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Disrupting mitochondrial dynamics attenuates ferroptosis and chemotoxicity via upregulating NRF2-mediated FSP1 expression

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116234
  
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sciencedirect.com/science/article/pii/S2211124725010058
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Temporal analysis of doxorubicin-induced cardiac toxicity and hypertrophy

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1. scibot 04 Jul 2025
  
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  DOI: 10.1038/s41540-025-00545-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12219892/
Jun 2025
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Dual Role of NRF2 in Pancreatic Precursor Lesions

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1. scibot 13 Jun 2025
  
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  DOI: 10.1158/2767-9764.CRC-25-0107
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12158068/
May 2025
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Dysregulation of Labile Iron Predisposes Chemotherapy Resistant Cancer Cells to Ferroptosis

1
1. scibot 21 May 2025
  
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  DOI: 10.3390/ijms26094193
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12072162/
Apr 2025
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β-Cell Dedifferentiation in HOMA-βlow and HOMA-βhigh Subjects

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1. scibot 24 Apr 2025
  
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  DOI: 10.1210/clinem/dgae538
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12012814/
Feb 2025
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

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1. scibot 27 Feb 2025
  
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  DOI: 10.1038/s44319-024-00361-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
Jan 2025
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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.neuron.2024.12.016
  
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sciencedirect.com/science/article/pii/S0896627324009152
Nov 2024
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Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis

1
1. scibot 08 Nov 2024
  
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  DOI: 10.1016/j.lfs.2024.123200
  
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sciencedirect.com/science/article/pii/S0024320524007902
Oct 2024
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Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis

1
1. scibot 04 Oct 2024
  
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  DOI: 10.1158/1078-0432.CCR-24-1317
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443218/
Sep 2024
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Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

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1. scibot 26 Sep 2024
  
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  AB_944418
  
  DOI: 10.1091/mbc.E23-09-0382
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11244170/
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Metformin decelerates aging clock in male monkeys

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1. scibot 13 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.021
  
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sciencedirect.com/science/article/pii/S0092867424009140
Aug 2024
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Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.ejmech.2024.116795
  
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sciencedirect.com/science/article/pii/S0223523424006767
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TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma

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1. scibot 26 Aug 2024
  
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  AB_944418
  
  DOI: 10.1101/2024.08.09.607311
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
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Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway

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1. scibot 13 Aug 2024
  
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  RRID: AB_944418
  
  DOI: 10.1016/j.isci.2024.110075
  
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cell.com/iscience/fulltext/S2589-0042(24)01300-2
Jun 2024
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CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114345
  
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sciencedirect.com/science/article/pii/S2211124724006739
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Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway

2
1. scibot 14 Jun 2024
  
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  RRID: AB_944418
  
  DOI: 10.1016/j.isci.2024.110075
  
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2. scibot 14 Jun 2024
  
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  RRID:AB_944418
  
  DOI: 10.1016/j.isci.2024.110075
  
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cell.com/iscience/fulltext/S2589-0042(24)01300-2
May 2024
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The action mechanism by which C1q/tumor necrosis factor-related protein-6 alleviates cerebral ischemia/reperfusion injury in diabetic mice

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1. scibot 01 May 2024
  
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  DOI: 10.4103/1673-5374.390951
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11040306/
Jan 2024
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Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

2
1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.chembiol.2023.12.005
  
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2. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.chembiol.2023.12.005
  
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sciencedirect.com/science/article/pii/S245194562300435X
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A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope

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1. scibot 05 Jan 2024
  
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  DOI: 10.1083/jcb.202304026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
Dec 2023
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Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.chembiol.2023.12.005
  
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sciencedirect.com/science/article/pii/S245194562300435X
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Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101302
  
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sciencedirect.com/science/article/pii/S2666379123004962
Nov 2023
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Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113437
  
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sciencedirect.com/science/article/pii/S2211124723014493
Oct 2023
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Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101224
  
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sciencedirect.com/science/article/pii/S2666379123003981
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Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.redox.2023.102918
  
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sciencedirect.com/science/article/pii/S2213231723003191
Sep 2023
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A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants

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1. scibot 14 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113104
  
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sciencedirect.com/science/article/pii/S2211124723011154
Aug 2023
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s41596-023-00861-4-html.html

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1. scibot 17 Aug 2023
  
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  DOI: 10.1038/s41593-018-0175-4
  
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52.53.155.43/8a097cc29245bd27fcbce4843d2d164fee9b0176/s41596-023-00861-4-html.html
Jul 2023
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FOXA2 controls the anti-oxidant response in FH-deficient cells

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1. scibot 07 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112751
  
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sciencedirect.com/science/article/pii/S2211124723007623
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The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2

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1. scibot 07 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112724
  
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sciencedirect.com/science/article/pii/S2211124723007350
May 2023
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Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells

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1. scibot 27 May 2023
  
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  DOI: 10.1016/j.isci.2023.106827
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.celrep.2022.111077
  
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sciencedirect.com/science/article/pii/S2211124722008750
Feb 2023
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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer

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1. scibot 25 Feb 2023
  
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  DOI: 10.1016/j.cmet.2023.01.012
  
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sciencedirect.com/science/article/pii/S1550413123000128
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Global profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target

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1. scibot 10 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106080
  
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sciencedirect.com/science/article/pii/S2589004223001578
Jan 2023
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Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma

1
1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.ccell.2022.12.004
  
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sciencedirect.com/science/article/pii/S1535610822005906
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Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

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1. scibot 18 Jan 2023
  
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  DOI: 10.1111/bph.15993
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15993
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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

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Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction

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NRF2 Serves A Critical Role In Regulation Of Immune Checkpoint Proteins (ICPs) During Trophoblast Differentiation

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Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

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Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease

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Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance

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Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance

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USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1

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Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation

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NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression

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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

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Untitled document

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mfat‐1 transgene protects cultured adult neural stem cells against cobalt chloride–mediated hypoxic injury by activating Nrf2/ARE pathways

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Aspirin eugenol ester attenuates oxidative injury of vascular endothelial cells by regulating NOS and Nrf2 signalling pathways

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Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

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The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism

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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

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Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury

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  DOI: 10.1111/jcmm.14935
  
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onlinelibrary.wiley.com/doi/10.1111/jcmm.14935
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Mulberroside A repairs high fructose diet‐induced damage of intestinal epithelial and blood–brain barriers in mice: A potential for preventing hippocampal neuroinflammatory injury

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onlinelibrary.wiley.com/doi/10.1111/jnc.15242
Sep 2020
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Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

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  DOI: 10.1111/bph.15080
  
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Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation

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ncbi.nlm.nih.gov/pmc/articles/PMC7462607/
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Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

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Untitled document

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The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

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Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice

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NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

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sciencedirect.com/science/article/pii/S1097276517306573
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Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

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sciencedirect.com/science/article/pii/S0092867417310474

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