Hypothesis

35 Matching Annotations

Last 7 days
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Downregulation of microRNA-494 drives mitochondrial biogenesis and function in trained muscle

1
1. scibot 30 Aug 2025
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1113/EP092977
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

physoc.onlinelibrary.wiley.com/doi/10.1113/EP092977
May 2025
www.cell.com www.cell.com

Personalized molecular signatures of insulin resistance and type 2 diabetes

1
1. scibot 30 May 2025
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.cell.2025.05.005
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

cell.com/cell/abstract/S0092-8674(25)00515-X
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.xcrm.2025.101941
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912500014X
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Opposing roles for AMPK in regulating distinct mitophagy pathways

1
1. scibot 20 Nov 2024
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.molcel.2024.10.025
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524008657
Aug 2024
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Exercise improves homeostasis of the intestinal epithelium by activation of APJ-AMPK signaling

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID: AB_915794
  
  DOI: 10.1113/JP284552
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP284552
Jan 2024
www.mdpi.com www.mdpi.com

BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation

1
1. scibot 07 Jan 2024
  
  in Public
  
  RRID:AB_915794GBF1
  
  DOI: 10.3390/ijms25010453
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Unresolved

Annotators

scibot

URL

mdpi.com/1422-0067/25/1/453
May 2023
52.53.155.43 52.53.155.43

The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html

1
1. scibot 11 May 2023
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1113/jp284552
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

52.53.155.43/e6c85c39692a8a492c117b9f4fb49e166812457c/The Journal of Physiology - 2023 - Chae - Exercise improves homeostasis of the intestinal epithelium by activation of-html.html
journals.physiology.org journals.physiology.org

Sex-specific Phenotypes in the Aging Mouse Heart and Consequences for Chronic Fibrosis

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1152/ajpheart.00078.2022
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

journals.physiology.org/doi/full/10.1152/ajpheart.00078.2022
journals.physiology.org journals.physiology.org

Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1152/ajpheart.00078.2022
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

journals.physiology.org/doi/10.1152/ajpheart.00078.2022
Mar 2023
www.nature.com www.nature.com

Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice

1
1. scibot 16 Mar 2023
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1038/s42003-023-04616-5
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

nature.com/articles/s42003-023-04616-5
Oct 2022
academic.oup.com academic.oup.com

Mineralocorticoid receptors mediates diet - induced lipid infiltration of skeletal muscle and insulin resistance

1
1. scibot 29 Oct 2022
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1210/endocr/bqac145
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

academic.oup.com/endo/article/163/11/bqac145/6678806
www.sciencedirect.com www.sciencedirect.com

Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments

1
1. scibot 06 Oct 2022
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.molmet.2022.101596
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221287782200165X
Feb 2022
www.sciencedirect.com www.sciencedirect.com

An AMPKα2-specific phospho-switch controls lysosomal targeting for activation

1
1. scibot 16 Feb 2022
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.celrep.2022.110365
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722000869
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

1
1. scibot 26 Jan 2022
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.ebiom.2022.103842
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396422000263
www.sciencedirect.com www.sciencedirect.com

The Alzheimer’s disease drug candidate J147 decreases blood plasma fatty acid levels via modulation of AMPK/ACC1 signaling in the liver

1
1. scibot 19 Jan 2022
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.biopha.2022.112648
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0753332222000361
Dec 2021
journals.physiology.org journals.physiology.org

Anemic Hypoxemia Reduces Myoblast Proliferation and Muscle Growth in Late Gestation Fetal Sheep

1
1. scibot 08 Dec 2021
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1152/ajpregu.00342.2020
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

journals.physiology.org/doi/abs/10.1152/ajpregu.00342.2020
Nov 2021
52.53.155.43 52.53.155.43

ajpregu.00342.2020-html.html

1
1. scibot 24 Nov 2021
  
  in Public
  
  AB_915794
  
  DOI: 10.1152/ajpregu.00342.2020
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

52.53.155.43/929b6923868831e320580be57c2774b268327ec6/ajpregu.00342.2020-html.html
www.sciencedirect.com www.sciencedirect.com

MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

1
1. scibot 12 Nov 2021
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.immuni.2021.10.011
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761321004489
Sep 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia

1
1. scibot 25 Sep 2021
  
  in Public
  
  AB_915794
  
  DOI: 10.14814/phy2.15033
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15033
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.isci.2021.102807
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 11 Aug 2021
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.molcel.2017.04.027
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

1
1. scibot 30 Jul 2021
  
  in Public
  
  AMPKα (F6) Mouse mAb
  
  DOI: 10.1016/j.ccell.2019.03.007
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819301527
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.celrep.2020.108461
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720314509
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

1
1. scibot 14 Sep 2020
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.cmet.2020.04.015
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120301972
Jan 2020
elifesciences.org elifesciences.org

Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.7554/eLife.45873
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

elifesciences.org/articles/45873
www.nature.com www.nature.com

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1038/s41467-019-13086-5
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

nature.com/articles/s41467-019-13086-5
www.sciencedirect.com www.sciencedirect.com

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_915794
  
  DOI: 10.1016/j.molcel.2019.08.005
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @ethanbadger
  
  SciCrunch record: AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519306215
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_915794
  
  DOI: 10.1152/ajpendo.00050.2018
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @evieth
  
  SciCrunch record: AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6415714/
www.sciencedirect.com www.sciencedirect.com

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_915794
  
  DOI: 10.1016/j.cmet.2019.07.004
  
  Resource: (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_915794
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119303778
Nov 2018
www.sciencedirect.com www.sciencedirect.com

AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_915794
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S193459091830239X
www.sciencedirect.com www.sciencedirect.com

A Metabolic Basis for Endothelial-to-Mesenchymal Transition

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_915794
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727651830039X
www.sciencedirect.com www.sciencedirect.com

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_915794
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945618301107
Nov 2017
link.springer.com link.springer.com

IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_915794
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794
Visit annotations in context

Tags

RRID:AB_915794

Annotators

scibot

URL

link.springer.com/article/10.1007/s00125-017-4345-9
www.sciencedirect.com www.sciencedirect.com

PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_915794
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041311730236X
www.sciencedirect.com www.sciencedirect.com

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_915794
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2793, RRID:AB_915794)
  
  SciCrunch record: RRID:AB_915794
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_915794 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_915794

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727651730312X