20 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comprehensive functional atlas of ALK kinase domain variants reveals resistance landscape to ALK inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12958575/
  3. Feb 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol for non-invasive delivery of CRISPR RNPs via virus-like particles for mouse model generation
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    sciencedirect.com/science/article/pii/S2666166726000055
  5. Nov 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509411/
  7. Sep 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas9
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    pmc.ncbi.nlm.nih.gov/articles/PMC12410342/
  9. Aug 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325647/
  11. Jul 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12204706/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-promoting UBR4 coordinates impaired mitophagy–associated senescence and lung adenocarcinoma pathogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12207436/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Establishment and rescue of fibroblast cell lines carrying a nonsense mutation of RB1 by CRISPR-based base editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12254293/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of heterozygous SMG1 mutations on nonsense-mediated mRNA decay in human pluripotent stem cell model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12173119/
  16. Jun 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Functional assessment of all ATM SNVs using prime editing and deep learning
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    sciencedirect.com/science/article/pii/S0092867425006348
  18. May 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy induction enhances homologous recombination-associated CRISPR–Cas9 gene editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997770/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An innovative approach using CRISPR-ribonucleoprotein packaged in virus-like particles to generate genetically engineered mouse models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11992299/
  21. Apr 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK activation by glycogen expenditure primes the exit of naïve pluripotency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11933299/
  23. Aug 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Guide for generating single-cell–derived knockout clones in mammalian cell lines using the CRISPR/Cas9 system
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292505/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early Developmental Characteristics and Features of a Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311801/
  26. Feb 2024
  27. www.biorxiv.org www.biorxiv.org
    Saturation resistance profiling of EGFR variants against tyrosine kinase inhibitors using prime editing
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    biorxiv.org/content/10.1101/2023.12.03.569825v1
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly efficient genome editing via CRISPR-Cas9 ribonucleoprotein (RNP) delivery in mesenchymal stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10828435/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide in-locus epitope tagging of Arabidopsis proteins using prime editors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10828436/
  30. Sep 2023
  31. www.nature.com www.nature.com
    CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
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    nature.com/articles/s42003-023-05052-1
  32. May 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease
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    sciencedirect.com/science/article/pii/S1934590921001673