88 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
    1
    1. scibot 23 Aug 2024
      AB_945626

      DOI: 10.1016/j.molcel.2024.08.006

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    sciencedirect.com/science/article/pii/S1097276524006609
  3. www.mdpi.com www.mdpi.com
    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
    1
    1. scibot 02 Aug 2024
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      DOI: 10.3390/ijms222413398

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    mdpi.com/1422-0067/22/24/13398/htm
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
    2
    1. scibot 02 Aug 2024
      AB_945626

      DOI: 10.1002/jnr.23910

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    2. scibot 02 Aug 2024
      AB_945626

      DOI: 10.1002/jnr.23910

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    onlinelibrary.wiley.com/doi/10.1002/jnr.23910/full
  5. Jul 2024
  6. www.cell.com www.cell.com
    Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance
    1
    1. scibot 18 Jul 2024
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2024.114409

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    cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 17 Jul 2024
      AB_945626

      DOI: 10.12688/f1000research.132628.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11240082/
  8. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
    1
    1. scibot 04 Jul 2024
      RRID:AB_945626

      DOI: 10.7554/eLife.98649

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    elifesciences.org/articles/98649
  9. Jun 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts
    1
    1. scibot 21 Jun 2024
      RRID:AB_945626

      DOI: 10.1016/j.devcel.2024.05.011

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    sciencedirect.com/science/article/pii/S1534580724003289
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
    1
    1. scibot 13 Jun 2024
      RRID:AB_945626

      DOI: 10.1038/s41467-024-49196-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161513/
  12. May 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females
    1
    1. scibot 30 May 2024
      RRID: AB_945626

      DOI: 10.1016/j.celrep.2024.114293

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    sciencedirect.com/science/article/pii/S2211124724006211
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
    1
    1. scibot 25 May 2024
      RRID:AB_945626

      DOI: 10.1038/s41598-024-60602-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11111795/
  15. Apr 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
    2
    1. scibot 09 Apr 2024
      AB_945626

      DOI: 10.1016/j.xcrm.2024.101503

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    2. scibot 09 Apr 2024
      AB_945626

      DOI: 10.1016/j.xcrm.2024.101503

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    sciencedirect.com/science/article/pii/S2666379124001721
  17. Feb 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis
    1
    1. scibot 08 Feb 2024
      RRID:AB_945626

      DOI: 10.1016/j.isci.2024.108883

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838789/
  19. Dec 2023
  20. www.sciencedirect.com www.sciencedirect.com
    D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder
    1
    1. scibot 16 Dec 2023
      RRID:AB_945626

      DOI: 10.1016/j.devcel.2023.11.017

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    sciencedirect.com/science/article/pii/S1534580723006159
  21. www.sciencedirect.com www.sciencedirect.com
    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
    1
    1. scibot 07 Dec 2023
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2023.113529

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    sciencedirect.com/science/article/pii/S2211124723015413
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy
    1
    1. scibot 02 Nov 2023
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2023.113342

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    sciencedirect.com/science/article/pii/S2211124723013542
  24. Oct 2023
  25. www.sciencedirect.com www.sciencedirect.com
    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
    1
    1. scibot 06 Oct 2023
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2023.113183

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    sciencedirect.com/science/article/pii/S2211124723011956
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Designer Drug αPHP Affected Cell Proliferation and Triggered Deathly Mechanisms in Murine Neural Stem/Progenitor Cells
    1
    1. scibot 06 Oct 2023
      RRID:AB_945626

      DOI: 10.3390/biology12091225

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    ncbi.nlm.nih.gov/pmc/articles/PMC10525791/
  27. Sep 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
    1
    1. scibot 08 Sep 2023
      RRID:AB_945626

      DOI: 10.1016/j.molcel.2023.08.005

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    sciencedirect.com/science/article/pii/S109727652300641X
  29. Aug 2023
  30. www.sciencedirect.com www.sciencedirect.com
    RhoB Promotes Salmonella survival by Regulating Autophagy
    1
    1. scibot 31 Aug 2023
      RRID:AB_945626

      DOI: 10.1016/j.ejcb.2023.151358

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    sciencedirect.com/science/article/pii/S0171933523000730
  31. www.sciencedirect.com www.sciencedirect.com
    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
    1
    1. scibot 27 Aug 2023
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2023.113045

