36 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
    1
    1. scibot 11 Nov 2024
      RRID:AB_956386

      DOI: 10.1016/j.stem.2024.10.007

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    sciencedirect.com/science/article/pii/S1934590924003692
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids
    1
    1. scibot 11 Sep 2024
      RRID:AB_956386

      DOI: 10.1016/j.stem.2024.08.008

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    sciencedirect.com/science/article/pii/S1934590924002947
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Multi-omic analysis reveals VEGFR2, PI3K, and JNK mediate small molecule induction of human iPSC-derived cardiomyocyte proliferation
    1
    1. scibot 21 Aug 2024
      AB_956386

      DOI: 10.1016/j.isci.2024.110485

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    sciencedirect.com/science/article/pii/S2589004224017103
  7. Jul 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Transient titin-dependent ventricular defects during development lead to adult atrial arrhythmia and impaired contractility
    1
    1. scibot 23 Jul 2024
      AB_956386

      DOI: 10.1016/j.isci.2024.110395

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    sciencedirect.com/science/article/pii/S2589004224016201
  9. Jun 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue
    1
    1. scibot 04 Jun 2024
      RRID:AB_956386

      DOI: 10.1016/j.celrep.2024.114302

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    sciencedirect.com/science/article/pii/S2211124724006302
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Generation of CRISPR/Cas9 edited human induced pluripotent stem cell line carrying the heterozygous p.H695VfsX5 frameshift mutation in the exon 10 of the PKP2 gene
    1
    1. scibot 15 Feb 2024
      RRID:AB_956386

      DOI: 10.1016/j.scr.2024.103341

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    sciencedirect.com/science/article/pii/S1873506124000394
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells
    1
    1. scibot 29 Dec 2023
      RRID:AB_956386

      DOI: 10.1016/j.scr.2023.103295

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    sciencedirect.com/science/article/pii/S1873506123002817
  15. www.sciencedirect.com www.sciencedirect.com
    Scalable production of homogeneous cardiac organoids derived from human pluripotent stem cells
    1
    1. scibot 23 Dec 2023
      RRID:AB_956386

      DOI: 10.1016/j.crmeth.2023.100666

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    sciencedirect.com/science/article/pii/S2667237523003454
  16. www.sciencedirect.com www.sciencedirect.com
    Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing
    1
    1. scibot 14 Dec 2023
      RRID:AB_956386

      DOI: 10.1016/j.scr.2023.103276

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    sciencedirect.com/science/article/pii/S1873506123002623
  17. www.sciencedirect.com www.sciencedirect.com
    Multi-chamber cardioids unravel human heart development and cardiac defects
    1
    1. scibot 02 Dec 2023
      RRID:AB_956386

      DOI: 10.1016/j.cell.2023.10.030

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    sciencedirect.com/science/article/pii/S0092867423011819
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Efficient exon skipping by base-editor-mediated abrogation of exonic splicing enhancers
    1
    1. scibot 02 Nov 2023
      RRID:AB_956386

      DOI: 10.1016/j.celrep.2023.113340

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    sciencedirect.com/science/article/pii/S2211124723013529
  20. Jul 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Generation of vascularized human cardiac organoids for 3D in vitro modeling
    1
    1. scibot 05 Jul 2023
      RRID:AB_956386

      DOI: 10.1016/j.xpro.2023.102371

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    sciencedirect.com/science/article/pii/S2666166723003386
  22. Apr 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Vascular cells improve functionality of human cardiac organoids
    1
    1. scibot 27 Apr 2023
      RRID:AB_956386

      DOI: 10.1016/j.celrep.2023.112322

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    sciencedirect.com/science/article/pii/S2211124723003339
  24. www.sciencedirect.com www.sciencedirect.com
    Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy
    1
    1. scibot 07 Apr 2023
      RRID:AB_956386

      DOI: 10.1016/j.stem.2023.03.010

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    sciencedirect.com/science/article/pii/S1934590923000814
  25. Nov 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros
    1
    1. scibot 18 Nov 2022
      RRID:AB_956386

      DOI: 10.1016/j.isci.2022.105414

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    ncbi.nlm.nih.gov/pmc/articles/PMC9646950/
  27. Sep 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome
    1
    1. scibot 27 Sep 2022
      RRID:AB_956386

      DOI: 10.1016/j.cels.2022.09.001

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    sciencedirect.com/science/article/pii/S2405471222003532
  29. Mar 2022
  30. www.sciencedirect.com www.sciencedirect.com
    PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem-cell-derived cardiomyocytes
    1
    1. scibot 27 Mar 2022
      RRID:AB_956386

