749-main-html.html
  40. Apr 2023
  41. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.immuni.2023.01.033

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    sciencedirect.com/science/article/pii/S1074761323000456
  42. Feb 2023
  43. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
    1
    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.cmet.2023.01.010

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    sciencedirect.com/science/article/pii/S1550413123000104
  44. Dec 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis
    1
    1. scibot 16 Dec 2022
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      DOI: 10.7554/eLife.82193

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    ncbi.nlm.nih.gov/pmc/articles/PMC9750176/
  46. Oct 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection
    1
    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.cell.2022.09.008

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    sciencedirect.com/science/article/pii/S0092867422011308
  48. Sep 2022
  49. www.nature.com www.nature.com
    BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis
    1
    1. scibot 24 Sep 2022
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      DOI: 10.1038/s41598-022-20017-w

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    nature.com/articles/s41598-022-20017-w
  50. www.sciencedirect.com www.sciencedirect.com
    Design, construction, and in vivo augmentation of a complex gut microbiome
    1
    1. scibot 07 Sep 2022
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      DOI: 10.1016/j.cell.2022.08.003

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    sciencedirect.com/science/article/pii/S0092867422009904
  51. Aug 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBM
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.ebiom.2022.104239

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    sciencedirect.com/science/article/pii/S2352396422004212
  53. Jul 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
    1
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      DOI: 10.1016/j.devcel.2022.06.006

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    sciencedirect.com/science/article/pii/S1534580722004464
  55. Jun 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Envelope virus-mimetic nanovaccines by hybridizing bioengineered cell membranes with bacterial vesicles
    1
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      DOI: 10.1016/j.isci.2022.104490

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    sciencedirect.com/science/article/pii/S2589004222007611
  57. www.sciencedirect.com www.sciencedirect.com
    PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110914

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    sciencedirect.com/science/article/pii/S221112472200691X
  58. May 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy
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    1. scibot 20 May 2022
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      DOI: 10.1016/j.ccell.2022.04.018

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    sciencedirect.com/science/article/pii/S1535610822002112
  60. Apr 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
    1
    1. scibot 16 Apr 2022
      RRID:AB_893232

      DOI: 10.1126/sciimmunol.abh0707

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    ncbi.nlm.nih.gov/pmc/articles/PMC8736284/
  62. Jan 2022
  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Jan 2022
      RRID:AB_893232

      DOI: 10.1111/bph.15780

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15780
  64. www.sciencedirect.com www.sciencedirect.com
    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
    1
    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.celrep.2022.110302

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    sciencedirect.com/science/article/pii/S2211124722000146
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
    1
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  66. Dec 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models
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    Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain
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  69. www.sciencedirect.com www.sciencedirect.com
    Flow cytometry analysis of the subpopulations of mouse keratinocytes and skin immune cells
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  70. Nov 2021
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    Insular cortex neurons encode and retrieve specific immune responses
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  72. Oct 2021
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    Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis
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    Cold exposure protects from neuroinflammation through immunologic reprogramming
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  75. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vaccination induces rapid protection against bacterial pneumonia via training alveolar macrophage in mice
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    Targeting B cells in the Pre-Phase of Systemic Autoimmunity Globally Interferes with Autoimmune Pathology
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    Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion
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  80. Aug 2021
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    High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis
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    Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors
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    Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
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    A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
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    Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin
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  89. Jul 2021
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    The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response
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    Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche
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      Rat anti-Mouse CD11b (M1/70)

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      Rat anti-Mouse CD11b (M1/70)

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    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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    The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease
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  94. May 2021
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    Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology
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    The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection
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    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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    Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
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  101. Apr 2021
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    TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma
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    Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
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  104. www.sciencedirect.com www.sciencedirect.com
    Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis
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    Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma
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    Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
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    Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells
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    Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
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    CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis
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    Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation
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  111. Mar 2021
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    Functional characterization of the dural sinuses as a neuroimmune interface
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  113. Feb 2021
  114. www.frontiersin.org www.frontiersin.org
    Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
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    Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
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  116. academic.oup.com academic.oup.com
    Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy
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  117. Dec 2020
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    Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation
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  119. Nov 2020
  120. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes
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  121. Oct 2020
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    In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells
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    Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response
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  124. Sep 2020
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    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
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    Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity
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    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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  128. elifesciences.org elifesciences.org
    Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo
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    Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
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    Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo
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    Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
    2
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    Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
    1
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    Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production
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      DOI: 10.1016/j.celrep.2020.02.013

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    An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint
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      DOI: 10.1016/j.cell.2020.04.030

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    Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes
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      DOI: 10.1016/j.cmet.2020.03.002

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  136. Jan 2020
  137. www.sciencedirect.com www.sciencedirect.com
    MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota
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      RRID:AB_893232

      DOI: 10.1016/j.immuni.2019.08.011

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    B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis
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    1. scibot 13 Jan 2020
      RRID:AB_893232

      DOI: 10.1016/j.celrep.2019.10.070

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    The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
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      DOI: 10.1016/j.celrep.2019.06.007

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease
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      DOI: 10.3389/fimmu.2019.02470

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    Innate Lymphoid Cells in the Induction of Obesity
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      DOI: 10.1016/j.celrep.2019.06.016

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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response
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      DOI: 10.7554/eLife.39982

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  143. Nov 2018
  144. www.sciencedirect.com www.sciencedirect.com
    A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy
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    Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression
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    Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production
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    Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
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    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
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    The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages
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  151. Nov 2017
  152. academic.oup.com academic.oup.com
    Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II–Induced Cardiac Diastolic Dysfunction in Male Mice
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    Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells
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  154. www.cell.com www.cell.com
    Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq
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