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    sciencedirect.com/science/article/pii/S2211124723010562
  32. Jul 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bexarotene improves motor function after spinal cord injury in mice
    1
    1. scibot 22 Jul 2023
      RRID:AB_945626

      DOI: 10.4103/1673-5374.373676

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    ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
  34. Jun 2023
  35. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial iron-responsive pathway regulated by DELE1
    1
    1. scibot 21 Jun 2023
      RRID:AB_945626

      DOI: 10.1016/j.molcel.2023.05.031

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    sciencedirect.com/science/article/pii/S1097276523004136
  36. 52.53.155.43 52.53.155.43
    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
    1
    1. scibot 15 Jun 2023
      AB_945626

      DOI: 10.12688/f1000research.132628.1

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    52.53.155.43/9bb0847614ccded1b0f58470978ac3d19ed6d9f2/c2b09516-8ba1-4604-955c-4ba2339bb68f_132628_-_kathleen_southern-html.html
  37. Apr 2023
  38. www.biorxiv.org www.biorxiv.org
    RhoB promotes Salmonella survival by regulating autophagy
    1
    1. scibot 20 Apr 2023
      RRID:AB_945626

      DOI: 10.1101/2023.04.05.535690

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    biorxiv.org/content/10.1101/2023.04.05.535690v1
  39. www.sciencedirect.com www.sciencedirect.com
    Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation
    1
    1. scibot 19 Apr 2023
      RRID:AB_945626

      DOI: 10.1016/j.cmet.2023.03.019

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    sciencedirect.com/science/article/pii/S1550413123001249
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determination of the autophagic flux in murine and human peripheral blood mononuclear cells
    1
    1. scibot 04 Apr 2023
      RRID:AB_945626

      DOI: 10.3389/fcell.2023.1122998

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    ncbi.nlm.nih.gov/pmc/articles/PMC10040559/
  41. Jan 2023
  42. www.sciencedirect.com www.sciencedirect.com
    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
    1
    1. scibot 27 Jan 2023
      AB_945626

      DOI: 10.1016/j.celrep.2023.112037

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    sciencedirect.com/science/article/pii/S2211124723000487
  43. www.sciencedirect.com www.sciencedirect.com
    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration
    1
    1. scibot 26 Jan 2023
      RRID:AB_945626

      DOI: 10.1016/j.celrep.2023.112025

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    sciencedirect.com/science/article/pii/S2211124723000360
  44. Dec 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
    1
    1. scibot 01 Dec 2022
      RRID:AB_945626

      DOI: 10.3389/fncel.2022.1021592

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    ncbi.nlm.nih.gov/pmc/articles/PMC9684630/
  46. Oct 2022
  47. www.nature.com www.nature.com
    C9orf72 functions in the nucleus to regulate DNA damage repair
    1
    1. scibot 12 Oct 2022
      RRID:AB_945626

      DOI: 10.1038/s41418-022-01074-0

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    nature.com/articles/s41418-022-01074-0
  48. Sep 2022
  49. www.tandfonline.com www.tandfonline.com
    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
    1
    1. scibot 16 Sep 2022
      RRID:AB_945626

      DOI: 10.1080/15548627.2022.2100105

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    tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
  50. May 2022
  51. aacrjournals.org aacrjournals.org
    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
    1
    1. scibot 10 May 2022
      AB_945626

      DOI: 10.1158/2767-9764.CRC-22-0037

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    aacrjournals.org/cancerrescommun/article/2/5/293/696275/Repurposing-Itraconazole-and-Hydroxychloroquine-to
  52. Apr 2022
  53. www.sciencedirect.com www.sciencedirect.com
    CCT2 is an aggrephagy receptor for clearance of solid protein aggregates
    1
    1. scibot 07 Apr 2022
      RRID:AB_945626

      DOI: 10.1016/j.cell.2022.03.005

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    sciencedirect.com/science/article/pii/S0092867422002653
  54. Jan 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism
    1
    1. scibot 19 Jan 2022
      RRID:AB_945626

      DOI: 10.1016/j.xcrm.2021.100498

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    sciencedirect.com/science/article/pii/S266637912100375X
  56. www.sciencedirect.com www.sciencedirect.com
    Mosaic dysfunction of mitophagy in mitochondrial muscle disease
    1
    1. scibot 14 Jan 2022
      RRID:AB_945626

