24 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease
    1
    1. scibot 23 May 2024
      RRID: AB_94263

      DOI: 10.1126/sciadv.adl2036

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100560/
  3. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 09 May 2024
      RRID:AB_94263

      DOI: 10.1126/sciadv.adl6082

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    science.org/doi/10.1126/sciadv.adl6082
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 05 May 2024
      RRID:AB_94263

      DOI: 10.1126/sciadv.adl6082

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  5. Feb 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene-dosage- and sex-dependent differences in the prodromal-Like phase of the F344tgHD rat model for Huntington disease
    1
    1. scibot 28 Feb 2024
      RRID:AB_94263

      DOI: 10.3389/fnins.2024.1354977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879377/
  7. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
    1
    1. scibot 02 Feb 2024
      RRID:AB_94263

      DOI: 10.1016/j.molcel.2024.01.006

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    sciencedirect.com/science/article/pii/S1097276524000078
  8. Sep 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
    1
    1. scibot 19 Sep 2023
      RRID:AB_94263

      DOI: 10.1016/j.abb.2023.109711

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    sciencedirect.com/science/article/pii/S0003986123002102
  10. Jul 2023
  11. pubs.acs.org pubs.acs.org
    Aptamer Reduces Aggregation of Mutant Huntingtin and Rescues Proteostasis Network in Non-Neuronal and Neuronal Cells
    2
    1. scibot 11 Jul 2023
      RRID AB_94263

      DOI: 10.1021/acschemneuro.3c00226

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      Curator: @jmitrevska

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    2. scibot 11 Jul 2023
      RRID:AB_94263

      DOI: 10.1021/acschemneuro.3c00226

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    pubs.acs.org/doi/10.1021/acschemneuro.3c00226
  12. May 2023
  13. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
    1
    1. scibot 05 May 2023
      RRID:AB_94263

      DOI: 10.1038/s41467-022-31905-0

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    nature.com/articles/s41467-022-31905-0
  14. Feb 2022
  15. www.sciencedirect.com www.sciencedirect.com
    Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice
    1
    1. scibot 04 Feb 2022
      RRID:AB_94263

      DOI: 10.1016/j.neuron.2022.01.006

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    sciencedirect.com/science/article/pii/S089662732200006X
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress
    1
    1. scibot 02 Feb 2022
      RRID:AB_94263

      DOI: 10.7554/eLife.72169

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    ncbi.nlm.nih.gov/pmc/articles/PMC8794470/
  17. Jul 2021
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 29 Jul 2021
      AB_94263

      DOI: 10.1016/j.celrep.2018.11.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6314484/
  19. May 2021
  20. www.sciencedirect.com www.sciencedirect.com
    Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
    1
    1. scibot 08 May 2021
      RRID:AB_94263

      DOI: 10.1016/j.neuron.2020.11.005

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    sciencedirect.com/science/article/pii/S0896627320308837
  21. Sep 2020
  22. www.sciencedirect.com www.sciencedirect.com
    DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
    1
    1. scibot 16 Sep 2020
      RRID:AB_94263

      DOI: 10.1016/j.molcel.2020.02.022

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      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:AB_94263
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    sciencedirect.com/science/article/pii/S1097276520301155
  23. elifesciences.org elifesciences.org
    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease
    1
    1. scibot 08 Sep 2020
      RRID:AB_94263

      DOI: 10.7554/eLife.51093

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      Curator: @Naa003

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    elifesciences.org/articles/51093
  24. Jan 2020
  25. www.sciencedirect.com www.sciencedirect.com
    Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line
    1
    1. scibot 13 Jan 2020
      RRID:AB_94263

      DOI: 10.1016/j.scr.2019.101504

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      Curator: @ethanbadger

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      RRID:AB_94263 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1873506119301345
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mutant Huntingtin Fails to Directly Impair Brain Mitochondria
    1
    1. scibot 13 Jan 2020
      RRID:AB_94263

      DOI: 10.1111/jnc.14852

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14852
  27. www.nature.com www.nature.com
    Assessing average somatic CAG repeat instability at the protein level
    1
    1. scibot 13 Jan 2020
      RRID:AB_94263

      DOI: 10.1038/s41598-019-55202-x

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      Curator: @evieth

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      RRID:AB_94263 RRIDCUR:Validated
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    nature.com/articles/s41598-019-55202-x
  28. www.sciencedirect.com www.sciencedirect.com
    Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy
    1
    1. scibot 13 Jan 2020
      RRID:AB_94263

      DOI: 10.1016/j.neuron.2019.12.003

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      Curator: @ethanbadger

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      RRID:AB_94263 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319310451
  29. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_94263

      DOI: 10.1016/j.celrep.2019.02.008

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719301706
  30. www.sciencedirect.com www.sciencedirect.com
    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity
    1
    1. scibot 13 Jan 2020
      AB_94263

      DOI: 10.1016/j.celrep.2018.11.019

      Resource: (Millipore Cat# MAB1574, RRID:AB_94263)

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      RRID:AB_94263 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718317650
  31. www.sciencedirect.com www.sciencedirect.com
    Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease
    1
    1. scibot 12 Jan 2020
      RRID:AB_94263

      DOI: 10.1016/j.celrep.2019.01.028

      Resource: (Millipore Cat# MAB1574, RRID:AB_94263)

      Curator: @ethanbadger

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      RRID:AB_94263 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719300373
  32. Nov 2018
  33. www.sciencedirect.com www.sciencedirect.com
    SRCP1 Conveys Resistance to Polyglutamine Aggregation
    1
    1. scibot 05 Nov 2018
      RRID:AB_94263

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      (Millipore Cat# MAB1574, RRID:AB_94263)

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    sciencedirect.com/science/article/pii/S1097276518305550
  34. www.sciencedirect.com www.sciencedirect.com
    Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration
    1
    1. scibot 05 Nov 2018
      RRID:AB_94263

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    sciencedirect.com/science/article/pii/S096098221731391X