60 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis
    1
    1. scibot 08 Nov 2024
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      DOI: 10.1016/j.lfs.2024.123200

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    sciencedirect.com/science/article/pii/S0024320524007902
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1158/1078-0432.CCR-24-1317

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443218/
  5. Sep 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1091/mbc.E23-09-0382

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    ncbi.nlm.nih.gov/pmc/articles/PMC11244170/
  7. www.sciencedirect.com www.sciencedirect.com
    Metformin decelerates aging clock in male monkeys
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.021

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    sciencedirect.com/science/article/pii/S0092867424009140
  8. Aug 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.ejmech.2024.116795

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    sciencedirect.com/science/article/pii/S0223523424006767
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
    1
    1. scibot 26 Aug 2024
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      DOI: 10.1101/2024.08.09.607311

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    ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
  11. www.cell.com www.cell.com
    Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway
    1
    1. scibot 13 Aug 2024
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      DOI: 10.1016/j.isci.2024.110075

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    cell.com/iscience/fulltext/S2589-0042(24)01300-2
  12. Jun 2024
  13. www.sciencedirect.com www.sciencedirect.com
    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114345

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    sciencedirect.com/science/article/pii/S2211124724006739
  14. www.cell.com www.cell.com
    Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway
    2
    1. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110075

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    2. scibot 14 Jun 2024
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      DOI: 10.1016/j.isci.2024.110075

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    cell.com/iscience/fulltext/S2589-0042(24)01300-2
  15. May 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The action mechanism by which C1q/tumor necrosis factor-related protein-6 alleviates cerebral ischemia/reperfusion injury in diabetic mice
    1
    1. scibot 01 May 2024
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      DOI: 10.4103/1673-5374.390951

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    ncbi.nlm.nih.gov/pmc/articles/PMC11040306/
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response
    2
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.chembiol.2023.12.005

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    2. scibot 11 Jan 2024
      RRID:AB_944418

      DOI: 10.1016/j.chembiol.2023.12.005

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    sciencedirect.com/science/article/pii/S245194562300435X
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1083/jcb.202304026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
  20. Dec 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1016/j.chembiol.2023.12.005

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    sciencedirect.com/science/article/pii/S245194562300435X
  22. www.sciencedirect.com www.sciencedirect.com
    Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101302

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    sciencedirect.com/science/article/pii/S2666379123004962
  23. Nov 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113437

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    sciencedirect.com/science/article/pii/S2211124723014493
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101224

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    sciencedirect.com/science/article/pii/S2666379123003981
  27. www.sciencedirect.com www.sciencedirect.com
    Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.redox.2023.102918

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    sciencedirect.com/science/article/pii/S2213231723003191
  28. Sep 2023
  29. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113104

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    sciencedirect.com/science/article/pii/S2211124723011154
  30. Aug 2023
  31. 52.53.155.43 52.53.155.43
    s41596-023-00861-4-html.html
    1
    1. scibot 17 Aug 2023
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      DOI: 10.1038/s41593-018-0175-4

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    52.53.155.43/8a097cc29245bd27fcbce4843d2d164fee9b0176/s41596-023-00861-4-html.html
  32. Jul 2023
  33. www.sciencedirect.com www.sciencedirect.com
    FOXA2 controls the anti-oxidant response in FH-deficient cells
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112751

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    sciencedirect.com/science/article/pii/S2211124723007623
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    The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112724

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    sciencedirect.com/science/article/pii/S2211124723007350
  35. May 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
  37. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.celrep.2022.111077

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    sciencedirect.com/science/article/pii/S2211124722008750
  38. Feb 2023
  39. www.sciencedirect.com www.sciencedirect.com
    NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
    1
    1. scibot 25 Feb 2023
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      DOI: 10.1016/j.cmet.2023.01.012

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    sciencedirect.com/science/article/pii/S1550413123000128
  40. www.sciencedirect.com www.sciencedirect.com
    Global profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target
    1
    1. scibot 10 Feb 2023
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      DOI: 10.1016/j.isci.2023.106080

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    sciencedirect.com/science/article/pii/S2589004223001578
  41. Jan 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma
    1
    1. scibot 28 Jan 2023
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      DOI: 10.1016/j.ccell.2022.12.004

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    sciencedirect.com/science/article/pii/S1535610822005906
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
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    1. scibot 18 Jan 2023
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      DOI: 10.4103/1673-5374.355978

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 14 Jan 2023
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      DOI: 10.1111/bph.15993

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15993
  45. Oct 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
    1
    1. scibot 20 Oct 2022
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      DOI: 10.1016/j.cmet.2022.09.021

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    sciencedirect.com/science/article/pii/S1550413122004119
  47. Jul 2022
  48. link.springer.com link.springer.com
    Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction
    1
    1. scibot 15 Jul 2022
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      DOI: 10.1186/s13058-022-01548-6