      DOI: 10.1016/j.cmet.2021.12.017

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    sciencedirect.com/science/article/pii/S1550413121006367
  57. Dec 2021
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 21 Dec 2021
      RRID:AB_945626

      DOI: 10.1111/bph.15702

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15702
  59. Nov 2021
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic lithium administration in a mouse model for Krabbe disease
    1
    1. scibot 13 Nov 2021
      ab56416

      DOI: 10.1002/jmd2.12258

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    onlinelibrary.wiley.com/doi/10.1002/jmd2.12258
  61. Sep 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
    1
    1. scibot 18 Sep 2021
      RRID:AB_945626

      DOI: 10.7150/thno.59728

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    ncbi.nlm.nih.gov/pmc/articles/PMC8419049/
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
    1
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  64. www.sciencedirect.com www.sciencedirect.com
    Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
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  65. Aug 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability
    1
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      DOI: 10.1038/s41467-021-24713-5

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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Immunodeficiency Virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia
    1
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      DOI: 10.1002/glia.23568

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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasma Rich in Growth Factors Promotes Autophagy in ARPE19 Cells in Response to Oxidative Stress Induced by Blue Light
    1
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      DOI: 10.3390/biom11070954

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  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
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  73. Jul 2021
  74. academic.oup.com academic.oup.com
    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
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  75. www.mdpi.com www.mdpi.com
    Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1
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  76. elifesciences.org elifesciences.org
    Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS
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  77. www.nature.com www.nature.com
    Degradation of lipid droplets by chimeric autophagy-tethering compounds
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  78. Jun 2021
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    Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease
    2
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      DOI: 10.1080/15548627.2020.1760014

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  80. May 2021
  81. link.springer.com link.springer.com
    In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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      DOI: 10.1186/s40478-021-01200-y

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  82. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.15399

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of neuronal α-Synuclein inclusions
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  84. Feb 2021
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12
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      DOI: 10.1038/s41419-020-2266-x

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  86. Jan 2021
  87. link.springer.com link.springer.com
    Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model
    1
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      anti-p62

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  88. Nov 2020
  89. www.sciencedirect.com www.sciencedirect.com
    The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina
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  90. Oct 2020
  91. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects
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  92. Sep 2020
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD4+ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy
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      DOI: 10.1128/mBio.00903-20

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  94. www.nature.com www.nature.com
    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling
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      DOI: 10.1038/s41419-020-02805-2

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  95. www.jbc.org www.jbc.org
    The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein
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      DOI: 10.1074/jbc.RA120.013337

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  96. insight.jci.org insight.jci.org
    The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP
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      sequestosome 1

      DOI: 10.1172/jci.insight.132364

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  97. www.sciencedirect.com www.sciencedirect.com
    The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice
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      DOI: 10.1016/j.neuron.2020.03.005

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  98. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      anti‐mouse

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  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
    1
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      RRID:AB_945626

      DOI: 10.1016/j.celrep.2019.09.029

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons
    1
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      DOI: 10.7554/eLife.44423

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  102. www.sciencedirect.com www.sciencedirect.com
    The N-Degron Pathway Mediates ER-phagy
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      DOI: 10.1016/j.molcel.2019.06.028

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  103. elifesciences.org elifesciences.org
    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
    1
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      RRID:AB_945626

      DOI: 10.7554/eLife.44219

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  104. www.sciencedirect.com www.sciencedirect.com
    Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy
    1
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      DOI: 10.1016/j.neuron.2019.12.003

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology
    1
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      DOI: 10.7554/eLife.39578

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  106. www.jneurosci.org www.jneurosci.org
    Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury
    1
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      RRID:AB_945626

      DOI: 10.1523/JNEUROSCI.3415-17.2018

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  108. Nov 2018
  109. www.sciencedirect.com www.sciencedirect.com
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  110. www.sciencedirect.com www.sciencedirect.com
    Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
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  111. www.ecancer.org www.ecancer.org
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lasting pathologic complete response to chemotherapy for ovarian cancer after receiving antimalarials for dermatomyositis
    1
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  119. Nov 2017
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