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Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers

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1. scibot 23 Nov 2025
  
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  104991
  
  DOI: 10.1038/s41467-025-63349-7
  
  Resource: RRID:Addgene_104991
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12475092/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer

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1. scibot 23 Nov 2025
  
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  RRID:Addgene_104991
  
  DOI: 10.1261/rna.080637.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genome-wide screen in Mycobacterium tuberculosis infected macrophages reveals innate regulation of antibacterial mediators by IRF2

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1. scibot 21 Nov 2025
  
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  104991
  
  DOI: 10.1101/2025.09.26.678671
  
  Resource: RRID:Addgene_104991
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12621954/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ALKBH1 drives tumorigenesis and drug resistance via tRNA decoding reprogramming and codon-biased translation

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1. scibot 07 Sep 2025
  
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  104991
  
  DOI: 10.1158/2159-8290.CD-24-1043
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12377461/
Aug 2025
www.biorxiv.org www.biorxiv.org

ZYS-1 is not an ADAR1 inhibitor

1
1. scibot 13 Aug 2025
  
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  RRID:Addgene_104991
  
  DOI: 10.1101/2025.08.08.669362
  
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biorxiv.org/content/10.1101/2025.08.08.669362v2
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A side-by-side comparison of variant function measurements using deep mutational scanning and base editing

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1. scibot 11 Aug 2025
  
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  Addgene_104991
  
  DOI: 10.1093/nar/gkaf738
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12311789/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The role of gene duplication and paralog specialisation in the evolution of the mammalian PRPS complex

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1. scibot 20 Jul 2025
  
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  Addgene_104991
  
  DOI: 10.1038/s41467-025-61216-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12238573/
52.53.155.43 52.53.155.43

2025.07.10.663086v1.full-html.html

1
1. scibot 19 Jul 2025
  
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  plasmid_104991
  
  DOI: 10.1101/2025.07.10.663086
  
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52.53.155.43/c02a5ad83b4723258fb8c8a97f9d93911257fcd4/2025.07.10.663086v1.full-html.html
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism

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1. scibot 26 Aug 2024
  
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  Addgene_104991
  
  DOI: 10.1101/2024.08.06.606693
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11326184/
www.science.org www.science.org

The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma

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1. scibot 02 Aug 2024
  
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  RRID:Addgene_104991
  
  DOI: 10.1126/sciadv.adm9449
  
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science.org/doi/10.1126/sciadv.adm9449
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

History of tuberculosis disease is associated with genetic regulatory variation in Peruvians

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1. scibot 30 Jun 2024
  
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  plasmid_104991
  
  DOI: 10.1371/journal.pgen.1011313
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11208071/
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The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma

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1. scibot 03 Jun 2024
  
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  RRID:Addgene_104991
  
  DOI: 10.1126/sciadv.adm9449
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11141635/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation

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1. scibot 04 Feb 2024
  
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  104991
  
  DOI: 10.1186/s13045-024-01526-9
  
  Resource: RRID:Addgene_104991
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10835888/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

1
1. scibot 28 Jun 2023
  
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  RRID: Addgene_104991
  
  DOI: 10.1016/j.cell.2023.05.047
  
  Resource: RRID:Addgene_104991
  
  Curator: @sofiakhan13
  
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sciencedirect.com/science/article/pii/S0092867423005986
Jan 2023
www.sciencedirect.com www.sciencedirect.com

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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1. scibot 06 Jan 2023
  
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  RRID:Addgene_104991
  
  DOI: 10.1016/j.stem.2022.12.006
  
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sciencedirect.com/science/article/pii/S1934590922004908