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    link.springer.com/article/10.1186/s13058-022-01548-6
  49. Jun 2022
  50. academic.oup.com academic.oup.com
    NRF2 Serves A Critical Role In Regulation Of Immune Checkpoint Proteins (ICPs) During Trophoblast Differentiation
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      DOI: 10.1210/endocr/bqac070

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    academic.oup.com/endo/article/163/7/bqac070/6590287
  51. May 2022
  52. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  53. Apr 2022
  54. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15834

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15834
  55. www.sciencedirect.com www.sciencedirect.com
    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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      DOI: 10.1016/j.stem.2022.03.003

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    sciencedirect.com/science/article/pii/S1934590922001011
  56. Jan 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
    1
    1. scibot 05 Jan 2022
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      DOI: 10.1126/sciadv.abl4988

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    ncbi.nlm.nih.gov/pmc/articles/PMC8673768/
  58. Dec 2021
  59. www.science.org www.science.org
    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
    1
    1. scibot 31 Dec 2021
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      DOI: 10.1126/sciadv.abl4988

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    science.org/doi/abs/10.1126/sciadv.abl4988
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    USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1
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      DOI: 10.1016/j.celrep.2021.110174

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    sciencedirect.com/science/article/pii/S2211124721016740
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    Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation
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      DOI: 10.1016/j.devcel.2021.11.009

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    sciencedirect.com/science/article/pii/S1534580721008947
  62. Oct 2021
  63. www.sciencedirect.com www.sciencedirect.com
    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
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    1. scibot 21 Oct 2021
      AB_944418

      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
  64. Aug 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion
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      RRID:AB_944418

      DOI: 10.1016/j.devcel.2018.10.026

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    sciencedirect.com/science/article/pii/S1534580718308803
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jnr.24096

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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24096
  67. Jul 2021
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jnr.24357

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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24357
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    mfat‐1 transgene protects cultured adult neural stem cells against cobalt chloride–mediated hypoxic injury by activating Nrf2/ARE pathways
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      DOI: 10.1002/jnr.24096

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24096/full
  70. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways
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    1. scibot 27 Jul 2021
      RRID:AB_944418RRID:AB_944418

      DOI: 10.1111/bph.14592

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  71. www.sciencedirect.com www.sciencedirect.com
    Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin
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      DOI: 10.1016/j.ebiom.2021.103456

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    sciencedirect.com/science/article/pii/S2352396421002498
  72. May 2021
  73. journals.plos.org journals.plos.org
    The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
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      either

      DOI: 10.1371/journal.ppat.1009422

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    journals.plos.org/plospathogens/article
  74. Apr 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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    1. scibot 22 Apr 2021
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      DOI: 10.1016/j.ccell.2021.02.016

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    sciencedirect.com/science/article/pii/S1535610821001185
  76. Feb 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury
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      DOI: 10.1111/jcmm.14935

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    onlinelibrary.wiley.com/doi/10.1111/jcmm.14935
  78. Dec 2020
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mulberroside A repairs high fructose diet‐induced damage of intestinal epithelial and blood–brain barriers in mice: A potential for preventing hippocampal neuroinflammatory injury
    1
    1. scibot 07 Dec 2020
      RRID:AB_944418

      DOI: 10.1111/jnc.15242

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15242
  80. Sep 2020
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response
    1
    1. scibot 17 Sep 2020
      RRID:AB_944418

      DOI: 10.7554/eLife.54877

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  82. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_944418

      DOI: 10.1111/bph.15080

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
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    1. scibot 09 Sep 2020
      RRID:AB_944418

      DOI: 10.7554/eLife.59994

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    ncbi.nlm.nih.gov/pmc/articles/PMC7462607/
  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
    1
    1. scibot 13 Jan 2020
      RRID:AB_944418

      DOI: 10.1016/j.devcel.2019.07.010

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    sciencedirect.com/science/article/pii/S1534580719305829
  86. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_944418

      DOI: 10.1016/j.ccell.2018.12.009

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    sciencedirect.com/science/article/pii/S1535610818305816
  87. Nov 2018
  88. www.sciencedirect.com www.sciencedirect.com
    The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
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      RRID:AB_944418

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    sciencedirect.com/science/article/pii/S1550413118303905
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice
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    1. scibot 05 Nov 2018
      RRID:AB_944418

      Curator: @anp055

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    onlinelibrary.wiley.com/doi/full/10.1002/brb3.1024
  90. www.sciencedirect.com www.sciencedirect.com
    NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression
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    1. scibot 05 Nov 2018
      RRID:AB_944418

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    sciencedirect.com/science/article/pii/S1097276517306573
  91. Nov 2017
  92. www.sciencedirect.com www.sciencedirect.com
    Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
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    1. scibot 08 Nov 2017
      RRID:AB_944418

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417310474