      DOI: 10.1016/j.stem.2022.02.011

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    sciencedirect.com/science/article/pii/S1934590922000972
  31. Jan 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation
    1
    1. scibot 22 Jan 2022
      RRID:AB_956386

      DOI: 10.7554/eLife.60311

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    ncbi.nlm.nih.gov/pmc/articles/PMC8763402/
  33. www.sciencedirect.com www.sciencedirect.com
    Generation of SCN5A heterozygous knock-out human induced pluripotent stem cell line by CRISPR/Cas9-mediated genome editing
    1
    1. scibot 21 Jan 2022
      AB_956386

      DOI: 10.1016/j.scr.2022.102680

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    sciencedirect.com/science/article/pii/S1873506122000290
  34. Dec 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids
    1
    1. scibot 03 Dec 2021
      RRID:AB_956386

      DOI: 10.1016/j.stem.2021.11.007

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    sciencedirect.com/science/article/pii/S1934590921004550
  36. Sep 2021
  37. www.sciencedirect.com www.sciencedirect.com
    RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
    1
    1. scibot 16 Sep 2021
      RRID:AB_956386

      DOI: 10.1016/j.stem.2021.08.006

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    sciencedirect.com/science/article/pii/S193459092100343X
  38. Aug 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation
    1
    1. scibot 27 Aug 2021
      RRID:AB_956386

      DOI: 10.1016/j.scr.2021.102518

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    sciencedirect.com/science/article/pii/S1873506121003652
  40. www.sciencedirect.com www.sciencedirect.com
    Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro
    1
    1. scibot 06 Aug 2021
      RRID:AB_956386

      DOI: 10.1016/j.cels.2021.07.003

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    sciencedirect.com/science/article/pii/S2405471221002817
  41. Jul 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression
    1
    1. scibot 28 Jul 2021
      RRID:AB_956386

      DOI: 10.1016/j.scr.2021.102473

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    sciencedirect.com/science/article/pii/S1873506121003202
  43. www.sciencedirect.com www.sciencedirect.com
    A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles
    1
    1. scibot 27 Jul 2021
      RRID:AB_956386

      DOI: 10.1016/j.stem.2019.02.015

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    sciencedirect.com/science/article/pii/S1934590919300670
  44. Jun 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation
    1
    1. scibot 08 Jun 2021
      RRID:AB_956386

      DOI: 10.1016/j.scr.2021.102418

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    sciencedirect.com/science/article/pii/S1873506121002646
  46. May 2021
  47. www.cell.com www.cell.com
    Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes
    1
    1. scibot 27 May 2021
      RRID:AB_956386

      DOI: 10.1016/j.cels.2021.05.001

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    cell.com/cell-systems/fulltext/S2405-4712(21)00156-3
  48. www.sciencedirect.com www.sciencedirect.com
    Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome
    1
    1. scibot 09 May 2021
      RRID:AB_956386

      DOI: 10.1016/j.stem.2020.07.015

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    sciencedirect.com/science/article/pii/S1934590920303532
  49. www.sciencedirect.com www.sciencedirect.com
    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
    1
    1. scibot 05 May 2021
      RRID:AB_956386

      DOI: 10.1016/j.devcel.2020.07.006

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    sciencedirect.com/science/article/pii/S1534580720305803
  50. Apr 2021
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
    1
    1. scibot 06 Apr 2021
      RRID:AB_956386

      DOI: 10.1016/j.cell.2021.03.026

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    ncbi.nlm.nih.gov/pmc/articles/PMC7962543/
  52. Feb 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human iPSC-Derived Cardiomyocytes , are Susceptible to SARS-CoV-2 Infection
    1
    1. scibot 26 Feb 2021
      RRID:AB_956386

      DOI: 10.1016/j.xcrm.2020.100052

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    ncbi.nlm.nih.gov/pmc/articles/PMC7323681/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    1
    1. scibot 12 Feb 2021
      RRID:AB_956386

      DOI: 10.3389/fphar.2020.553852

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    ncbi.nlm.nih.gov/pmc/articles/PMC7874215/
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation
    1
    1. scibot 26 Sep 2020
      RRID:AB_956386

      DOI: 10.1016/j.scr.2020.101944

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    sciencedirect.com/science/article/pii/S1873506120302452
  57. www.sciencedirect.com www.sciencedirect.com
    Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    1
    1. scibot 11 Sep 2020
      RRID:AB_956386

      DOI: 10.1016/j.celrep.2020.107886

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    sciencedirect.com/science/article/pii/S2211124720308676
  58. Nov 2018
  59. www.sciencedirect.com www.sciencedirect.com
    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
    1
    1. scibot 05 Nov 2018
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S109727651830741X
  60. www.sciencedirect.com www.sciencedirect.com
    SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1934590918300675