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Naturally self-reactive B cells are poised to cross the selection barrier into autoimmune germinal centers

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1. scibot 10 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117224
  
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sciencedirect.com/science/article/pii/S2211124726003025
Mar 2026
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A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.002
  
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sciencedirect.com/science/article/pii/S1074761326000543
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Eos plays a critical role in Treg homeostasis and modulates the function of recirculating thymic Tregs in the control of Treg development

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1. scibot 07 Feb 2026
  
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  DOI: 10.1016/j.celrep.2025.116838
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12869356/
Jan 2026
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Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.021
  
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sciencedirect.com/science/article/pii/S1535610825005550
Oct 2025
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TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.011
  
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sciencedirect.com/science/article/pii/S1535610825004039
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Local delivery of IL-15 and anti-PD-L1 nanobody by in vitro-transcribed circILNb elicits superior antitumor immunity in cold tumors

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102413
  
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sciencedirect.com/science/article/pii/S2666379125004860
Aug 2025
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Targeting fibroblast TNF receptor 1 attenuates type 17 skin inflammation

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1. scibot 20 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116111
  
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cell.com/cell-reports/abstract/S2211-1247(25)00882-4
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CD138 and APRIL regulate plasma cell survival, competition, and retention in the bone marrow niche

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1. scibot 06 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116123
  
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sciencedirect.com/science/article/pii/S2211124725008940
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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Distinct TAM subset with cross-dressing capability determines the bifurcation of tumor immunity

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115800
  
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sciencedirect.com/science/article/pii/S2211124725005716
May 2025
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Myeloid-lineage-specific membrane protein LRRC25 suppresses immunity in solid tumor and is a potential cancer immunotherapy checkpoint target

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115631
  
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sciencedirect.com/science/article/pii/S2211124725004024
Apr 2025
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Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115612
  
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sciencedirect.com/science/article/pii/S2211124725003833
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Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes

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1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115571
  
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sciencedirect.com/science/article/pii/S2211124725003420
Feb 2025
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115294
  
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sciencedirect.com/science/article/pii/S2211124725000658
52.53.155.43 52.53.155.43

1-s2.0-S2589004225002354-main-html.html

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111975
  
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52.53.155.43/49ea408b68f233098d1bbcd6742291cc57e6f9e8/1-s2.0-S2589004225002354-main-html.html
Jan 2025
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Bone marrow mesenchymal stromal cells support translation in refractory acute myeloid leukemia

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115151
  
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sciencedirect.com/science/article/pii/S221112472401502X
Jul 2024
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G2 arrest primes hematopoietic stem cells for megakaryopoiesis

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114388
  
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sciencedirect.com/science/article/pii/S2211124724007162
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity

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1. scibot 16 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293343/
Jun 2024
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Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.019
  
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sciencedirect.com/science/article/pii/S153458072400337X
Apr 2024
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Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.04.001
  
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sciencedirect.com/science/article/pii/S1074761324002061
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling

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1. scibot 16 Mar 2024
  
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  DOI: 10.1084/jem.20221466
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
Dec 2023
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Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113608
  
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sciencedirect.com/science/article/pii/S2211124723016200
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Sep 2023
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Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113127
  
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sciencedirect.com/science/article/pii/S2211124723011397
Aug 2023
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Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy

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1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.ccell.2023.08.001
  
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sciencedirect.com/science/article/abs/pii/S1535610823002738
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
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The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112905
  
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sciencedirect.com/science/article/pii/S2211124723009166
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas

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1. scibot 12 Jul 2023
  
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  DOI: 10.1158/2159-8290.CD-22-0561
  
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2. scibot 12 Jul 2023
  
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  DOI: 10.1158/2159-8290.CD-22-0561
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9839622/
May 2023
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

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1. scibot 26 May 2023
  
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  DOI: 10.1016/j.ccell.2023.04.019
  
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sciencedirect.com/science/article/pii/S1535610823001630
journals.physiology.org journals.physiology.org

Sex-specific Phenotypes in the Aging Mouse Heart and Consequences for Chronic Fibrosis

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1. scibot 05 May 2023
  
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  DOI: 10.1152/ajpheart.00078.2022
  
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journals.physiology.org/doi/full/10.1152/ajpheart.00078.2022
journals.physiology.org journals.physiology.org

Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis

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1. scibot 05 May 2023
  
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  DOI: 10.1152/ajpheart.00078.2022
  
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journals.physiology.org/doi/10.1152/ajpheart.00078.2022
Feb 2023
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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.029
  
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sciencedirect.com/science/article/pii/S1074761323000419
Dec 2022
52.53.155.43 52.53.155.43

cd-22-0561-html.html

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1. scibot 06 Dec 2022
  
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  DOI: 10.1158/2159-8290.CD-22-0561
  
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2. scibot 03 Dec 2022
  
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  DOI: 10.1158/2159-8290.CD-22-0561
  
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52.53.155.43/a429cb5e58e03f354312204fbbe86e9227a8ee47/cd-22-0561-html.html
Nov 2022
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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1. scibot 15 Nov 2022
  
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  DOI: 10.1016/j.immuni.2022.10.020
  
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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection

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Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis

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Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance

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Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength

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Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

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SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization

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Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

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Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors

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Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses

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Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

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Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

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Type I interferon decreases macrophage energy metabolism during mycobacterial infection

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Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

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Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

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Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

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Untitled document

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate

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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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Macrophages Facilitate Electrical Conduction in the Heart

1
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